Cocaine intoxication: Difference between revisions

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{{SI}}
{{Infobox medical condition
| name            = Cocaine intoxication
| image          = [[File:Kokain_-_Cocaine.svg|left|thumb|Cocaine]]
| caption        = Cocaine
| field          = [[Toxicology]], [[Emergency medicine]]
| symptoms        = [[Euphoria]], [[agitation]], [[tachycardia]], [[hypertension]], [[dilated pupils]], [[hyperthermia]], [[seizures]]
| complications  = [[Myocardial infarction]], [[stroke]], [[rhabdomyolysis]], [[cardiac arrest]]
| onset          = Minutes after use
| duration        = Several hours
| causes          = Use of [[cocaine]]
| risks          = [[High blood pressure]], [[heart disease]], [[mental health disorders]]
| diagnosis      = Based on [[history of use]] and [[clinical presentation]]
| differential    = [[Amphetamine intoxication]], [[serotonin syndrome]], [[anticholinergic toxicity]]
| prevention      = Avoidance of cocaine use
| treatment      = [[Benzodiazepines]], [[supportive care]], [[cooling measures]]
| prognosis      = Variable; can be fatal if untreated
| frequency      = Common among cocaine users
}}
= Cocaine Intoxication =
= Cocaine Intoxication =
'''Cocaine intoxication''' refers to the complex range of subjective and physiological effects induced by cocaine, a powerful stimulant drug. This condition encompasses both the sought-after euphoric effects by users and the potentially harmful adverse effects on an individual's mind and behavior. Cocaine intoxication can occur through both voluntary and involuntary exposure to the drug, carrying significant medical and legal consequences. While some effects may be immediate and acute, others may develop into chronic conditions with repeated use. Even a single episode of cocaine use can lead to severe acute intoxication, emphasizing the drug's potent nature.
'''Cocaine intoxication''' refers to the complex range of subjective and physiological effects induced by cocaine, a powerful stimulant drug. This condition encompasses both the sought-after euphoric effects by users and the potentially harmful adverse effects on an individual's mind and behavior. Cocaine intoxication can occur through both voluntary and involuntary exposure to the drug, carrying significant medical and legal consequences. While some effects may be immediate and acute, others may develop into chronic conditions with repeated use. Even a single episode of cocaine use can lead to severe acute intoxication, emphasizing the drug's potent nature.
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== Introduction ==
== Introduction ==
Cocaine, extracted from the coca plant, has been used for centuries for its stimulant properties. In modern times, it is recognized for its potential to cause significant psychological and physical harm. Cocaine intoxication presents a major challenge to healthcare systems worldwide due to its immediate impact on the cardiovascular system, potential for addiction, and association with various psychiatric and medical complications.
Cocaine, extracted from the coca plant, has been used for centuries for its stimulant properties. In modern times, it is recognized for its potential to cause significant psychological and physical harm. Cocaine intoxication presents a major challenge to healthcare systems worldwide due to its immediate impact on the cardiovascular system, potential for addiction, and association with various psychiatric and medical complications.
 
[[File:CocaineHydrochloridePowder.jpg|left|thumb|Cocaine hydrochloride powder, commonly abused for its euphoric effects.]]
[[File:CocaineHydrochloridePowder.jpg|thumb|Cocaine hydrochloride powder, commonly abused for its euphoric effects.]]
 
== Effects of Cocaine ==
== Effects of Cocaine ==
Cocaine acts by blocking the reuptake of dopamine, serotonin, and norepinephrine in the brain, leading to increased concentrations of these neurotransmitters. The result is a heightened state of alertness, feelings of well-being, increased energy, and sociability. However, these effects come at a cost, including potential for heart attacks, stroke, and mental health disorders.
Cocaine acts by blocking the reuptake of dopamine, serotonin, and norepinephrine in the brain, leading to increased concentrations of these neurotransmitters. The result is a heightened state of alertness, feelings of well-being, increased energy, and sociability. However, these effects come at a cost, including potential for heart attacks, stroke, and mental health disorders.
== Signs of Cocaine Intoxication ==
== Signs of Cocaine Intoxication ==
Recognizing cocaine intoxication involves observing several key signs and symptoms:
Recognizing cocaine intoxication involves observing several key signs and symptoms:
* Increased heart rate and blood pressure
* Increased heart rate and blood pressure
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* Agitation or anxiety
* Agitation or anxiety
* Paranoid ideation
* Paranoid ideation
== Acute and Chronic Complications ==
== Acute and Chronic Complications ==
Acute complications can include cardiac arrhythmias, myocardial infarction, and seizures. Chronic use of cocaine can lead to addiction, nasal septum damage, and long-term cognitive impairments, among other health issues.
Acute complications can include cardiac arrhythmias, myocardial infarction, and seizures. Chronic use of cocaine can lead to addiction, nasal septum damage, and long-term cognitive impairments, among other health issues.
== Medical and Legal Implications ==
== Medical and Legal Implications ==
Both self-induced and involuntary exposure to cocaine have significant implications. Medically, cocaine intoxication requires immediate attention to prevent potentially life-threatening conditions. Legally, possession and distribution of cocaine are crimes in many jurisdictions, and driving or operating machinery under the influence can result in severe penalties.
Both self-induced and involuntary exposure to cocaine have significant implications. Medically, cocaine intoxication requires immediate attention to prevent potentially life-threatening conditions. Legally, possession and distribution of cocaine are crimes in many jurisdictions, and driving or operating machinery under the influence can result in severe penalties.
== Prevention and Treatment ==
== Prevention and Treatment ==
Preventing cocaine intoxication involves public education, access to addiction treatment services, and support for at-risk populations. Treatment for cocaine intoxication may include acute care for overdose symptoms and long-term strategies for addiction management, including behavioral therapy and support groups.
Preventing cocaine intoxication involves public education, access to addiction treatment services, and support for at-risk populations. Treatment for cocaine intoxication may include acute care for overdose symptoms and long-term strategies for addiction management, including behavioral therapy and support groups.
== See Also ==
== See Also ==
* [[Substance abuse]]
* [[Substance abuse]]
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* [[Addiction psychiatry]]
* [[Addiction psychiatry]]
* [[Cardiovascular complications of drugs]]
* [[Cardiovascular complications of drugs]]
== External Links ==
== External Links ==
* [https://www.who.int/substance_abuse/facts/cocaine/en/ World Health Organization - Cocaine]
* [https://www.who.int/substance_abuse/facts/cocaine/en/ World Health Organization - Cocaine]
* [https://www.drugabuse.gov/publications/drugfacts/cocaine National Institute on Drug Abuse - Cocaine]
* [https://www.drugabuse.gov/publications/drugfacts/cocaine National Institute on Drug Abuse - Cocaine]
== References ==
== References ==
<references/>
<references/>
* "Cocaine Intoxication: Clinical Features, Diagnosis, and Treatment." Clinical Pharmacology & Therapeutics.
* "Cocaine Intoxication: Clinical Features, Diagnosis, and Treatment." Clinical Pharmacology & Therapeutics.
* "The Neurobiology of Cocaine Addiction." Science Advances.
* "The Neurobiology of Cocaine Addiction." Science Advances.
[[Category:Drug abuse]]
[[Category:Drug abuse]]
[[Category:Cocaine]]
[[Category:Cocaine]]
[[Category:Toxicology]]
[[Category:Toxicology]]
[[Category:Emergency medicine]]
[[Category:Emergency medicine]]
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Latest revision as of 02:01, 5 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's medical weight loss NYC, sleep center NYC
Philadelphia medical weight loss and Philadelphia sleep clinics

Cocaine intoxication
Cocaine
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Euphoria, agitation, tachycardia, hypertension, dilated pupils, hyperthermia, seizures
Complications Myocardial infarction, stroke, rhabdomyolysis, cardiac arrest
Onset Minutes after use
Duration Several hours
Types N/A
Causes Use of cocaine
Risks High blood pressure, heart disease, mental health disorders
Diagnosis Based on history of use and clinical presentation
Differential diagnosis Amphetamine intoxication, serotonin syndrome, anticholinergic toxicity
Prevention Avoidance of cocaine use
Treatment Benzodiazepines, supportive care, cooling measures
Medication N/A
Prognosis Variable; can be fatal if untreated
Frequency Common among cocaine users
Deaths N/A


Cocaine Intoxication[edit]

Cocaine intoxication refers to the complex range of subjective and physiological effects induced by cocaine, a powerful stimulant drug. This condition encompasses both the sought-after euphoric effects by users and the potentially harmful adverse effects on an individual's mind and behavior. Cocaine intoxication can occur through both voluntary and involuntary exposure to the drug, carrying significant medical and legal consequences. While some effects may be immediate and acute, others may develop into chronic conditions with repeated use. Even a single episode of cocaine use can lead to severe acute intoxication, emphasizing the drug's potent nature.

Introduction[edit]

Cocaine, extracted from the coca plant, has been used for centuries for its stimulant properties. In modern times, it is recognized for its potential to cause significant psychological and physical harm. Cocaine intoxication presents a major challenge to healthcare systems worldwide due to its immediate impact on the cardiovascular system, potential for addiction, and association with various psychiatric and medical complications.

Cocaine hydrochloride powder, commonly abused for its euphoric effects.

Effects of Cocaine[edit]

Cocaine acts by blocking the reuptake of dopamine, serotonin, and norepinephrine in the brain, leading to increased concentrations of these neurotransmitters. The result is a heightened state of alertness, feelings of well-being, increased energy, and sociability. However, these effects come at a cost, including potential for heart attacks, stroke, and mental health disorders.

Signs of Cocaine Intoxication[edit]

Recognizing cocaine intoxication involves observing several key signs and symptoms:

  • Increased heart rate and blood pressure
  • Dilated pupils
  • Elevated body temperature
  • Excessive euphoria
  • Agitation or anxiety
  • Paranoid ideation

Acute and Chronic Complications[edit]

Acute complications can include cardiac arrhythmias, myocardial infarction, and seizures. Chronic use of cocaine can lead to addiction, nasal septum damage, and long-term cognitive impairments, among other health issues.

Medical and Legal Implications[edit]

Both self-induced and involuntary exposure to cocaine have significant implications. Medically, cocaine intoxication requires immediate attention to prevent potentially life-threatening conditions. Legally, possession and distribution of cocaine are crimes in many jurisdictions, and driving or operating machinery under the influence can result in severe penalties.

Prevention and Treatment[edit]

Preventing cocaine intoxication involves public education, access to addiction treatment services, and support for at-risk populations. Treatment for cocaine intoxication may include acute care for overdose symptoms and long-term strategies for addiction management, including behavioral therapy and support groups.

See Also[edit]

External Links[edit]

References[edit]

<references/>

  • "Cocaine Intoxication: Clinical Features, Diagnosis, and Treatment." Clinical Pharmacology & Therapeutics.
  • "The Neurobiology of Cocaine Addiction." Science Advances.
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