Pilsicainide

Pilsicainide is a class 1c antiarrhythmic agent that is often used in the treatment of cardiac arrhythmias. It is a sodium channel blocker that is primarily used in the treatment of atrial fibrillation and atrial flutter.

Mechanism of Action

Pilsicainide works by blocking the fast sodium channels in the heart, which in turn slows down the heart rate. This helps to restore a normal rhythm in patients with atrial fibrillation or atrial flutter.

Uses

Pilsicainide is primarily used to treat atrial fibrillation and atrial flutter. It may also be used in the treatment of other types of cardiac arrhythmias, depending on the patient's specific condition and the discretion of the treating physician.

Side Effects

Like all medications, pilsicainide can cause side effects. These may include dizziness, nausea, vomiting, and shortness of breath. In rare cases, pilsicainide may cause more serious side effects such as heart failure or ventricular fibrillation.

Contraindications

Pilsicainide is contraindicated in patients with certain conditions, including heart block, sick sinus syndrome, and cardiogenic shock. It should also not be used in patients with a history of hypersensitivity to pilsicainide or any of its components.

Interactions

Pilsicainide may interact with other medications, including other antiarrhythmic agents, beta blockers, and certain antidepressants. Patients should always inform their healthcare provider of all medications they are currently taking to avoid potential interactions.

See Also

• Antiarrhythmic agent
• Atrial fibrillation
• Atrial flutter

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