Myeloid sarcoma: Difference between revisions
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{{Infobox medical condition | |||
| name = Myeloid sarcoma | |||
| image = [[File:Chloroma_-_very_high_mag.jpg|left|thumb|Myeloid sarcoma under microscope]] | |||
| caption = Myeloid sarcoma under microscope | |||
| field = [[Hematology]] | |||
| synonyms = [[Granulocytic sarcoma]], [[chloroma]] | |||
| symptoms = [[Lump]] or [[mass]] in [[skin]], [[bone]], or other tissues | |||
| complications = May progress to [[acute myeloid leukemia]] | |||
| onset = Can occur at any age | |||
| duration = Variable | |||
| causes = [[Myeloid cell]] proliferation | |||
| risks = [[Acute myeloid leukemia]], [[myelodysplastic syndrome]] | |||
| diagnosis = [[Biopsy]], [[immunohistochemistry]] | |||
| differential = [[Lymphoma]], [[extramedullary hematopoiesis]] | |||
| treatment = [[Chemotherapy]], [[radiation therapy]], [[surgery]] | |||
| prognosis = Depends on underlying condition | |||
| frequency = Rare | |||
}} | |||
[[File:Chloroma CMUJ.jpg|Myeloid sarcoma|thumb|left]] | |||
'''Myeloid sarcoma''' (also known as '''granulocytic sarcoma''', '''chloroma''', '''myeloblastoma''', or '''extramedullary myeloid tumor''') is a rare type of cancer associated with [[hematological malignancies]] and characterized by the presence of immature [[white blood cells]] (myeloid cells) forming a mass outside the [[bone marrow]]. | '''Myeloid sarcoma''' (also known as '''granulocytic sarcoma''', '''chloroma''', '''myeloblastoma''', or '''extramedullary myeloid tumor''') is a rare type of cancer associated with [[hematological malignancies]] and characterized by the presence of immature [[white blood cells]] (myeloid cells) forming a mass outside the [[bone marrow]]. | ||
== Signs and Symptoms == | == Signs and Symptoms == | ||
The symptoms of myeloid sarcoma can vary greatly depending on the location of the tumor. Common symptoms may include pain, swelling, or discomfort in the affected area. If the tumor is located in the [[central nervous system]], symptoms may include headaches, seizures, or changes in vision. | The symptoms of myeloid sarcoma can vary greatly depending on the location of the tumor. Common symptoms may include pain, swelling, or discomfort in the affected area. If the tumor is located in the [[central nervous system]], symptoms may include headaches, seizures, or changes in vision. | ||
== Causes == | == Causes == | ||
Myeloid sarcoma is often associated with other hematological disorders, such as [[acute myeloid leukemia]] (AML), [[chronic myeloid leukemia]] (CML), or [[myelodysplastic syndrome]] (MDS). It can occur at any age, but is more common in adults than in children. | Myeloid sarcoma is often associated with other hematological disorders, such as [[acute myeloid leukemia]] (AML), [[chronic myeloid leukemia]] (CML), or [[myelodysplastic syndrome]] (MDS). It can occur at any age, but is more common in adults than in children. | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of myeloid sarcoma can be challenging due to its rarity and the wide range of possible symptoms. It is typically diagnosed through a combination of [[medical imaging]], [[biopsy]], and [[cytogenetic]] analysis. | Diagnosis of myeloid sarcoma can be challenging due to its rarity and the wide range of possible symptoms. It is typically diagnosed through a combination of [[medical imaging]], [[biopsy]], and [[cytogenetic]] analysis. | ||
== Treatment == | == Treatment == | ||
Treatment for myeloid sarcoma typically involves [[chemotherapy]], and may also include [[radiation therapy]] or [[stem cell transplantation]]. The choice of treatment depends on the patient's overall health, the location and size of the tumor, and the presence of any associated hematological disorders. | Treatment for myeloid sarcoma typically involves [[chemotherapy]], and may also include [[radiation therapy]] or [[stem cell transplantation]]. The choice of treatment depends on the patient's overall health, the location and size of the tumor, and the presence of any associated hematological disorders. | ||
== Prognosis == | == Prognosis == | ||
The prognosis for myeloid sarcoma varies depending on a number of factors, including the patient's age, overall health, and the presence of any associated hematological disorders. In general, the prognosis is poor, with a median survival time of less than a year. | The prognosis for myeloid sarcoma varies depending on a number of factors, including the patient's age, overall health, and the presence of any associated hematological disorders. In general, the prognosis is poor, with a median survival time of less than a year. | ||
== See Also == | == See Also == | ||
* [[Acute myeloid leukemia]] | * [[Acute myeloid leukemia]] | ||
* [[Chronic myeloid leukemia]] | * [[Chronic myeloid leukemia]] | ||
* [[Myelodysplastic syndrome]] | * [[Myelodysplastic syndrome]] | ||
== References == | == References == | ||
<references /> | <references /> | ||
[[Category:Rare cancers]] | [[Category:Rare cancers]] | ||
[[Category:Hematological malignancies]] | [[Category:Hematological malignancies]] | ||
[[Category:Leukemia]] | [[Category:Leukemia]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 05:53, 9 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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| Myeloid sarcoma | |
|---|---|
 | |
| Synonyms | Granulocytic sarcoma, chloroma |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Lump or mass in skin, bone, or other tissues |
| Complications | May progress to acute myeloid leukemia |
| Onset | Can occur at any age |
| Duration | Variable |
| Types | N/A |
| Causes | Myeloid cell proliferation |
| Risks | Acute myeloid leukemia, myelodysplastic syndrome |
| Diagnosis | Biopsy, immunohistochemistry |
| Differential diagnosis | Lymphoma, extramedullary hematopoiesis |
| Prevention | N/A |
| Treatment | Chemotherapy, radiation therapy, surgery |
| Medication | N/A |
| Prognosis | Depends on underlying condition |
| Frequency | Rare |
| Deaths | N/A |
Myeloid sarcoma (also known as granulocytic sarcoma, chloroma, myeloblastoma, or extramedullary myeloid tumor) is a rare type of cancer associated with hematological malignancies and characterized by the presence of immature white blood cells (myeloid cells) forming a mass outside the bone marrow.
Signs and Symptoms[edit]
The symptoms of myeloid sarcoma can vary greatly depending on the location of the tumor. Common symptoms may include pain, swelling, or discomfort in the affected area. If the tumor is located in the central nervous system, symptoms may include headaches, seizures, or changes in vision.
Causes[edit]
Myeloid sarcoma is often associated with other hematological disorders, such as acute myeloid leukemia (AML), chronic myeloid leukemia (CML), or myelodysplastic syndrome (MDS). It can occur at any age, but is more common in adults than in children.
Diagnosis[edit]
Diagnosis of myeloid sarcoma can be challenging due to its rarity and the wide range of possible symptoms. It is typically diagnosed through a combination of medical imaging, biopsy, and cytogenetic analysis.
Treatment[edit]
Treatment for myeloid sarcoma typically involves chemotherapy, and may also include radiation therapy or stem cell transplantation. The choice of treatment depends on the patient's overall health, the location and size of the tumor, and the presence of any associated hematological disorders.
Prognosis[edit]
The prognosis for myeloid sarcoma varies depending on a number of factors, including the patient's age, overall health, and the presence of any associated hematological disorders. In general, the prognosis is poor, with a median survival time of less than a year.
See Also[edit]
References[edit]
<references />
