Cefaloglycin: Difference between revisions

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'''Cefaloglycin''' is a first-generation [[cephalosporin]] antibiotic. It is a broad-spectrum antibiotic that is active against a wide range of [[bacteria]]. Cefaloglycin is derived from the fungus ''[[Cephalosporium]]'' and is chemically related to [[penicillin]].
{{Short description|An article about the antibiotic Cefaloglycin}}
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==Etymology==
'''Cefaloglycin''' is a [[cephalosporin]] [[antibiotic]] used in the treatment of various bacterial infections. It belongs to the first generation of cephalosporins and is known for its effectiveness against [[Gram-positive bacteria]].
The term "Cefaloglycin" is derived from the genus name of the fungus ''Cephalosporium'' from which it is obtained, and the suffix "-glycin" which is common in many antibiotics.


==Pharmacology==
==Chemical structure==
Cefaloglycin works by inhibiting the synthesis of the bacterial cell wall, leading to cell death. It is effective against both [[Gram-positive bacteria|Gram-positive]] and [[Gram-negative bacteria|Gram-negative]] bacteria. However, many bacteria have developed resistance to cefaloglycin, limiting its effectiveness.
[[File:Cefaloglycin.svg|thumb|right|Chemical structure of Cefaloglycin]]
Cefaloglycin is characterized by its beta-lactam ring, which is crucial for its antibacterial activity. The presence of the beta-lactam ring allows cefaloglycin to inhibit bacterial cell wall synthesis, leading to cell lysis and death.


==Clinical Use==
==Mechanism of action==
Cefaloglycin is used to treat a variety of bacterial infections, including [[respiratory tract infection|respiratory tract infections]], [[urinary tract infection|urinary tract infections]], [[skin infection|skin infections]], and [[bone infection|bone infections]]. It is also used in the prevention of bacterial infections in patients undergoing surgical procedures.
Cefaloglycin works by binding to [[penicillin-binding proteins]] (PBPs) located inside the bacterial cell wall. This binding inhibits the final transpeptidation step of [[peptidoglycan]] synthesis in bacterial cell walls, thus inhibiting cell wall biosynthesis. The inhibition of cell wall synthesis ultimately leads to bacterial cell death.


==Side Effects==
==Pharmacokinetics==
Like all antibiotics, cefaloglycin can cause side effects. The most common side effects include [[nausea]], [[vomiting]], [[diarrhea]], and [[allergic reaction|allergic reactions]]. In rare cases, cefaloglycin can cause serious side effects such as [[anaphylaxis]], a severe allergic reaction.
Cefaloglycin is administered orally and is absorbed from the gastrointestinal tract. It is distributed widely in body tissues and fluids. The drug is primarily excreted unchanged in the urine, making it effective for treating urinary tract infections.


==Related Terms==
==Clinical uses==
Cefaloglycin is used to treat a variety of infections caused by susceptible strains of bacteria. These include:
* [[Urinary tract infections]]
* [[Respiratory tract infections]]
* [[Skin and soft tissue infections]]
 
==Side effects==
Common side effects of cefaloglycin include gastrointestinal disturbances such as [[nausea]], [[vomiting]], and [[diarrhea]]. Allergic reactions, though rare, can occur and may manifest as [[rash]], [[pruritus]], or more severe reactions such as [[anaphylaxis]].
 
==Related pages==
* [[Cephalosporin]]
* [[Cephalosporin]]
* [[Antibiotic resistance]]
* [[Antibiotic]]
* [[Bacteria]]
* [[Beta-lactam antibiotic]]
* [[Penicillin]]
 
[[Category:Antibiotics]]
[[Category:Cephalosporins]]
[[Category:Pharmacology]]
[[Category:Medicine]]


{{stub}}
[[Category:Cephalosporin antibiotics]]
[[Category:Beta-lactam antibiotics]]

Latest revision as of 04:06, 13 February 2025

An article about the antibiotic Cefaloglycin


Cefaloglycin
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Cefaloglycin is a cephalosporin antibiotic used in the treatment of various bacterial infections. It belongs to the first generation of cephalosporins and is known for its effectiveness against Gram-positive bacteria.

Chemical structure[edit]

Chemical structure of Cefaloglycin

Cefaloglycin is characterized by its beta-lactam ring, which is crucial for its antibacterial activity. The presence of the beta-lactam ring allows cefaloglycin to inhibit bacterial cell wall synthesis, leading to cell lysis and death.

Mechanism of action[edit]

Cefaloglycin works by binding to penicillin-binding proteins (PBPs) located inside the bacterial cell wall. This binding inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls, thus inhibiting cell wall biosynthesis. The inhibition of cell wall synthesis ultimately leads to bacterial cell death.

Pharmacokinetics[edit]

Cefaloglycin is administered orally and is absorbed from the gastrointestinal tract. It is distributed widely in body tissues and fluids. The drug is primarily excreted unchanged in the urine, making it effective for treating urinary tract infections.

Clinical uses[edit]

Cefaloglycin is used to treat a variety of infections caused by susceptible strains of bacteria. These include:

Side effects[edit]

Common side effects of cefaloglycin include gastrointestinal disturbances such as nausea, vomiting, and diarrhea. Allergic reactions, though rare, can occur and may manifest as rash, pruritus, or more severe reactions such as anaphylaxis.

Related pages[edit]