Chloroxylenol

Overview of the antiseptic agent Chloroxylenol

Chloroxylenol
File:Chloroxylenol.svg
INN
Drug class	Antiseptic
Routes of administration	Topical
Pregnancy category
Bioavailability
Metabolism
Elimination half-life
Excretion
Legal status	OTC
CAS Number	88-04-0
PubChem
DrugBank
ChemSpider
KEGG

Chloroxylenol is a broad-spectrum antimicrobial agent commonly used as an antiseptic and disinfectant. It is effective against a wide range of bacteria, fungi, and viruses, making it a popular choice in healthcare settings and household products.

Chemical Properties

Chloroxylenol, also known as para-chloro-meta-xylenol (PCMX), is a chlorinated phenolic compound. Its chemical formula is C₈H₉ClO, and it has a molecular weight of 156.61 g/mol. The compound appears as a white to off-white crystalline solid with a mild phenolic odor.

Mechanism of Action

Chloroxylenol works by disrupting the cell wall and membrane of microorganisms, leading to cell lysis and death. It is particularly effective against Gram-positive bacteria, although it also has activity against Gram-negative bacteria, fungi, and some viruses.

Uses

Chloroxylenol is widely used in various applications, including:

• Antiseptic Soaps and Handwashes: It is a key ingredient in many antiseptic soaps and handwashes, such as Dettol, where it helps reduce the spread of infections.
• Surface Disinfectants: Used in hospitals and clinics to disinfect surfaces and equipment.
• Wound Cleansers: Applied to minor cuts, abrasions, and burns to prevent infection.
• Household Cleaners: Incorporated into household cleaning products to sanitize surfaces.

Safety and Precautions

Chloroxylenol is generally safe for use in the concentrations found in consumer products. However, it can cause skin irritation in some individuals, particularly with prolonged exposure. It should not be ingested, and care should be taken to avoid contact with the eyes.

Regulation and Availability

Chloroxylenol is available over-the-counter in many countries. It is regulated by health authorities to ensure safety and efficacy in consumer products.

Also see

• Antiseptic
• Disinfectant
• Phenolic compounds
• Infection control

References

• "Chloroxylenol." PubChem, National Center for Biotechnology Information.
• "Antiseptics and Disinfectants: Activity, Action, and Resistance." Clinical Microbiology Reviews.