Renal cell carcinoma
Renal cell carcinoma (RCC) is a type of kidney cancer that originates in the lining of the proximal convoluted tubule, a part of the very small tubes in the kidney that transport waste molecules from the blood to the urine.
Signs and Symptoms
The classic triad of hematuria, pain, and an abdominal mass is only present in 10% of cases, and is generally indicative of more advanced disease. Today, most cases of RCC are asymptomatic and are detected incidentally on imaging for other reasons.
Causes
RCC is associated with several hereditary conditions, including Von Hippel-Lindau disease, hereditary leiomyomatosis and RCC, Birt-Hogg-Dubé syndrome, and hereditary papillary renal carcinoma.
Diagnosis
Diagnosis of RCC involves a combination of medical imaging (such as CT scanning or ultrasound), blood and urine tests, and often, a biopsy.
Treatment
Treatment options for RCC include surgery, radiation therapy, immunotherapy, targeted therapy, and in some cases, chemotherapy.
Prognosis
The prognosis for RCC varies widely depending on the stage at which the cancer is diagnosed.
See Also
References
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Renal cell carcinoma
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Clear cell renal cell carcinoma high magnification
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Renal clear cell carcinoma nephrectomy
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Papillary renal cell carcinoma
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Histopathology of chromophobe renal cell carcinoma
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Renal cell carcinoma
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Renal tumors by relative incidence and prognosis
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Kidney cancer
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Embolization kidney
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Large left renal tumor with tumor thrombus all the way to the heart
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