Congenital cutaneous candidiasis: Difference between revisions

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{{Infobox medical condition
| name            = Congenital cutaneous candidiasis
| synonyms        = Neonatal candidiasis
| field          = [[Dermatology]], [[Pediatrics]]
| symptoms        = [[Rash]], [[erythema]], [[pustules]], [[scaling]]
| complications  = [[Systemic candidiasis]], [[sepsis]]
| onset          = At birth or within the first few days of life
| duration        = Varies, typically resolves with treatment
| causes          = [[Candida albicans]] infection
| risks          = [[Premature birth]], [[prolonged rupture of membranes]], [[maternal vaginal candidiasis]]
| diagnosis      = [[Clinical examination]], [[skin culture]], [[microscopy]]
| differential    = [[Neonatal herpes simplex]], [[impetigo]], [[staphylococcal scalded skin syndrome]]
| prevention      = Treating maternal [[vaginal candidiasis]] during pregnancy
| treatment      = [[Topical antifungal]]s, [[oral antifungal]]s if severe
| medication      = [[Nystatin]], [[Clotrimazole]], [[Fluconazole]]
| prognosis      = Good with treatment
| frequency      = Rare
}}
'''Congenital cutaneous candidiasis''' is a rare and severe [[infection]] that affects newborns. It is caused by the [[Candida]] species, a type of [[fungus]]. The infection is present at birth and is characterized by widespread skin lesions.
'''Congenital cutaneous candidiasis''' is a rare and severe [[infection]] that affects newborns. It is caused by the [[Candida]] species, a type of [[fungus]]. The infection is present at birth and is characterized by widespread skin lesions.
==Etiology==
==Etiology==
The primary cause of congenital cutaneous candidiasis is the Candida species, particularly [[Candida albicans]]. The infection is acquired in utero, meaning it is passed from the mother to the fetus during pregnancy. The Candida species is a common inhabitant of the human body, particularly in the [[gastrointestinal tract]] and the female [[genital tract]]. However, it can cause disease when the body's immune system is compromised or when the normal balance of microorganisms is disrupted.
The primary cause of congenital cutaneous candidiasis is the Candida species, particularly [[Candida albicans]]. The infection is acquired in utero, meaning it is passed from the mother to the fetus during pregnancy. The Candida species is a common inhabitant of the human body, particularly in the [[gastrointestinal tract]] and the female [[genital tract]]. However, it can cause disease when the body's immune system is compromised or when the normal balance of microorganisms is disrupted.
==Clinical Presentation==
==Clinical Presentation==
Newborns with congenital cutaneous candidiasis present with widespread skin lesions at birth. These lesions are typically pustular and may be accompanied by other symptoms such as [[fever]], irritability, and poor feeding. In severe cases, the infection can spread to other organs and cause systemic disease.
Newborns with congenital cutaneous candidiasis present with widespread skin lesions at birth. These lesions are typically pustular and may be accompanied by other symptoms such as [[fever]], irritability, and poor feeding. In severe cases, the infection can spread to other organs and cause systemic disease.
==Diagnosis==
==Diagnosis==
Diagnosis of congenital cutaneous candidiasis is based on clinical presentation and confirmed by laboratory tests. The Candida species can be isolated from skin lesions, blood, or other body fluids. [[Microscopy]] and culture are the most common laboratory methods used to identify the Candida species.
Diagnosis of congenital cutaneous candidiasis is based on clinical presentation and confirmed by laboratory tests. The Candida species can be isolated from skin lesions, blood, or other body fluids. [[Microscopy]] and culture are the most common laboratory methods used to identify the Candida species.
==Treatment==
==Treatment==
Treatment for congenital cutaneous candidiasis involves antifungal therapy. The most commonly used antifungal drugs are [[amphotericin B]] and [[fluconazole]]. In severe cases, systemic therapy may be required.
Treatment for congenital cutaneous candidiasis involves antifungal therapy. The most commonly used antifungal drugs are [[amphotericin B]] and [[fluconazole]]. In severe cases, systemic therapy may be required.
==Prognosis==
==Prognosis==
The prognosis for congenital cutaneous candidiasis is generally good with appropriate treatment. However, if the infection spreads to other organs, it can be life-threatening.
The prognosis for congenital cutaneous candidiasis is generally good with appropriate treatment. However, if the infection spreads to other organs, it can be life-threatening.
==Prevention==
==Prevention==
Prevention of congenital cutaneous candidiasis involves controlling the Candida species in pregnant women. This can be achieved through good hygiene practices and the use of antifungal drugs if necessary.
Prevention of congenital cutaneous candidiasis involves controlling the Candida species in pregnant women. This can be achieved through good hygiene practices and the use of antifungal drugs if necessary.
[[Category:Infections]]
[[Category:Infections]]
[[Category:Newborn health]]
[[Category:Newborn health]]
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{{Pediatrics-stub}}
{{Pediatrics-stub}}
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Latest revision as of 05:32, 4 April 2025


Congenital cutaneous candidiasis
Synonyms Neonatal candidiasis
Pronounce N/A
Specialty N/A
Symptoms Rash, erythema, pustules, scaling
Complications Systemic candidiasis, sepsis
Onset At birth or within the first few days of life
Duration Varies, typically resolves with treatment
Types N/A
Causes Candida albicans infection
Risks Premature birth, prolonged rupture of membranes, maternal vaginal candidiasis
Diagnosis Clinical examination, skin culture, microscopy
Differential diagnosis Neonatal herpes simplex, impetigo, staphylococcal scalded skin syndrome
Prevention Treating maternal vaginal candidiasis during pregnancy
Treatment Topical antifungals, oral antifungals if severe
Medication Nystatin, Clotrimazole, Fluconazole
Prognosis Good with treatment
Frequency Rare
Deaths N/A


Congenital cutaneous candidiasis is a rare and severe infection that affects newborns. It is caused by the Candida species, a type of fungus. The infection is present at birth and is characterized by widespread skin lesions.

Etiology[edit]

The primary cause of congenital cutaneous candidiasis is the Candida species, particularly Candida albicans. The infection is acquired in utero, meaning it is passed from the mother to the fetus during pregnancy. The Candida species is a common inhabitant of the human body, particularly in the gastrointestinal tract and the female genital tract. However, it can cause disease when the body's immune system is compromised or when the normal balance of microorganisms is disrupted.

Clinical Presentation[edit]

Newborns with congenital cutaneous candidiasis present with widespread skin lesions at birth. These lesions are typically pustular and may be accompanied by other symptoms such as fever, irritability, and poor feeding. In severe cases, the infection can spread to other organs and cause systemic disease.

Diagnosis[edit]

Diagnosis of congenital cutaneous candidiasis is based on clinical presentation and confirmed by laboratory tests. The Candida species can be isolated from skin lesions, blood, or other body fluids. Microscopy and culture are the most common laboratory methods used to identify the Candida species.

Treatment[edit]

Treatment for congenital cutaneous candidiasis involves antifungal therapy. The most commonly used antifungal drugs are amphotericin B and fluconazole. In severe cases, systemic therapy may be required.

Prognosis[edit]

The prognosis for congenital cutaneous candidiasis is generally good with appropriate treatment. However, if the infection spreads to other organs, it can be life-threatening.

Prevention[edit]

Prevention of congenital cutaneous candidiasis involves controlling the Candida species in pregnant women. This can be achieved through good hygiene practices and the use of antifungal drugs if necessary.


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