Gepefrine: Difference between revisions
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{{Short description|Overview of the drug Gepefrine}} | |||
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'''Gepefrine''' is a [[sympathomimetic drug]] that is used primarily for its [[vasoconstrictor]] and [[bronchodilator]] effects. It is a synthetic compound that mimics the effects of endogenous [[catecholamines]] such as [[epinephrine]] and [[norepinephrine]]. | |||
Gepefrine is a [[ | |||
==Pharmacology== | ==Pharmacology== | ||
Gepefrine acts | Gepefrine acts on the [[adrenergic receptors]] in the body, particularly the [[alpha-adrenergic receptor|alpha]] and [[beta-adrenergic receptor|beta]] receptors. By stimulating these receptors, Gepefrine induces [[vasoconstriction]], which leads to an increase in [[blood pressure]]. It also causes [[bronchodilation]], making it useful in the treatment of conditions such as [[asthma]] and [[chronic obstructive pulmonary disease]] (COPD). | ||
== | ==Mechanism of Action== | ||
Gepefrine is used in the | Gepefrine works by binding to adrenergic receptors on the surface of cells. This binding activates the [[G protein-coupled receptor]] pathways, leading to an increase in intracellular [[cyclic adenosine monophosphate]] (cAMP) levels. The rise in cAMP results in the relaxation of smooth muscle cells in the [[bronchi]] and the contraction of smooth muscle cells in the [[blood vessels]]. | ||
==Clinical Uses== | |||
Gepefrine is used in the management of several medical conditions: | |||
* As a [[bronchodilator]] in the treatment of [[asthma]] and [[COPD]]. | |||
* As a [[vasopressor]] agent in the management of [[hypotension]] during [[anesthesia]] or [[shock]]. | |||
==Side Effects== | ==Side Effects== | ||
Common side effects of Gepefrine include: | |||
* [[Tachycardia]] | |||
* [[Hypertension]] | |||
* [[Anxiety]] | |||
* [[Tremors]] | |||
==Administration== | |||
Gepefrine is typically administered via [[intravenous]] or [[intramuscular]] injection. The dosage and route of administration depend on the clinical condition being treated and the patient's response to the drug. | |||
== | ==Related pages== | ||
* [[Sympathomimetic drug]] | * [[Sympathomimetic drug]] | ||
* [[ | * [[Adrenergic receptor]] | ||
* [[ | * [[Bronchodilator]] | ||
* [[Vasoconstrictor]] | |||
[[Category: | [[Category:Sympathomimetic amines]] | ||
[[Category: | [[Category:Bronchodilators]] | ||
[[Category:Vasoconstrictors]] | [[Category:Vasoconstrictors]] | ||
Revision as of 04:05, 13 February 2025
Overview of the drug Gepefrine
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Gepefrine is a sympathomimetic drug that is used primarily for its vasoconstrictor and bronchodilator effects. It is a synthetic compound that mimics the effects of endogenous catecholamines such as epinephrine and norepinephrine.
Pharmacology
Gepefrine acts on the adrenergic receptors in the body, particularly the alpha and beta receptors. By stimulating these receptors, Gepefrine induces vasoconstriction, which leads to an increase in blood pressure. It also causes bronchodilation, making it useful in the treatment of conditions such as asthma and chronic obstructive pulmonary disease (COPD).
Mechanism of Action
Gepefrine works by binding to adrenergic receptors on the surface of cells. This binding activates the G protein-coupled receptor pathways, leading to an increase in intracellular cyclic adenosine monophosphate (cAMP) levels. The rise in cAMP results in the relaxation of smooth muscle cells in the bronchi and the contraction of smooth muscle cells in the blood vessels.
Clinical Uses
Gepefrine is used in the management of several medical conditions:
- As a bronchodilator in the treatment of asthma and COPD.
- As a vasopressor agent in the management of hypotension during anesthesia or shock.
Side Effects
Common side effects of Gepefrine include:
Administration
Gepefrine is typically administered via intravenous or intramuscular injection. The dosage and route of administration depend on the clinical condition being treated and the patient's response to the drug.
