Inhalational anesthetic: Difference between revisions
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{{Short description|An overview of inhalational anesthetics used in medical practice}} | |||
== | == Inhalational Anesthetics == | ||
[[File:Fluranebottles.jpg|thumb|right|Bottles of common inhalational anesthetics]] | |||
Inhalational anesthetics are a class of [[anesthetic]] agents that are administered through the respiratory system. These agents are primarily used to induce and maintain [[general anesthesia]] during [[surgical procedures]]. They are delivered via a [[vaporizer]] and inhaled by the patient, allowing for rapid onset and easy control of the depth of anesthesia. | |||
==Mechanism of Action== | == Mechanism of Action == | ||
The exact mechanism | Inhalational anesthetics work by depressing the central nervous system, leading to a reversible loss of consciousness and sensation. The exact mechanism is not fully understood, but it is believed that these agents enhance the activity of inhibitory neurotransmitters such as [[gamma-aminobutyric acid]] (GABA) and inhibit excitatory neurotransmitters like [[glutamate]]. This results in decreased neuronal activity and altered synaptic transmission. | ||
== | == Common Inhalational Anesthetics == | ||
Several inhalational anesthetics are commonly used in clinical practice: | |||
* '''[[Isoflurane]]''': Known for its stability and minimal metabolism, isoflurane is widely used due to its favorable pharmacokinetic profile. | |||
* '''[[Sevoflurane]]''': Popular for its rapid induction and recovery times, sevoflurane is often used in outpatient procedures. | |||
* [[Isoflurane]] | * '''[[Desflurane]]''': Characterized by its low blood-gas solubility, desflurane allows for quick adjustments in anesthetic depth. | ||
* [[Sevoflurane]] | * '''[[Halothane]]''': Although less commonly used today due to potential hepatotoxicity, halothane was once a mainstay in anesthesia. | ||
* [[Desflurane]] | |||
* [[Halothane]] | |||
== Administration == | |||
Inhalational anesthetics are typically administered using an [[anesthesia machine]] equipped with a vaporizer. The vaporizer converts the liquid anesthetic into a vapor, which is then mixed with a carrier gas such as [[oxygen]] or [[nitrous oxide]]. The mixture is delivered to the patient through a [[face mask]] or [[endotracheal tube]]. | |||
=== | == Advantages and Disadvantages == | ||
=== Advantages === | |||
* | * '''Rapid Onset and Recovery''': Inhalational anesthetics allow for quick induction and emergence from anesthesia. | ||
* '''Easy Control''': The depth of anesthesia can be easily adjusted by changing the concentration of the anesthetic gas. | |||
=== Disadvantages === | |||
* '''Potential for Airway Irritation''': Some agents, like desflurane, can cause airway irritation and coughing. | |||
* '''Environmental Impact''': Inhalational anesthetics can contribute to [[greenhouse gas]] emissions. | |||
== | == Safety and Monitoring == | ||
Patients receiving inhalational anesthetics require careful monitoring of vital signs, including [[heart rate]], [[blood pressure]], and [[oxygen saturation]]. Anesthesia providers also monitor the concentration of anesthetic gases using a [[capnograph]] and gas analyzer to ensure patient safety. | |||
== | == Related Pages == | ||
* [[Anesthesia]] | |||
* [[ | * [[General anesthesia]] | ||
* | |||
* [[Anesthesia machine]] | * [[Anesthesia machine]] | ||
* [[ | * [[Vaporizer (anesthesia)]] | ||
[[Category:Anesthesia]] | |||
Latest revision as of 06:48, 16 February 2025
An overview of inhalational anesthetics used in medical practice
Inhalational Anesthetics[edit]

Inhalational anesthetics are a class of anesthetic agents that are administered through the respiratory system. These agents are primarily used to induce and maintain general anesthesia during surgical procedures. They are delivered via a vaporizer and inhaled by the patient, allowing for rapid onset and easy control of the depth of anesthesia.
Mechanism of Action[edit]
Inhalational anesthetics work by depressing the central nervous system, leading to a reversible loss of consciousness and sensation. The exact mechanism is not fully understood, but it is believed that these agents enhance the activity of inhibitory neurotransmitters such as gamma-aminobutyric acid (GABA) and inhibit excitatory neurotransmitters like glutamate. This results in decreased neuronal activity and altered synaptic transmission.
Common Inhalational Anesthetics[edit]
Several inhalational anesthetics are commonly used in clinical practice:
- Isoflurane: Known for its stability and minimal metabolism, isoflurane is widely used due to its favorable pharmacokinetic profile.
- Sevoflurane: Popular for its rapid induction and recovery times, sevoflurane is often used in outpatient procedures.
- Desflurane: Characterized by its low blood-gas solubility, desflurane allows for quick adjustments in anesthetic depth.
- Halothane: Although less commonly used today due to potential hepatotoxicity, halothane was once a mainstay in anesthesia.
Administration[edit]
Inhalational anesthetics are typically administered using an anesthesia machine equipped with a vaporizer. The vaporizer converts the liquid anesthetic into a vapor, which is then mixed with a carrier gas such as oxygen or nitrous oxide. The mixture is delivered to the patient through a face mask or endotracheal tube.
Advantages and Disadvantages[edit]
Advantages[edit]
- Rapid Onset and Recovery: Inhalational anesthetics allow for quick induction and emergence from anesthesia.
- Easy Control: The depth of anesthesia can be easily adjusted by changing the concentration of the anesthetic gas.
Disadvantages[edit]
- Potential for Airway Irritation: Some agents, like desflurane, can cause airway irritation and coughing.
- Environmental Impact: Inhalational anesthetics can contribute to greenhouse gas emissions.
Safety and Monitoring[edit]
Patients receiving inhalational anesthetics require careful monitoring of vital signs, including heart rate, blood pressure, and oxygen saturation. Anesthesia providers also monitor the concentration of anesthetic gases using a capnograph and gas analyzer to ensure patient safety.