Fabomotizole

Fabomotizole (also known as Afobazole) is an anxiolytic medication developed in Russia in the late 20th century. It is used primarily in the treatment of anxiety disorders, including generalized anxiety disorder and panic disorder.

Pharmacology

Fabomotizole is a sigma receptor agonist, specifically at the σ1 subtype. It also has some affinity for the σ2 subtype. The sigma receptor is a type of protein found in the brain and other tissues, which is thought to play a role in the regulation of neurotransmitter release.

Clinical Use

Fabomotizole is used in the treatment of various types of anxiety disorders. It has been shown to be effective in reducing the symptoms of generalized anxiety disorder and panic disorder. It is also used in the treatment of insomnia related to anxiety, and in the management of withdrawal syndromes from alcohol and other sedative drugs.

Side Effects

The most common side effects of Fabomotizole include drowsiness, dizziness, and nausea. In rare cases, it can cause allergic reactions, including rash, itching, and swelling.

See Also

• Anxiolytic
• Sigma receptor
• Generalized anxiety disorder
• Panic disorder

References

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