PRCC

PRCC (Papillary Renal Cell Carcinoma) is a type of kidney cancer that originates in the lining of the proximal convoluted tubule, a part of the very small tubes in the kidney that transport primary urine. PRCC is the second most common type of renal cell carcinoma, accounting for approximately 10-15% of all cases.

Symptoms

The symptoms of PRCC are similar to those of other types of renal cell carcinoma. They may include:

• Blood in the urine (hematuria)
• A lump or mass in the kidney area
• Persistent pain in the side
• Unexplained weight loss
• Fatigue
• Fever that comes and goes
• Loss of appetite

Causes

The exact cause of PRCC is not known. However, it is believed to be associated with certain genetic mutations. PRCC is associated with the MET oncogene on chromosome 7, which is involved in cell growth and division.

Diagnosis

Diagnosis of PRCC typically involves a combination of physical examination, medical history, and imaging tests such as ultrasound, CT scan, or MRI. A biopsy may also be performed to confirm the diagnosis.

Treatment

Treatment options for PRCC depend on the stage of the disease, the patient's overall health, and other factors. They may include:

• Surgery to remove the tumor or the entire kidney
• Radiation therapy
• Chemotherapy
• Immunotherapy
• Targeted therapy

Prognosis

The prognosis for PRCC varies depending on the stage of the disease at diagnosis, the patient's overall health, and other factors. Early detection and treatment can improve the prognosis.

See also

• Renal cell carcinoma
• Kidney cancer
• Oncogene
• Biopsy
• Chemotherapy
• Radiation therapy
• Immunotherapy
• Targeted therapy

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