Latamoxef

Latamoxef (or moxalactam) is an antibiotic in the cephalosporin class. It is an oxacephem, a subclass of beta-lactam antibiotics that includes flomoxef and cefoperazone. Latamoxef was discovered by scientists at Shionogi.

Medical uses

Latamoxef is used to treat severe infections caused by susceptible strains of microorganisms. It is particularly effective against gram-negative bacteria, including Pseudomonas aeruginosa, Escherichia coli, and Klebsiella pneumoniae. It is also used in the treatment of septicemia, meningitis, and infections of the urinary tract, respiratory tract, skin and skin structure, and intra-abdominal region.

Pharmacology

Latamoxef is a broad-spectrum antibiotic that inhibits the synthesis of bacterial cell walls, leading to cell death. It is resistant to most beta-lactamases and is active against a wide range of gram-negative and gram-positive bacteria.

Side effects

Common side effects of latamoxef include diarrhea, nausea, vomiting, and rash. Less common side effects include anemia, thrombocytopenia, and leukopenia. In rare cases, latamoxef can cause serious allergic reactions.

History

Latamoxef was discovered in the 1970s by scientists at Shionogi. It was approved for medical use in the United States in 1981.

See also

• List of antibiotics
• Oxacephem
• Cephalosporin

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