Arteriosclerosis obliterans: Difference between revisions
From WikiMD's Wellness Encyclopedia
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{{Infobox medical condition | |||
| name = Arteriosclerosis obliterans | |||
| image = [[File:Gray531.png|250px]] | |||
| caption = Diagram of an artery showing arteriosclerosis | |||
| synonyms = [[Peripheral artery disease]], [[peripheral vascular disease]] | |||
| specialty = [[Vascular surgery]], [[Cardiology]] | |||
| symptoms = [[Claudication]], [[leg pain]], [[cold feet]], [[ulcers]] | |||
| complications = [[Gangrene]], [[amputation]], [[heart attack]], [[stroke]] | |||
| onset = Typically after age 50 | |||
| duration = Long-term | |||
| causes = [[Atherosclerosis]], [[smoking]], [[diabetes]], [[hypertension]], [[high cholesterol]] | |||
| risks = [[Smoking]], [[diabetes]], [[high blood pressure]], [[high cholesterol]], [[obesity]] | |||
| diagnosis = [[Ankle-brachial index]], [[Doppler ultrasound]], [[angiography]] | |||
| differential = [[Deep vein thrombosis]], [[spinal stenosis]], [[arthritis]] | |||
| prevention = [[Smoking cessation]], [[exercise]], [[healthy diet]], [[cholesterol management]] | |||
| treatment = [[Lifestyle changes]], [[medications]], [[angioplasty]], [[bypass surgery]] | |||
| medication = [[Statins]], [[antiplatelet drugs]], [[cilostazol]] | |||
| prognosis = Variable, depends on severity and treatment | |||
| frequency = Common in older adults | |||
}} | |||
{{Short description|A condition characterized by the thickening and hardening of the walls of the arteries, leading to reduced blood flow.}} | {{Short description|A condition characterized by the thickening and hardening of the walls of the arteries, leading to reduced blood flow.}} | ||
== Arteriosclerosis Obliterans == | == Arteriosclerosis Obliterans == | ||
[[File:Gray531.png|thumb | [[File:Gray531.png|left|thumb|Diagram of an artery showing arteriosclerosis.]] | ||
'''Arteriosclerosis obliterans''' is a form of [[arteriosclerosis]] involving the progressive thickening and hardening of the walls of the arteries. This condition leads to the narrowing and eventual blockage of the arteries, which can significantly reduce blood flow to various parts of the body. | '''Arteriosclerosis obliterans''' is a form of [[arteriosclerosis]] involving the progressive thickening and hardening of the walls of the arteries. This condition leads to the narrowing and eventual blockage of the arteries, which can significantly reduce blood flow to various parts of the body. | ||
== Pathophysiology == | == Pathophysiology == | ||
Arteriosclerosis obliterans primarily affects the [[peripheral arteries]], particularly those supplying the [[lower extremities]]. The disease process involves the buildup of [[atherosclerotic plaques]] within the arterial walls. These plaques are composed of [[lipids]], [[calcium]], and other substances found in the blood. Over time, the plaques harden and narrow the arterial lumen, impeding blood flow. | Arteriosclerosis obliterans primarily affects the [[peripheral arteries]], particularly those supplying the [[lower extremities]]. The disease process involves the buildup of [[atherosclerotic plaques]] within the arterial walls. These plaques are composed of [[lipids]], [[calcium]], and other substances found in the blood. Over time, the plaques harden and narrow the arterial lumen, impeding blood flow. | ||
== Clinical Manifestations == | == Clinical Manifestations == | ||
The symptoms of arteriosclerosis obliterans depend on the severity and location of the arterial blockage. Common symptoms include: | The symptoms of arteriosclerosis obliterans depend on the severity and location of the arterial blockage. Common symptoms include: | ||
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* [[Rest pain]]: Persistent pain in the feet or toes, especially at night. | * [[Rest pain]]: Persistent pain in the feet or toes, especially at night. | ||
* [[Ulceration]] and [[gangrene]]: Severe cases may lead to tissue death due to lack of blood supply. | * [[Ulceration]] and [[gangrene]]: Severe cases may lead to tissue death due to lack of blood supply. | ||
== Diagnosis == | == Diagnosis == | ||
The diagnosis of arteriosclerosis obliterans is typically made through a combination of clinical evaluation and diagnostic tests. These may include: | The diagnosis of arteriosclerosis obliterans is typically made through a combination of clinical evaluation and diagnostic tests. These may include: | ||
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* [[Doppler ultrasound]]: To assess blood flow in the arteries. | * [[Doppler ultrasound]]: To assess blood flow in the arteries. | ||
* [[Angiography]]: Imaging technique to visualize the arteries and identify blockages. | * [[Angiography]]: Imaging technique to visualize the arteries and identify blockages. | ||
== Treatment == | == Treatment == | ||
Treatment for arteriosclerosis obliterans aims to relieve symptoms and prevent further progression of the disease. Options include: | Treatment for arteriosclerosis obliterans aims to relieve symptoms and prevent further progression of the disease. Options include: | ||
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* [[Medications]]: Such as [[antiplatelet agents]], [[statins]], and [[vasodilators]]. | * [[Medications]]: Such as [[antiplatelet agents]], [[statins]], and [[vasodilators]]. | ||
* [[Surgical interventions]]: Including [[angioplasty]], [[stenting]], or [[bypass surgery]] for severe cases. | * [[Surgical interventions]]: Including [[angioplasty]], [[stenting]], or [[bypass surgery]] for severe cases. | ||
== Prevention == | == Prevention == | ||
Preventive measures focus on reducing risk factors associated with arteriosclerosis. These include: | Preventive measures focus on reducing risk factors associated with arteriosclerosis. These include: | ||
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* Regular physical activity. | * Regular physical activity. | ||
* Controlling [[hypertension]], [[diabetes]], and [[hyperlipidemia]]. | * Controlling [[hypertension]], [[diabetes]], and [[hyperlipidemia]]. | ||
== See also == | |||
== | |||
* [[Atherosclerosis]] | * [[Atherosclerosis]] | ||
* [[Peripheral artery disease]] | * [[Peripheral artery disease]] | ||
* [[Cardiovascular disease]] | * [[Cardiovascular disease]] | ||
[[Category:Vascular diseases]] | [[Category:Vascular diseases]] | ||
[[Category:Cardiovascular diseases]] | [[Category:Cardiovascular diseases]] | ||
Latest revision as of 16:54, 4 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Arteriosclerosis obliterans | |
|---|---|
| |
| Synonyms | Peripheral artery disease, peripheral vascular disease |
| Pronounce | N/A |
| Specialty | Vascular surgery, Cardiology |
| Symptoms | Claudication, leg pain, cold feet, ulcers |
| Complications | Gangrene, amputation, heart attack, stroke |
| Onset | Typically after age 50 |
| Duration | Long-term |
| Types | N/A |
| Causes | Atherosclerosis, smoking, diabetes, hypertension, high cholesterol |
| Risks | Smoking, diabetes, high blood pressure, high cholesterol, obesity |
| Diagnosis | Ankle-brachial index, Doppler ultrasound, angiography |
| Differential diagnosis | Deep vein thrombosis, spinal stenosis, arthritis |
| Prevention | Smoking cessation, exercise, healthy diet, cholesterol management |
| Treatment | Lifestyle changes, medications, angioplasty, bypass surgery |
| Medication | Statins, antiplatelet drugs, cilostazol |
| Prognosis | Variable, depends on severity and treatment |
| Frequency | Common in older adults |
| Deaths | N/A |
A condition characterized by the thickening and hardening of the walls of the arteries, leading to reduced blood flow.
Arteriosclerosis Obliterans[edit]
Arteriosclerosis obliterans is a form of arteriosclerosis involving the progressive thickening and hardening of the walls of the arteries. This condition leads to the narrowing and eventual blockage of the arteries, which can significantly reduce blood flow to various parts of the body.
Pathophysiology[edit]
Arteriosclerosis obliterans primarily affects the peripheral arteries, particularly those supplying the lower extremities. The disease process involves the buildup of atherosclerotic plaques within the arterial walls. These plaques are composed of lipids, calcium, and other substances found in the blood. Over time, the plaques harden and narrow the arterial lumen, impeding blood flow.
Clinical Manifestations[edit]
The symptoms of arteriosclerosis obliterans depend on the severity and location of the arterial blockage. Common symptoms include:
- Intermittent claudication: Pain and cramping in the legs during exercise, which is relieved by rest.
- Rest pain: Persistent pain in the feet or toes, especially at night.
- Ulceration and gangrene: Severe cases may lead to tissue death due to lack of blood supply.
Diagnosis[edit]
The diagnosis of arteriosclerosis obliterans is typically made through a combination of clinical evaluation and diagnostic tests. These may include:
- Ankle-brachial index (ABI): A simple test comparing blood pressure in the ankle and arm.
- Doppler ultrasound: To assess blood flow in the arteries.
- Angiography: Imaging technique to visualize the arteries and identify blockages.
Treatment[edit]
Treatment for arteriosclerosis obliterans aims to relieve symptoms and prevent further progression of the disease. Options include:
- Lifestyle modifications: Smoking cessation, exercise, and dietary changes.
- Medications: Such as antiplatelet agents, statins, and vasodilators.
- Surgical interventions: Including angioplasty, stenting, or bypass surgery for severe cases.
Prevention[edit]
Preventive measures focus on reducing risk factors associated with arteriosclerosis. These include:
- Maintaining a healthy diet low in saturated fats and cholesterol.
- Regular physical activity.
- Controlling hypertension, diabetes, and hyperlipidemia.
