Clotizolam: Difference between revisions
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== Clotizolam == | |||
[[File:Ro11-1465_structure.png|thumb|right|Chemical structure of Clotizolam]] | |||
'''Clotizolam''' is a [[thienotriazolodiazepine]] derivative, which is a class of [[benzodiazepine]] analogs. It is known for its [[anxiolytic]], [[sedative]], and [[hypnotic]] properties. Clotizolam is not widely used in clinical practice but has been studied for its potential therapeutic effects. | |||
Clotizolam is | |||
== | == Chemical Properties == | ||
== | Clotizolam is characterized by its unique chemical structure, which includes a thieno ring fused to a triazolodiazepine core. This structure is similar to other benzodiazepines but with distinct modifications that may influence its pharmacological activity. | ||
== Pharmacology == | |||
Clotizolam acts on the [[central nervous system]] by enhancing the effect of the neurotransmitter [[gamma-aminobutyric acid]] (GABA) at the [[GABA_A receptor]]. This action results in increased [[neuronal inhibition]], leading to its calming effects. The drug's pharmacokinetics, including its [[absorption]], [[distribution]], [[metabolism]], and [[excretion]], are similar to other benzodiazepines, although specific data on clotizolam may vary. | |||
== Clinical Use == | |||
While clotizolam is not commonly used in medical practice, it has been investigated for its potential use in treating [[anxiety disorders]], [[insomnia]], and other conditions where benzodiazepines are typically prescribed. Its use is limited due to the availability of other well-studied benzodiazepines with established safety profiles. | |||
== Side Effects == | |||
The side effects of clotizolam are similar to those of other benzodiazepines and may include [[drowsiness]], [[dizziness]], [[muscle weakness]], and [[cognitive impairment]]. Long-term use can lead to [[tolerance]], [[dependence]], and [[withdrawal symptoms]] upon discontinuation. | |||
== Legal Status == | |||
The legal status of clotizolam varies by country. In some regions, it may be classified as a controlled substance due to its potential for abuse and dependence. | |||
== Related Pages == | |||
* [[Benzodiazepine]] | * [[Benzodiazepine]] | ||
* [[ | * [[Anxiolytic]] | ||
* [[Sedative]] | |||
* [[Hypnotic]] | |||
* [[GABA_A receptor]] | * [[GABA_A receptor]] | ||
[[Category: | [[Category:Benzodiazepines]] | ||
[[Category: | [[Category:Sedatives]] | ||
[[Category:Hypnotics]] | [[Category:Hypnotics]] | ||
Latest revision as of 11:03, 15 February 2025
Clotizolam[edit]
Clotizolam is a thienotriazolodiazepine derivative, which is a class of benzodiazepine analogs. It is known for its anxiolytic, sedative, and hypnotic properties. Clotizolam is not widely used in clinical practice but has been studied for its potential therapeutic effects.
Chemical Properties[edit]
Clotizolam is characterized by its unique chemical structure, which includes a thieno ring fused to a triazolodiazepine core. This structure is similar to other benzodiazepines but with distinct modifications that may influence its pharmacological activity.
Pharmacology[edit]
Clotizolam acts on the central nervous system by enhancing the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA_A receptor. This action results in increased neuronal inhibition, leading to its calming effects. The drug's pharmacokinetics, including its absorption, distribution, metabolism, and excretion, are similar to other benzodiazepines, although specific data on clotizolam may vary.
Clinical Use[edit]
While clotizolam is not commonly used in medical practice, it has been investigated for its potential use in treating anxiety disorders, insomnia, and other conditions where benzodiazepines are typically prescribed. Its use is limited due to the availability of other well-studied benzodiazepines with established safety profiles.
Side Effects[edit]
The side effects of clotizolam are similar to those of other benzodiazepines and may include drowsiness, dizziness, muscle weakness, and cognitive impairment. Long-term use can lead to tolerance, dependence, and withdrawal symptoms upon discontinuation.
Legal Status[edit]
The legal status of clotizolam varies by country. In some regions, it may be classified as a controlled substance due to its potential for abuse and dependence.
