Myxedema: Difference between revisions
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{{Infobox medical condition | |||
| name = Myxedema | |||
| image = [[File:Hyaluronan.svg|left|thumb|Structure of hyaluronan, a component involved in myxedema]] | |||
| caption = Structure of hyaluronan, a component involved in myxedema | |||
| field = [[Endocrinology]] | |||
| symptoms = [[Fatigue]], [[weight gain]], [[cold intolerance]], [[swelling]] of the skin | |||
| complications = [[Heart failure]], [[coma]], [[infection]] | |||
| onset = Gradual | |||
| duration = Long-term | |||
| causes = [[Hypothyroidism]], [[Hashimoto's thyroiditis]], [[thyroid surgery]] | |||
| risks = [[Autoimmune disease]], [[iodine deficiency]], [[radiation therapy]] | |||
| diagnosis = [[Thyroid function tests]], [[clinical examination]] | |||
| differential = [[Cushing's syndrome]], [[nephrotic syndrome]], [[congestive heart failure]] | |||
| treatment = [[Levothyroxine]], [[thyroid hormone replacement therapy]] | |||
| medication = [[Levothyroxine]] | |||
| prognosis = Generally good with treatment | |||
| frequency = More common in [[women]] and [[elderly]] | |||
}} | |||
[[File:Myxedema face.png|Myxedema face|thumb|left]] | |||
[[File:Myxedema standing.png|Myxedema standing|thumb]] | |||
[[File:BASA-3K-7-529-35(7)-Myxedema.jpg|Myxedema|thumb|left]] | |||
'''Myxedema''' is a term used in medicine to describe a severe form of [[hypothyroidism]], a condition characterized by an underactive [[thyroid gland]]. The term is often used interchangeably with hypothyroidism, but myxedema specifically refers to a severe and life-threatening form of the condition. | '''Myxedema''' is a term used in medicine to describe a severe form of [[hypothyroidism]], a condition characterized by an underactive [[thyroid gland]]. The term is often used interchangeably with hypothyroidism, but myxedema specifically refers to a severe and life-threatening form of the condition. | ||
== Symptoms == | == Symptoms == | ||
The symptoms of myxedema can vary widely and may include fatigue, weight gain, cold intolerance, constipation, and depression. In severe cases, myxedema can lead to a life-threatening condition known as myxedema coma, which is characterized by decreased breathing, low blood pressure, low body temperature, and unresponsiveness. | The symptoms of myxedema can vary widely and may include fatigue, weight gain, cold intolerance, constipation, and depression. In severe cases, myxedema can lead to a life-threatening condition known as myxedema coma, which is characterized by decreased breathing, low blood pressure, low body temperature, and unresponsiveness. | ||
== Causes == | == Causes == | ||
Myxedema is most commonly caused by an underactive thyroid gland, which can be due to a variety of factors including autoimmune disease, certain medications, and surgical removal of the thyroid gland. Other causes can include pituitary or hypothalamic disease, severe illness, or certain medications. | Myxedema is most commonly caused by an underactive thyroid gland, which can be due to a variety of factors including autoimmune disease, certain medications, and surgical removal of the thyroid gland. Other causes can include pituitary or hypothalamic disease, severe illness, or certain medications. | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of myxedema is typically based on a combination of physical examination findings and laboratory tests. These tests may include measurements of thyroid hormone levels in the blood, as well as imaging studies of the thyroid gland. | Diagnosis of myxedema is typically based on a combination of physical examination findings and laboratory tests. These tests may include measurements of thyroid hormone levels in the blood, as well as imaging studies of the thyroid gland. | ||
== Treatment == | == Treatment == | ||
Treatment for myxedema typically involves replacement of the missing thyroid hormone, usually with a medication called levothyroxine. In severe cases, hospitalization may be required for intensive care and treatment. | Treatment for myxedema typically involves replacement of the missing thyroid hormone, usually with a medication called levothyroxine. In severe cases, hospitalization may be required for intensive care and treatment. | ||
== See also == | == See also == | ||
* [[Hypothyroidism]] | * [[Hypothyroidism]] | ||
* [[Thyroid gland]] | * [[Thyroid gland]] | ||
* [[Levothyroxine]] | * [[Levothyroxine]] | ||
[[Category:Endocrine diseases]] | [[Category:Endocrine diseases]] | ||
[[Category:Thyroid disease]] | [[Category:Thyroid disease]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 04:43, 13 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's weight loss doctor NYC
Philadelphia GLP-1 weight loss and GLP-1 clinic NYC
| Myxedema | |
|---|---|
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Fatigue, weight gain, cold intolerance, swelling of the skin |
| Complications | Heart failure, coma, infection |
| Onset | Gradual |
| Duration | Long-term |
| Types | N/A |
| Causes | Hypothyroidism, Hashimoto's thyroiditis, thyroid surgery |
| Risks | Autoimmune disease, iodine deficiency, radiation therapy |
| Diagnosis | Thyroid function tests, clinical examination |
| Differential diagnosis | Cushing's syndrome, nephrotic syndrome, congestive heart failure |
| Prevention | N/A |
| Treatment | Levothyroxine, thyroid hormone replacement therapy |
| Medication | Levothyroxine |
| Prognosis | Generally good with treatment |
| Frequency | More common in women and elderly |
| Deaths | N/A |



Myxedema is a term used in medicine to describe a severe form of hypothyroidism, a condition characterized by an underactive thyroid gland. The term is often used interchangeably with hypothyroidism, but myxedema specifically refers to a severe and life-threatening form of the condition.
Symptoms[edit]
The symptoms of myxedema can vary widely and may include fatigue, weight gain, cold intolerance, constipation, and depression. In severe cases, myxedema can lead to a life-threatening condition known as myxedema coma, which is characterized by decreased breathing, low blood pressure, low body temperature, and unresponsiveness.
Causes[edit]
Myxedema is most commonly caused by an underactive thyroid gland, which can be due to a variety of factors including autoimmune disease, certain medications, and surgical removal of the thyroid gland. Other causes can include pituitary or hypothalamic disease, severe illness, or certain medications.
Diagnosis[edit]
Diagnosis of myxedema is typically based on a combination of physical examination findings and laboratory tests. These tests may include measurements of thyroid hormone levels in the blood, as well as imaging studies of the thyroid gland.
Treatment[edit]
Treatment for myxedema typically involves replacement of the missing thyroid hormone, usually with a medication called levothyroxine. In severe cases, hospitalization may be required for intensive care and treatment.
