Zoledronic acid

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Zoledronic Acid

Zoledronic acid (pronounced zo-le-DRO-nik AS-id) is a type of bisphosphonate medication used to treat various bone diseases. It is marketed under the brand names Zometa and Reclast among others.

Pronunciation

Zoledronic acid is pronounced as zo-le-DRO-nik AS-id.

Etymology

The term "Zoledronic acid" is derived from the chemical name (1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene)bisphosphonic acid. The "Zoledronate" part of the name is a combination of parts of the chemical name.

Usage

Zoledronic acid is used to treat high blood calcium levels (hypercalcemia) that may occur with cancer. It is also used with cancer chemotherapy to treat bone problems that may occur with multiple myeloma and bone metastases from solid tumors. In addition, it is used to treat osteoporosis in postmenopausal women and men at high risk of fractures.

Mechanism of Action

Zoledronic acid works by slowing down the process of bone breakdown. It does this by binding to the mineral component of the bone and inhibiting the cells that break down bone (osteoclasts). This helps to maintain a healthy balance of bone formation and breakdown.

Related Terms

See Also

External links

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