Shoulder pad sign: Difference between revisions
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{{Infobox medical condition | |||
| name = Shoulder pad sign | |||
| image = [[File:Shoulder_Pad_Sign_2.jpg|250px]] | |||
| caption = Clinical presentation of the shoulder pad sign | |||
| specialty = [[Rheumatology]], [[Oncology]] | |||
| symptoms = Swelling over the [[shoulder]] area | |||
| causes = [[Primary amyloidosis]], [[Multiple myeloma]] | |||
| diagnosis = [[Physical examination]], [[Imaging studies]], [[Biopsy]] | |||
| differential = [[Lipoma]], [[Lymphoma]], [[Soft tissue sarcoma]] | |||
| treatment = Depends on underlying cause; may include [[chemotherapy]], [[radiation therapy]], or [[surgical intervention]] | |||
| prognosis = Varies based on underlying condition | |||
| frequency = Rare | |||
}} | |||
{{Short description|Clinical sign in medicine}} | {{Short description|Clinical sign in medicine}} | ||
The '''shoulder pad sign''' is a clinical manifestation characterized by the presence of soft tissue swelling over the shoulders, giving the appearance of shoulder pads. This sign is most commonly associated with [[amyloidosis]], particularly [[primary amyloidosis]] (AL amyloidosis), where there is deposition of amyloid protein in the soft tissues. | The '''shoulder pad sign''' is a clinical manifestation characterized by the presence of soft tissue swelling over the shoulders, giving the appearance of shoulder pads. This sign is most commonly associated with [[amyloidosis]], particularly [[primary amyloidosis]] (AL amyloidosis), where there is deposition of amyloid protein in the soft tissues. | ||
== Pathophysiology == | == Pathophysiology == | ||
The shoulder pad sign occurs due to the deposition of amyloid proteins in the soft tissues around the shoulders. Amyloid is an abnormal protein that can accumulate in various tissues and organs, leading to dysfunction. In the case of the shoulder pad sign, the amyloid deposits cause a noticeable swelling over the shoulders, which can be palpated and sometimes seen as a bulging mass. | The shoulder pad sign occurs due to the deposition of amyloid proteins in the soft tissues around the shoulders. Amyloid is an abnormal protein that can accumulate in various tissues and organs, leading to dysfunction. In the case of the shoulder pad sign, the amyloid deposits cause a noticeable swelling over the shoulders, which can be palpated and sometimes seen as a bulging mass. | ||
== Clinical significance == | == Clinical significance == | ||
The presence of the shoulder pad sign is a significant clinical indicator of systemic amyloidosis. It is important for clinicians to recognize this sign as it can aid in the early diagnosis of amyloidosis, which is crucial for the management and treatment of the condition. The shoulder pad sign is not exclusive to amyloidosis but is highly suggestive of it, especially when accompanied by other symptoms such as [[carpal tunnel syndrome]], [[macroglossia]], and [[nephrotic syndrome]]. | The presence of the shoulder pad sign is a significant clinical indicator of systemic amyloidosis. It is important for clinicians to recognize this sign as it can aid in the early diagnosis of amyloidosis, which is crucial for the management and treatment of the condition. The shoulder pad sign is not exclusive to amyloidosis but is highly suggestive of it, especially when accompanied by other symptoms such as [[carpal tunnel syndrome]], [[macroglossia]], and [[nephrotic syndrome]]. | ||
== Diagnosis == | == Diagnosis == | ||
The diagnosis of amyloidosis in the presence of the shoulder pad sign involves a combination of clinical evaluation, laboratory tests, and imaging studies. A biopsy of the affected tissue, stained with [[Congo red stain]], can confirm the presence of amyloid deposits. Additional tests may include serum and urine protein electrophoresis, immunofixation, and genetic testing to determine the type of amyloidosis. | The diagnosis of amyloidosis in the presence of the shoulder pad sign involves a combination of clinical evaluation, laboratory tests, and imaging studies. A biopsy of the affected tissue, stained with [[Congo red stain]], can confirm the presence of amyloid deposits. Additional tests may include serum and urine protein electrophoresis, immunofixation, and genetic testing to determine the type of amyloidosis. | ||
== Treatment == | == Treatment == | ||
Treatment of amyloidosis with the shoulder pad sign focuses on managing the underlying cause of amyloid deposition. In primary amyloidosis, treatment options may include chemotherapy, autologous stem cell transplantation, and novel agents such as proteasome inhibitors and monoclonal antibodies. Supportive care is also important to manage symptoms and improve quality of life. | Treatment of amyloidosis with the shoulder pad sign focuses on managing the underlying cause of amyloid deposition. In primary amyloidosis, treatment options may include chemotherapy, autologous stem cell transplantation, and novel agents such as proteasome inhibitors and monoclonal antibodies. Supportive care is also important to manage symptoms and improve quality of life. | ||
== See Also == | |||
== | |||
* [[Amyloidosis]] | * [[Amyloidosis]] | ||
* [[Primary amyloidosis]] | * [[Primary amyloidosis]] | ||
| Line 24: | Line 29: | ||
* [[Macroglossia]] | * [[Macroglossia]] | ||
* [[Nephrotic syndrome]] | * [[Nephrotic syndrome]] | ||
[[Category:Medical signs]] | [[Category:Medical signs]] | ||
[[Category:Amyloidosis]] | [[Category:Amyloidosis]] | ||
Latest revision as of 07:29, 6 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Shoulder pad sign | |
|---|---|
| |
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | Rheumatology, Oncology |
| Symptoms | Swelling over the shoulder area |
| Complications | N/A |
| Onset | N/A |
| Duration | N/A |
| Types | N/A |
| Causes | Primary amyloidosis, Multiple myeloma |
| Risks | N/A |
| Diagnosis | Physical examination, Imaging studies, Biopsy |
| Differential diagnosis | Lipoma, Lymphoma, Soft tissue sarcoma |
| Prevention | N/A |
| Treatment | Depends on underlying cause; may include chemotherapy, radiation therapy, or surgical intervention |
| Medication | N/A |
| Prognosis | Varies based on underlying condition |
| Frequency | Rare |
| Deaths | N/A |
Clinical sign in medicine
The shoulder pad sign is a clinical manifestation characterized by the presence of soft tissue swelling over the shoulders, giving the appearance of shoulder pads. This sign is most commonly associated with amyloidosis, particularly primary amyloidosis (AL amyloidosis), where there is deposition of amyloid protein in the soft tissues.
Pathophysiology[edit]
The shoulder pad sign occurs due to the deposition of amyloid proteins in the soft tissues around the shoulders. Amyloid is an abnormal protein that can accumulate in various tissues and organs, leading to dysfunction. In the case of the shoulder pad sign, the amyloid deposits cause a noticeable swelling over the shoulders, which can be palpated and sometimes seen as a bulging mass.
Clinical significance[edit]
The presence of the shoulder pad sign is a significant clinical indicator of systemic amyloidosis. It is important for clinicians to recognize this sign as it can aid in the early diagnosis of amyloidosis, which is crucial for the management and treatment of the condition. The shoulder pad sign is not exclusive to amyloidosis but is highly suggestive of it, especially when accompanied by other symptoms such as carpal tunnel syndrome, macroglossia, and nephrotic syndrome.
Diagnosis[edit]
The diagnosis of amyloidosis in the presence of the shoulder pad sign involves a combination of clinical evaluation, laboratory tests, and imaging studies. A biopsy of the affected tissue, stained with Congo red stain, can confirm the presence of amyloid deposits. Additional tests may include serum and urine protein electrophoresis, immunofixation, and genetic testing to determine the type of amyloidosis.
Treatment[edit]
Treatment of amyloidosis with the shoulder pad sign focuses on managing the underlying cause of amyloid deposition. In primary amyloidosis, treatment options may include chemotherapy, autologous stem cell transplantation, and novel agents such as proteasome inhibitors and monoclonal antibodies. Supportive care is also important to manage symptoms and improve quality of life.
