Buphthalmos

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Buphthalmos
File:Autosomal recessive - en.svg
Synonyms	Congenital glaucoma, infantile glaucoma
Pronounce	N/A
Specialty	N/A
Symptoms	Enlarged eye, corneal edema, photophobia, tearing, blepharospasm
Complications	Vision loss, optic nerve damage
Onset	Infancy or early childhood
Duration	Chronic
Types	N/A
Causes	Genetic mutations, developmental anomalies
Risks	Family history, genetic predisposition
Diagnosis	Ophthalmic examination, intraocular pressure measurement, gonioscopy
Differential diagnosis	Primary congenital glaucoma, megalocornea, sclerocornea
Prevention	N/A
Treatment	Surgical intervention, medications to lower intraocular pressure
Medication	Beta blockers, carbonic anhydrase inhibitors, prostaglandin analogs
Prognosis	Variable, depends on severity and treatment
Frequency	Rare
Deaths	Rarely directly causes death, but can lead to significant visual impairment

File:Autosomal recessive - en.svg

Buphthalmos (also known as buphthalmia) is a medical condition characterized by an abnormal enlargement of the eyeball. This condition is often associated with congenital glaucoma, a type of glaucoma that occurs in infants and young children. The term "buphthalmos" is derived from the Greek words "bous" meaning "ox" and "ophthalmos" meaning "eye," reflecting the enlarged appearance of the eye.

Causes

Buphthalmos is primarily caused by increased intraocular pressure (IOP) within the eye, which leads to the stretching and enlargement of the eyeball. This increased pressure is typically due to congenital glaucoma, which can result from developmental anomalies in the eye's drainage system. Other potential causes include:

• Sturge-Weber syndrome
• Neurofibromatosis type 1
• Axenfeld-Rieger syndrome

Symptoms

The symptoms of buphthalmos can vary depending on the severity of the condition and the underlying cause. Common symptoms include:

• Enlarged eyeball
• Corneal edema
• Photophobia (sensitivity to light)
• Epiphora (excessive tearing)
• Blepharospasm (involuntary tight closure of the eyelids)
• Myopia (nearsightedness)

Diagnosis

The diagnosis of buphthalmos typically involves a comprehensive eye examination by an ophthalmologist. Diagnostic procedures may include:

• Measurement of intraocular pressure (IOP)
• Gonioscopy to examine the drainage angle of the eye
• Ultrasound biomicroscopy to assess the structure of the eye
• Optical coherence tomography (OCT) to evaluate the retina and optic nerve

Treatment

The treatment of buphthalmos aims to reduce intraocular pressure and prevent further damage to the eye. Treatment options may include:

• Medications to lower intraocular pressure
• Surgical procedures such as trabeculotomy, goniotomy, or trabeculectomy
• Laser therapy to improve fluid drainage

Early diagnosis and treatment are crucial to prevent vision loss and other complications associated with buphthalmos.

Prognosis

The prognosis for individuals with buphthalmos depends on the severity of the condition and the effectiveness of the treatment. With early intervention, many patients can achieve good control of intraocular pressure and preserve their vision. However, untreated or poorly managed buphthalmos can lead to significant visual impairment or blindness.

See also

• Glaucoma
• Congenital glaucoma
• Ophthalmology
• Intraocular pressure

External links

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