Prosorba column

Prosorba Column

The Prosorba Column is a medical device used for the treatment of rheumatoid arthritis. It is a type of immunoadsorption therapy that removes certain antibodies from the blood.

Overview

The Prosorba Column is a device that is filled with a material known as protein A. Protein A has the ability to bind to certain types of antibodies, specifically IgG antibodies. These antibodies are often found in high levels in people with rheumatoid arthritis and are believed to contribute to the disease.

The patient's blood is passed through the Prosorba Column, where the protein A binds to the IgG antibodies. The blood is then returned to the patient, minus the antibodies. This process is known as leukapheresis.

Use in Treatment

The Prosorba Column is used in the treatment of severe rheumatoid arthritis in patients who have not responded to other treatments. It is typically used in combination with other therapies, such as methotrexate.

The treatment involves weekly sessions over a period of 12 weeks. Each session lasts approximately 2-3 hours.

Side Effects

Like all medical treatments, the use of the Prosorba Column can have side effects. These can include fever, chills, nausea, and low blood pressure. In rare cases, serious side effects such as anaphylaxis can occur.

See Also

• Rheumatoid arthritis
• Immunoadsorption
• Leukapheresis
• Protein A
• IgG

References

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