Prurigo gestationis

Prurigo gestationis
Synonyms	Pruritic folliculitis of pregnancy, Pruritic urticarial papules and plaques of pregnancy (PUPPP)
Pronounce	N/A
Specialty	N/A
Symptoms	Itchy papules and plaques on the skin, primarily on the abdomen and extremities
Complications	N/A
Onset	During pregnancy, typically in the second or third trimester
Duration	Until delivery, with resolution postpartum
Types	N/A
Causes	Unknown, possibly related to hormonal changes or immune system alterations during pregnancy
Risks	Pregnancy, especially first pregnancies
Diagnosis	Clinical evaluation, exclusion of other dermatoses of pregnancy
Differential diagnosis	Intrahepatic cholestasis of pregnancy, Pemphigoid gestationis, Atopic eruption of pregnancy
Prevention	N/A
Treatment	Topical corticosteroids, antihistamines, emollients
Medication	N/A
Prognosis	N/A
Frequency	Rare, estimated to affect 1 in 300 to 1 in 450 pregnancies
Deaths	N/A

A skin condition occurring during pregnancy

Prurigo gestationis is a dermatological condition that occurs during pregnancy. It is characterized by the development of itchy papules and nodules on the skin, typically appearing in the second or third trimester. This condition is considered a type of pruritic eruption of pregnancy, which encompasses several skin disorders that can occur during pregnancy.

Presentation

Prurigo gestationis usually presents with small, itchy bumps on the skin. These lesions are often found on the extremities, such as the arms and legs, but can also appear on the abdomen and other parts of the body. The papules are typically erythematous and can become excoriated due to scratching.

Pathophysiology

The exact cause of prurigo gestationis is not well understood. It is believed to be related to the immune system changes that occur during pregnancy. Hormonal fluctuations and increased levels of certain cytokines may also play a role in the development of this condition.

Diagnosis

Diagnosis of prurigo gestationis is primarily clinical, based on the appearance of the skin lesions and the timing of their onset during pregnancy. A thorough medical history and physical examination are essential. In some cases, a skin biopsy may be performed to rule out other conditions with similar presentations, such as atopic dermatitis or polymorphic eruption of pregnancy.

Management

The management of prurigo gestationis focuses on relieving the symptoms, particularly the intense itching. Treatment options may include:

• Topical corticosteroids to reduce inflammation and itching.
• Antihistamines to help control itching and improve sleep.
• Emollients and moisturizers to soothe the skin and prevent dryness.

In severe cases, systemic treatments may be considered, but these are typically avoided during pregnancy unless absolutely necessary due to potential risks to the fetus.

Prognosis

Prurigo gestationis is a benign condition that does not pose a risk to the mother or the fetus. The symptoms usually resolve after delivery, although they may persist for a short period postpartum. Recurrence in subsequent pregnancies is possible but not guaranteed.

Related pages

• Pruritic urticarial papules and plaques of pregnancy
• Intrahepatic cholestasis of pregnancy
• Pemphigoid gestationis
• Atopic eruption of pregnancy