Accelerated phase chronic myelogenous leukemia: Difference between revisions

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{{Infobox medical condition
| name                    = Accelerated phase chronic myelogenous leukemia
| synonyms                = Accelerated phase CML
| field                  = [[Hematology]]
| symptoms                = [[Fatigue (medical)]], [[fever]], [[weight loss]], [[splenomegaly]], [[bone pain]]
| complications          = [[Blast crisis]], [[anemia]], [[thrombocytopenia]]
| onset                  = Typically in [[middle age]]
| duration                = Chronic, with progression
| causes                  = [[Philadelphia chromosome]] (BCR-ABL1 fusion gene)
| risks                  = [[Radiation exposure]], [[genetic predisposition]]
| diagnosis              = [[Complete blood count]], [[bone marrow biopsy]], [[cytogenetic analysis]]
| differential            = [[Chronic myelogenous leukemia]], [[acute myeloid leukemia]], [[myelodysplastic syndrome]]
| treatment              = [[Tyrosine kinase inhibitors]], [[chemotherapy]], [[hematopoietic stem cell transplantation]]
| prognosis              = Variable, depends on response to treatment
| frequency              = Rare, as a phase of [[chronic myelogenous leukemia]]
}}
a phase of chronic myelogenous leukemia characterized by one or more of the following
a phase of chronic myelogenous leukemia characterized by one or more of the following
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Latest revision as of 22:26, 3 April 2025


Accelerated phase chronic myelogenous leukemia
Synonyms Accelerated phase CML
Pronounce N/A
Specialty N/A
Symptoms Fatigue (medical), fever, weight loss, splenomegaly, bone pain
Complications Blast crisis, anemia, thrombocytopenia
Onset Typically in middle age
Duration Chronic, with progression
Types N/A
Causes Philadelphia chromosome (BCR-ABL1 fusion gene)
Risks Radiation exposure, genetic predisposition
Diagnosis Complete blood count, bone marrow biopsy, cytogenetic analysis
Differential diagnosis Chronic myelogenous leukemia, acute myeloid leukemia, myelodysplastic syndrome
Prevention N/A
Treatment Tyrosine kinase inhibitors, chemotherapy, hematopoietic stem cell transplantation
Medication N/A
Prognosis Variable, depends on response to treatment
Frequency Rare, as a phase of chronic myelogenous leukemia
Deaths N/A


a phase of chronic myelogenous leukemia characterized by one or more of the following

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