1,3-Bisphosphoglyceric acid

1,3-Bisphosphoglyceric acid

Structural formula of 1,3-Bisphosphoglyceric acid

3D ball-and-stick model of 1,3-Bisphosphoglyceric acid

1,3-Bisphosphoglyceric acid (1,3-BPG) is a metabolite in the glycolysis pathway. It is an important intermediate in the conversion of glucose to pyruvate, and it plays a crucial role in the production of ATP.

Structure

1,3-Bisphosphoglyceric acid is a carboxylic acid with two phosphate groups attached to the first and third carbon atoms of the glyceric acid backbone. This structure allows it to participate in high-energy phosphate transfer reactions.

Role in Glycolysis

In the glycolysis pathway, 1,3-Bisphosphoglyceric acid is formed from glyceraldehyde 3-phosphate by the enzyme glyceraldehyde 3-phosphate dehydrogenase. This reaction involves the reduction of NAD+ to NADH and the addition of an inorganic phosphate group.

1,3-Bisphosphoglyceric acid is then converted to 3-phosphoglycerate by the enzyme phosphoglycerate kinase. This step is coupled with the production of ATP from ADP, making it a key step in the energy yield of glycolysis.

Role in the Calvin Cycle

In photosynthesis, 1,3-Bisphosphoglyceric acid is also an intermediate in the Calvin cycle. It is formed from 3-phosphoglycerate and is subsequently reduced to glyceraldehyde 3-phosphate using NADPH and ATP.

Related Compounds

1,3-Bisphosphoglyceric acid is closely related to other phosphorylated intermediates in glycolysis, such as 3-phosphoglycerate and 2,3-bisphosphoglycerate, the latter of which is important in hemoglobin function and oxygen release.

Related pages

• Glycolysis
• Calvin cycle
• Adenosine triphosphate
• Nicotinamide adenine dinucleotide

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  1,3-Bisphosphoglyceric acid structural formula
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  1,3-Bisphosphoglyceric acid 3D ball model