Oxprenoic acid
A synthetic steroid with antiandrogen properties
| Oxprenoic acid | |
|---|---|
| |
| INN | |
| Drug class | |
| Routes of administration | |
| Pregnancy category | |
| Bioavailability | |
| Metabolism | |
| Elimination half-life | |
| Excretion | |
| Legal status | |
| CAS Number | |
| PubChem | |
| DrugBank | |
| ChemSpider | |
| KEGG | |
Oxprenoic acid is a synthetic steroid with antiandrogen properties. It is primarily used in the treatment of conditions related to androgen excess.
Chemical structure[edit]
Oxprenoic acid is a derivative of progesterone, featuring a cyclopentanone ring attached to a butanoic acid moiety. This structure is responsible for its biological activity as an antiandrogen.
Mechanism of action[edit]
Oxprenoic acid functions by inhibiting the action of androgens, which are male sex hormones such as testosterone. It competes with androgens for binding to the androgen receptor, thereby reducing the effects of these hormones in the body.
Clinical uses[edit]
Oxprenoic acid is used in the management of conditions such as hirsutism, acne, and androgenic alopecia, which are often caused by excessive androgen activity. It may also be used in the treatment of polycystic ovary syndrome (PCOS), where androgen excess is a common feature.
Pharmacokinetics[edit]
The pharmacokinetic profile of oxprenoic acid includes its absorption, distribution, metabolism, and excretion. It is typically administered orally and undergoes hepatic metabolism. The metabolites are excreted primarily via the kidneys.
Side effects[edit]
Common side effects of oxprenoic acid include nausea, headache, and dizziness. As with other antiandrogens, it may also cause gynecomastia in males due to its effects on hormone balance.
Related compounds[edit]
Oxprenoic acid is related to other antiandrogens such as spironolactone and cyproterone acetate. These compounds share similar mechanisms of action and are used in the treatment of similar conditions.
Related pages[edit]
Ad. Transform your life with W8MD's
GLP-1 weight loss injections special from $29.99 with insurance
|
WikiMD Medical Encyclopedia |
Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
