Steroid-induced osteoporosis: Difference between revisions
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{{Infobox medical condition | |||
| name = Steroid-induced osteoporosis | |||
| synonyms = Glucocorticoid-induced osteoporosis | |||
| field = [[Endocrinology]], [[Rheumatology]] | |||
| symptoms = [[Bone fracture]], [[Back pain]], [[Loss of height]] | |||
| complications = [[Fracture]], [[Kyphosis]] | |||
| onset = After prolonged use of [[glucocorticoids]] | |||
| duration = Chronic | |||
| causes = Long-term use of [[glucocorticoids]] | |||
| risks = High-dose [[glucocorticoid]] therapy, [[postmenopausal]] women, [[elderly]] | |||
| diagnosis = [[Bone mineral density]] test, [[Dual-energy X-ray absorptiometry]] (DEXA) | |||
| differential = [[Osteoporosis]], [[Osteomalacia]], [[Hyperparathyroidism]] | |||
| prevention = [[Calcium]] and [[vitamin D]] supplementation, [[bisphosphonates]] | |||
| treatment = [[Bisphosphonates]], [[Teriparatide]], [[Denosumab]] | |||
| medication = [[Alendronate]], [[Risedronate]], [[Zoledronic acid]] | |||
| prognosis = Variable, depends on management and reduction of [[glucocorticoid]] use | |||
| frequency = Common in patients on long-term [[glucocorticoid]] therapy | |||
}} | |||
'''Steroid-induced osteoporosis''' is a form of [[osteoporosis]] which is caused by long-term use of [[glucocorticoids]], also known as steroids. This condition is characterized by a decrease in bone density, which can lead to an increased risk of [[bone fracture]]s. | '''Steroid-induced osteoporosis''' is a form of [[osteoporosis]] which is caused by long-term use of [[glucocorticoids]], also known as steroids. This condition is characterized by a decrease in bone density, which can lead to an increased risk of [[bone fracture]]s. | ||
== Causes == | == Causes == | ||
Steroid-induced osteoporosis can occur as a side effect of long-term treatment with glucocorticoids. These medications are often used to treat conditions such as [[rheumatoid arthritis]], [[lupus]], and [[asthma]]. The risk of developing this condition increases with the duration of glucocorticoid use and the dosage taken. | Steroid-induced osteoporosis can occur as a side effect of long-term treatment with glucocorticoids. These medications are often used to treat conditions such as [[rheumatoid arthritis]], [[lupus]], and [[asthma]]. The risk of developing this condition increases with the duration of glucocorticoid use and the dosage taken. | ||
== Symptoms == | == Symptoms == | ||
The symptoms of steroid-induced osteoporosis are similar to those of other forms of osteoporosis. They can include: | The symptoms of steroid-induced osteoporosis are similar to those of other forms of osteoporosis. They can include: | ||
* [[Back pain]] | * [[Back pain]] | ||
* Loss of height over time | * Loss of height over time | ||
* A stooped posture | * A stooped posture | ||
* An increased risk of bone fractures, especially in the spine, hip, and wrist | * An increased risk of bone fractures, especially in the spine, hip, and wrist | ||
== Diagnosis == | == Diagnosis == | ||
The diagnosis of steroid-induced osteoporosis is typically made based on a combination of a patient's medical history, physical examination, and bone density testing. The most commonly used test is a type of X-ray known as a [[dual-energy X-ray absorptiometry]] (DEXA) scan. | The diagnosis of steroid-induced osteoporosis is typically made based on a combination of a patient's medical history, physical examination, and bone density testing. The most commonly used test is a type of X-ray known as a [[dual-energy X-ray absorptiometry]] (DEXA) scan. | ||
== Treatment == | == Treatment == | ||
The treatment of steroid-induced osteoporosis typically involves a combination of medication and lifestyle changes. Medications can include [[bisphosphonates]], which help to slow the rate of bone loss, and [[calcium]] and [[vitamin D]] supplements, which can help to strengthen the bones. Lifestyle changes can include regular weight-bearing exercise and a diet rich in calcium and vitamin D. | The treatment of steroid-induced osteoporosis typically involves a combination of medication and lifestyle changes. Medications can include [[bisphosphonates]], which help to slow the rate of bone loss, and [[calcium]] and [[vitamin D]] supplements, which can help to strengthen the bones. Lifestyle changes can include regular weight-bearing exercise and a diet rich in calcium and vitamin D. | ||
== Prevention == | == Prevention == | ||
Prevention of steroid-induced osteoporosis can involve minimizing the use of glucocorticoids when possible, taking the lowest effective dose, and using other medications to control inflammation. Regular exercise and a healthy diet can also help to maintain bone health. | Prevention of steroid-induced osteoporosis can involve minimizing the use of glucocorticoids when possible, taking the lowest effective dose, and using other medications to control inflammation. Regular exercise and a healthy diet can also help to maintain bone health. | ||
== See also == | == See also == | ||
* [[Osteoporosis]] | * [[Osteoporosis]] | ||
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* [[Bone density]] | * [[Bone density]] | ||
* [[Bone fracture]] | * [[Bone fracture]] | ||
[[Category:Endocrine diseases]] | [[Category:Endocrine diseases]] | ||
[[Category:Bone diseases]] | [[Category:Bone diseases]] | ||
[[Category:Drug-induced diseases]] | [[Category:Drug-induced diseases]] | ||
{{stub}} | {{stub}} | ||
{{No image}} | {{No image}} | ||
Latest revision as of 03:00, 4 April 2025
| Steroid-induced osteoporosis | |
|---|---|
| Synonyms | Glucocorticoid-induced osteoporosis |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Bone fracture, Back pain, Loss of height |
| Complications | Fracture, Kyphosis |
| Onset | After prolonged use of glucocorticoids |
| Duration | Chronic |
| Types | N/A |
| Causes | Long-term use of glucocorticoids |
| Risks | High-dose glucocorticoid therapy, postmenopausal women, elderly |
| Diagnosis | Bone mineral density test, Dual-energy X-ray absorptiometry (DEXA) |
| Differential diagnosis | Osteoporosis, Osteomalacia, Hyperparathyroidism |
| Prevention | Calcium and vitamin D supplementation, bisphosphonates |
| Treatment | Bisphosphonates, Teriparatide, Denosumab |
| Medication | Alendronate, Risedronate, Zoledronic acid |
| Prognosis | Variable, depends on management and reduction of glucocorticoid use |
| Frequency | Common in patients on long-term glucocorticoid therapy |
| Deaths | N/A |
Steroid-induced osteoporosis is a form of osteoporosis which is caused by long-term use of glucocorticoids, also known as steroids. This condition is characterized by a decrease in bone density, which can lead to an increased risk of bone fractures.
Causes[edit]
Steroid-induced osteoporosis can occur as a side effect of long-term treatment with glucocorticoids. These medications are often used to treat conditions such as rheumatoid arthritis, lupus, and asthma. The risk of developing this condition increases with the duration of glucocorticoid use and the dosage taken.
Symptoms[edit]
The symptoms of steroid-induced osteoporosis are similar to those of other forms of osteoporosis. They can include:
- Back pain
- Loss of height over time
- A stooped posture
- An increased risk of bone fractures, especially in the spine, hip, and wrist
Diagnosis[edit]
The diagnosis of steroid-induced osteoporosis is typically made based on a combination of a patient's medical history, physical examination, and bone density testing. The most commonly used test is a type of X-ray known as a dual-energy X-ray absorptiometry (DEXA) scan.
Treatment[edit]
The treatment of steroid-induced osteoporosis typically involves a combination of medication and lifestyle changes. Medications can include bisphosphonates, which help to slow the rate of bone loss, and calcium and vitamin D supplements, which can help to strengthen the bones. Lifestyle changes can include regular weight-bearing exercise and a diet rich in calcium and vitamin D.
Prevention[edit]
Prevention of steroid-induced osteoporosis can involve minimizing the use of glucocorticoids when possible, taking the lowest effective dose, and using other medications to control inflammation. Regular exercise and a healthy diet can also help to maintain bone health.
