Loin pain hematuria syndrome: Difference between revisions
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[[File:Gray1125.png| | {{SI}} | ||
{{Infobox medical condition | |||
| name = Loin pain hematuria syndrome | |||
| image = [[File:Gray1125.png|250px]] | |||
| caption = Diagram of the [[kidney]] and surrounding structures | |||
| synonyms = LPHS | |||
| pronounce = | |||
| specialty = [[Nephrology]] | |||
| symptoms = [[Loin pain]], [[hematuria]] | |||
| onset = | |||
| duration = | |||
| types = | |||
| causes = Unknown | |||
| risks = | |||
| diagnosis = [[Clinical diagnosis]], [[urinalysis]], [[imaging studies]] | |||
| differential = [[Kidney stones]], [[urinary tract infection]], [[glomerulonephritis]] | |||
| prevention = | |||
| treatment = [[Pain management]], [[surgical intervention]] | |||
| medication = [[Analgesics]], [[antidepressants]] | |||
| prognosis = Variable | |||
| frequency = Rare | |||
| deaths = | |||
}} | |||
'''Loin pain hematuria syndrome''' ('''LPHS''') is a rare medical condition characterized by severe, unexplained [[flank pain]] (loin pain) and [[hematuria]] (blood in the urine). The syndrome primarily affects young adults and can lead to significant morbidity due to chronic pain and recurrent episodes of hematuria. | |||
==Presentation== | ==Presentation== | ||
Patients with LPHS typically present with severe, unilateral or bilateral flank pain that can be constant or intermittent. The pain is often described as sharp, stabbing, or throbbing and can be debilitating. Hematuria, which may be visible (gross hematuria) or detectable only under a microscope (microscopic hematuria), is a hallmark of the condition. Other symptoms may include [[nausea]], [[vomiting]], and [[fatigue]]. | Patients with LPHS typically present with severe, unilateral or bilateral flank pain that can be constant or intermittent. The pain is often described as sharp, stabbing, or throbbing and can be debilitating. Hematuria, which may be visible (gross hematuria) or detectable only under a microscope (microscopic hematuria), is a hallmark of the condition. Other symptoms may include [[nausea]], [[vomiting]], and [[fatigue]]. | ||
==Etiology== | ==Etiology== | ||
The exact cause of LPHS is unknown. Several theories have been proposed, including: | The exact cause of LPHS is unknown. Several theories have been proposed, including: | ||
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* [[Urological disorders]] | * [[Urological disorders]] | ||
* [[Autoimmune disorders]] | * [[Autoimmune disorders]] | ||
==Diagnosis== | ==Diagnosis== | ||
The diagnosis of LPHS is primarily clinical, based on the characteristic symptoms of loin pain and hematuria. Diagnostic tests may include: | The diagnosis of LPHS is primarily clinical, based on the characteristic symptoms of loin pain and hematuria. Diagnostic tests may include: | ||
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* [[Imaging studies]] such as [[ultrasound]], [[CT scan]], or [[MRI]] to rule out other causes of flank pain and hematuria | * [[Imaging studies]] such as [[ultrasound]], [[CT scan]], or [[MRI]] to rule out other causes of flank pain and hematuria | ||
* [[Renal biopsy]] in some cases to exclude other renal pathologies | * [[Renal biopsy]] in some cases to exclude other renal pathologies | ||
==Management== | ==Management== | ||
Management of LPHS is challenging and often requires a multidisciplinary approach. Treatment options may include: | Management of LPHS is challenging and often requires a multidisciplinary approach. Treatment options may include: | ||
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* [[Surgical interventions]] such as [[renal denervation]] or [[nephrectomy]] in severe cases | * [[Surgical interventions]] such as [[renal denervation]] or [[nephrectomy]] in severe cases | ||
* [[Supportive care]] and [[psychological support]] | * [[Supportive care]] and [[psychological support]] | ||
==Prognosis== | ==Prognosis== | ||
The prognosis of LPHS varies. Some patients may experience spontaneous resolution of symptoms, while others may have chronic, persistent pain and recurrent hematuria. The condition can significantly impact the quality of life and may lead to [[depression]] and [[anxiety]]. | The prognosis of LPHS varies. Some patients may experience spontaneous resolution of symptoms, while others may have chronic, persistent pain and recurrent hematuria. The condition can significantly impact the quality of life and may lead to [[depression]] and [[anxiety]]. | ||
==See also== | |||
== | |||
* [[Flank pain]] | * [[Flank pain]] | ||
* [[Hematuria]] | * [[Hematuria]] | ||
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* [[Nephrectomy]] | * [[Nephrectomy]] | ||
[[Category:Kidney diseases]] | [[Category:Kidney diseases]] | ||
[[Category:Rare diseases]] | [[Category:Rare diseases]] | ||
[[Category:Medical conditions]] | [[Category:Medical conditions]] | ||
{{medicine-stub}} | {{medicine-stub}} | ||
Latest revision as of 04:01, 8 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Loin pain hematuria syndrome | |
|---|---|
| |
| Synonyms | LPHS |
| Pronounce | |
| Specialty | Nephrology |
| Symptoms | Loin pain, hematuria |
| Complications | N/A |
| Onset | |
| Duration | |
| Types | |
| Causes | Unknown |
| Risks | |
| Diagnosis | Clinical diagnosis, urinalysis, imaging studies |
| Differential diagnosis | Kidney stones, urinary tract infection, glomerulonephritis |
| Prevention | |
| Treatment | Pain management, surgical intervention |
| Medication | Analgesics, antidepressants |
| Prognosis | Variable |
| Frequency | Rare |
| Deaths | |
Loin pain hematuria syndrome (LPHS) is a rare medical condition characterized by severe, unexplained flank pain (loin pain) and hematuria (blood in the urine). The syndrome primarily affects young adults and can lead to significant morbidity due to chronic pain and recurrent episodes of hematuria.
Presentation[edit]
Patients with LPHS typically present with severe, unilateral or bilateral flank pain that can be constant or intermittent. The pain is often described as sharp, stabbing, or throbbing and can be debilitating. Hematuria, which may be visible (gross hematuria) or detectable only under a microscope (microscopic hematuria), is a hallmark of the condition. Other symptoms may include nausea, vomiting, and fatigue.
Etiology[edit]
The exact cause of LPHS is unknown. Several theories have been proposed, including:
Diagnosis[edit]
The diagnosis of LPHS is primarily clinical, based on the characteristic symptoms of loin pain and hematuria. Diagnostic tests may include:
- Urinalysis to detect hematuria
- Imaging studies such as ultrasound, CT scan, or MRI to rule out other causes of flank pain and hematuria
- Renal biopsy in some cases to exclude other renal pathologies
Management[edit]
Management of LPHS is challenging and often requires a multidisciplinary approach. Treatment options may include:
- Pain management with analgesics, including nonsteroidal anti-inflammatory drugs (NSAIDs) and opioids
- Nerve blocks or neurostimulation techniques
- Surgical interventions such as renal denervation or nephrectomy in severe cases
- Supportive care and psychological support
Prognosis[edit]
The prognosis of LPHS varies. Some patients may experience spontaneous resolution of symptoms, while others may have chronic, persistent pain and recurrent hematuria. The condition can significantly impact the quality of life and may lead to depression and anxiety.
See also[edit]
