PRO-LAD: Difference between revisions

PRO-LAD
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Latest revision as of 10:50, 15 February 2025

A chemical compound related to LSD

PRO-LAD is a psychedelic compound that is structurally related to lysergic acid diethylamide (LSD). It belongs to the class of lysergamides, which are known for their potent effects on the serotonin receptors in the brain.

Chemical Structure[edit]

PRO-LAD is chemically known as (6aR,9R)-N,N-diethyl-7-propyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide. It is a derivative of the ergoline family, which is characterized by a tetracyclic ring structure. The presence of a propyl group at the 7-position differentiates it from other lysergamides such as LSD.

Pharmacology[edit]

PRO-LAD acts primarily as a partial agonist at the 5-HT2A receptor, which is believed to be responsible for its psychedelic effects. Like other lysergamides, it may also interact with other serotonin receptors, contributing to its complex pharmacological profile.

Effects[edit]

The effects of PRO-LAD are similar to those of LSD, including alterations in perception, mood, and cognition. Users may experience visual and auditory hallucinations, changes in thought patterns, and an altered sense of time. The intensity and duration of effects can vary depending on the dose and individual sensitivity.

Legal Status[edit]

The legal status of PRO-LAD varies by country. In some jurisdictions, it is classified as a controlled substance, while in others it may be unscheduled. Its legal status is often influenced by its structural similarity to LSD and other controlled lysergamides.

Related Compounds[edit]

PRO-LAD is part of a broader class of compounds known as lysergamides. Other related compounds include:

Related pages[edit]

@@ Line 1: / Line 1: @@
-'''PRO-LAD''' is a [[psychedelic drug]] related to [[LSD]]. It is described by Alexander Shulgin in the book [[TiHKAL]]. PRO-LAD is a member of the [[lysergamide]] family and it is quite uncommon relative to LSD, ALD-52, ETH-LAD, and other lysergamides.
+{{Short description|A chemical compound related to LSD}}
+{{Drugbox
+| verifiedrevid = 477318123
+| IUPAC_name = (6aR,9R)-N,N-diethyl-7-propyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
+| image = PRO-LAD_structure.png
+| image_size = 200px
+| image_alt = Chemical structure of PRO-LAD
+}}
-==Chemistry==
+'''PRO-LAD''' is a [[psychedelic]] compound that is structurally related to [[lysergic acid diethylamide]] (LSD). It belongs to the class of [[lysergamides]], which are known for their potent effects on the [[serotonin receptor|serotonin receptors]] in the brain.
-PRO-LAD, or 6-propyl-6-nor-lysergic acid diethylamide, is a synthetic alkaloid of the lysergamide class. It is structurally related to LSD and is named for the propyl group that is attached to the nitrogen of the polycyclic indole group of LSD.
+==Chemical Structure==
+[[File:PRO-LAD_structure.png|thumb|right|200px|Chemical structure of PRO-LAD]]
+PRO-LAD is chemically known as (6aR,9R)-N,N-diethyl-7-propyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide. It is a derivative of the [[ergoline]] family, which is characterized by a tetracyclic ring structure. The presence of a propyl group at the 7-position differentiates it from other lysergamides such as LSD.
 ==Pharmacology==
-Like LSD, PRO-LAD likely acts as a 5-HT2A partial agonist. The psychedelic effects are believed to come from PRO-LAD’s efficacy at the 5-HT2A receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.
+PRO-LAD acts primarily as a partial agonist at the [[5-HT2A receptor]], which is believed to be responsible for its psychedelic effects. Like other lysergamides, it may also interact with other [[serotonin receptor|serotonin receptors]], contributing to its complex pharmacological profile.
 ==Effects==
-The effects of PRO-LAD are reported to be somewhat similar to those of LSD, but with a shorter duration. The effects include:
+The effects of PRO-LAD are similar to those of LSD, including alterations in [[perception]], [[mood]], and [[cognition]]. Users may experience visual and auditory hallucinations, changes in thought patterns, and an altered sense of time. The intensity and duration of effects can vary depending on the dose and individual sensitivity.
-* Open and closed eye visuals
-* Euphoria
-* Time distortion
-* Increased introspection
-* Conceptual thinking
-* Synesthesia (perceiving senses as another, such as hearing colors, or seeing sounds)
-* Pupil dilation
-==Legality==
+==Legal Status==
-As of 2018, PRO-LAD is not controlled in the United States, but it could possibly be considered an analogue of LSD, which would make it illegal to buy, sell, or possess under the Federal Analogue Act.
+The legal status of PRO-LAD varies by country. In some jurisdictions, it is classified as a controlled substance, while in others it may be unscheduled. Its legal status is often influenced by its structural similarity to LSD and other controlled lysergamides.
-==See also==
+==Related Compounds==
+PRO-LAD is part of a broader class of compounds known as lysergamides. Other related compounds include:
+* [[LSD]]
 * [[AL-LAD]]
 * [[ETH-LAD]]
-* [[LSZ]]
 * [[1P-LSD]]
+==See Also==
 * [[Psychedelic drug]]
-* [[Lysergamide]]
+* [[Serotonin receptor]]
+* [[Lysergic acid diethylamide]]
-==References==
+==Related pages==
-<references />
+* [[Psychedelic research]]
+* [[History of lysergamides]]
 [[Category:Psychedelic drugs]]
 [[Category:Lysergamides]]
-[[Category:Designer drugs]]
-{{stub}}