5F-PCN

Synthetic cannabinoid

5F-PCN
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5F-PCN is a synthetic cannabinoid that has been used in scientific research and is a potent agonist of the cannabinoid receptors. It is structurally related to other synthetic cannabinoids such as 5F-PB-22 and 5F-ADB.

Chemical structure

5F-PCN belongs to the class of indole-based synthetic cannabinoids. Its chemical structure is characterized by a 5-fluoropentyl chain attached to the nitrogen atom of the indole core, and a nitrile group at the 3-position of the indole ring. This structure is similar to other synthetic cannabinoids, which often feature a core indole or indazole structure with various substituents.

Pharmacology

5F-PCN acts as a potent agonist at the CB₁ and CB₂ cannabinoid receptors. These receptors are part of the endocannabinoid system, which plays a role in regulating various physiological processes including mood, memory, and appetite. The activation of these receptors by synthetic cannabinoids can lead to psychoactive effects similar to those of tetrahydrocannabinol (THC), the active component of cannabis.

Legal status

The legal status of 5F-PCN varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of medical use. It is often included in legislation targeting synthetic cannabinoids as a class.

Health effects

The use of synthetic cannabinoids like 5F-PCN can lead to a range of adverse health effects. These may include tachycardia, hypertension, nausea, vomiting, anxiety, and hallucinations. In severe cases, use can result in seizures, psychosis, and renal failure.

Related pages

• Synthetic cannabinoids
• Cannabinoid receptor
• 5F-PB-22
• 5F-ADB

Gallery

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  Chemical structure of 5F-PCN