Guanosine: Difference between revisions
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== | ==Guanosine== | ||
Guanosine | [[File:GuanosinN.svg|thumb|right|Chemical structure of guanosine]] | ||
'''Guanosine''' is a [[nucleoside]] comprising the [[nucleobase]] [[guanine]] attached to a [[ribose]] (ribofuranose) ring via a _-N9-glycosidic bond. It is one of the four main nucleosides found in [[ribonucleic acid]] (RNA), the others being [[adenosine]], [[cytidine]], and [[uridine]]. | |||
== | ==Structure and Properties== | ||
Guanosine | Guanosine consists of a guanine base linked to a ribose sugar. The chemical formula of guanosine is C<sub>10</sub>H<sub>13</sub>N<sub>5</sub>O<sub>5</sub>. The structure of guanosine allows it to participate in hydrogen bonding, which is crucial for the formation of the [[double helix]] structure of [[nucleic acids]]. | ||
== | ==Biological Role== | ||
In the context of [[RNA]], guanosine plays a critical role in the encoding of genetic information. It pairs with [[cytosine]] through three hydrogen bonds, contributing to the stability of the RNA structure. Guanosine is also involved in various cellular processes, including [[signal transduction]] and [[metabolism]]. | |||
=== | ==Metabolism== | ||
Guanosine is metabolized in the body to produce [[guanosine monophosphate]] (GMP), which is a precursor to [[guanosine triphosphate]] (GTP). GTP is an essential molecule in [[cellular energy transfer]], [[protein synthesis]], and [[signal transduction]]. | |||
== | ==Synthesis== | ||
Guanosine can be synthesized in the laboratory through the chemical reaction of guanine with ribose. In biological systems, it is synthesized from [[inosine monophosphate]] (IMP) through a series of enzymatic reactions. | |||
== | ==Applications== | ||
Guanosine and its derivatives are used in various research and clinical applications. They are important in the study of [[nucleic acid]] interactions and are used in the development of [[antiviral]] and [[anticancer]] drugs. | |||
== | ==Related Pages== | ||
* [[Nucleoside]] | * [[Nucleoside]] | ||
* [[Nucleotide]] | * [[Nucleotide]] | ||
* [[ | * [[RNA]] | ||
* [[Guanine]] | * [[Guanine]] | ||
* [[ | * [[Cytosine]] | ||
[[Category:Nucleosides]] | [[Category:Nucleosides]] | ||
Latest revision as of 03:58, 13 February 2025
Guanosine[edit]
Guanosine is a nucleoside comprising the nucleobase guanine attached to a ribose (ribofuranose) ring via a _-N9-glycosidic bond. It is one of the four main nucleosides found in ribonucleic acid (RNA), the others being adenosine, cytidine, and uridine.
Structure and Properties[edit]
Guanosine consists of a guanine base linked to a ribose sugar. The chemical formula of guanosine is C10H13N5O5. The structure of guanosine allows it to participate in hydrogen bonding, which is crucial for the formation of the double helix structure of nucleic acids.
Biological Role[edit]
In the context of RNA, guanosine plays a critical role in the encoding of genetic information. It pairs with cytosine through three hydrogen bonds, contributing to the stability of the RNA structure. Guanosine is also involved in various cellular processes, including signal transduction and metabolism.
Metabolism[edit]
Guanosine is metabolized in the body to produce guanosine monophosphate (GMP), which is a precursor to guanosine triphosphate (GTP). GTP is an essential molecule in cellular energy transfer, protein synthesis, and signal transduction.
Synthesis[edit]
Guanosine can be synthesized in the laboratory through the chemical reaction of guanine with ribose. In biological systems, it is synthesized from inosine monophosphate (IMP) through a series of enzymatic reactions.
Applications[edit]
Guanosine and its derivatives are used in various research and clinical applications. They are important in the study of nucleic acid interactions and are used in the development of antiviral and anticancer drugs.
