EC-hippocampus system

General Information
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TA98
TA2
FMA
Details
System	Nervous system
Artery
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Nerve
Lymphatic drainage
Precursor
Function
Identifiers
Clinical significance
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The EC-hippocampus system is a critical component of the brain involved in memory and navigation. It primarily consists of the entorhinal cortex (EC) and the hippocampus.

Structure

The EC-hippocampus system is part of the limbic system, which is involved in emotion and memory. The entorhinal cortex serves as a major input and output structure for the hippocampus, facilitating the flow of information between the neocortex and the hippocampus.

Entorhinal Cortex

The entorhinal cortex is located in the medial temporal lobe and is a crucial hub in the brain's memory network. It is involved in the processing of spatial memory and navigation.

Hippocampus

The hippocampus is a small, curved formation in the brain that plays an essential role in the formation of new memories and is also associated with learning and emotions.

Function

The EC-hippocampus system is primarily responsible for the consolidation of information from short-term memory to long-term memory, and in spatial memory that enables navigation.

Memory

The hippocampus is involved in the formation of new memories and is essential for declarative memory, which includes facts and events. The entorhinal cortex provides the hippocampus with sensory information and is involved in the initial processing of memory traces.

Navigation

The entorhinal cortex contains specialized neurons known as grid cells, which are involved in spatial navigation. These cells help the brain to create a cognitive map of the environment.

Clinical Significance

Damage to the EC-hippocampus system can result in memory disorders such as Alzheimer's disease and amnesia. The hippocampus is one of the first regions of the brain to suffer damage in Alzheimer's disease, leading to the characteristic memory loss and disorientation.

Research

Ongoing research is focused on understanding the precise mechanisms of memory encoding and retrieval in the EC-hippocampus system. Studies using neuroimaging and electrophysiology are providing insights into how neurons in this system interact during memory tasks.

See also

• Limbic system
• Memory
• Neuroscience
• Alzheimer's disease

External links

• EC-hippocampus system on WikiMD