Triamcinolone diacetate: Difference between revisions

Triamcinolone diacetate
INN
Drug class
Routes of administration
Pregnancy category
Bioavailability
Metabolism
Elimination half-life
Excretion
Legal status
CAS Number	3870-07-3
PubChem	5281060
DrugBank
ChemSpider	4447590
KEGG

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Revision as of 15:45, 9 February 2025

A synthetic corticosteroid used in various medical treatments

Triamcinolone diacetate is a synthetic corticosteroid used in the treatment of various inflammatory and autoimmune conditions. It is a derivative of triamcinolone, modified to enhance its pharmacological properties.

Pharmacology

Triamcinolone diacetate functions by mimicking the effects of cortisol, a naturally occurring hormone produced by the adrenal glands. It exerts its effects by binding to glucocorticoid receptors, leading to a decrease in the production of inflammatory mediators and suppression of the immune response.

Medical uses

Triamcinolone diacetate is used in the management of conditions such as allergic reactions, asthma, rheumatoid arthritis, and dermatological disorders. It is often administered via injection to provide localized anti-inflammatory effects.

Side effects

Common side effects of triamcinolone diacetate include skin thinning, bruising, and hyperglycemia. Long-term use can lead to more serious effects such as osteoporosis, adrenal suppression, and Cushing's syndrome.

Mechanism of action

The drug works by inhibiting the release of substances in the body that cause inflammation. It reduces the activity of the immune system by interfering with the function of white blood cells and other components of the immune response.

Related pages

References

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-'''Triamcinolone diacetate''' is a type of [[corticosteroid]] used in the treatment of various [[medical conditions]]. It is a synthetic steroid that has anti-inflammatory and immunosuppressive properties.
+{{Short description|A synthetic corticosteroid used in various medical treatments}}
+{{Drugbox
+| verifiedfields = changed
+| verifiedrevid = 477241123
+| image = Triamcinolone_diacetate.svg
+| width = 200px
+| image2 =
+| width2 =
+| tradename =
+| Drugs.com =
+| pregnancy_AU =
+| pregnancy_US =
+| legal_AU =
+| legal_CA =
+| legal_UK =
+| legal_US =
+| routes_of_administration =
+| bioavailability =
+| protein_bound =
+| metabolism =
+| elimination_half-life =
+| excretion =
+| CAS_number = 3870-07-3
+| ATC_prefix =
+| ATC_suffix =
+| PubChem = 5281060
+| DrugBank =
+| ChemSpiderID = 4447590
+| UNII = 0VZ1QQV63Y
+| KEGG =
+| ChEBI = 32232
+| ChEMBL = 1200480
+| synonyms =
+}}
+'''Triamcinolone diacetate''' is a synthetic [[corticosteroid]] used in the treatment of various inflammatory and autoimmune conditions. It is a derivative of [[triamcinolone]], modified to enhance its pharmacological properties.
 ==Pharmacology==
-Triamcinolone diacetate works by decreasing the body's immune response to reduce symptoms such as swelling and allergic-type reactions. It is a derivative of [[prednisone]], and its potency is about eight times that of prednisone.
+Triamcinolone diacetate functions by mimicking the effects of [[cortisol]], a naturally occurring hormone produced by the [[adrenal glands]]. It exerts its effects by binding to [[glucocorticoid receptors]], leading to a decrease in the production of inflammatory mediators and suppression of the immune response.
-==Uses==
+==Medical uses==
-Triamcinolone diacetate is used to treat a variety of conditions, including [[rheumatoid arthritis]], [[psoriasis]], [[eczema]], and [[allergic reactions]]. It is also used in the treatment of certain eye diseases and for the management of acute [[gout]] attacks.
+Triamcinolone diacetate is used in the management of conditions such as [[allergic reactions]], [[asthma]], [[rheumatoid arthritis]], and [[dermatological disorders]]. It is often administered via injection to provide localized anti-inflammatory effects.
-==Side Effects==
+==Side effects==
-Like all medications, triamcinolone diacetate can cause side effects. These may include weight gain, mood changes, and increased blood sugar levels. Long-term use can lead to more serious side effects such as osteoporosis, cataracts, and an increased risk of infection.
+Common side effects of triamcinolone diacetate include [[skin thinning]], [[bruising]], and [[hyperglycemia]]. Long-term use can lead to more serious effects such as [[osteoporosis]], [[adrenal suppression]], and [[Cushing's syndrome]].
-==Precautions==
+==Mechanism of action==
-Patients using triamcinolone diacetate should be monitored for changes in blood sugar levels and signs of infection. It should be used with caution in patients with diabetes or those with a history of [[tuberculosis]].
+The drug works by inhibiting the release of substances in the body that cause inflammation. It reduces the activity of the immune system by interfering with the function of [[white blood cells]] and other components of the immune response.
-==See Also==
+==Related pages==
 * [[Corticosteroid]]
-* [[Prednisone]]
+* [[Triamcinolone]]
-* [[Rheumatoid arthritis]]
+* [[Glucocorticoid]]
-* [[Psoriasis]]
-* [[Eczema]]
+==References==
-* [[Allergic reactions]]
+{{Reflist}}
-* [[Gout]]
-* [[Tuberculosis]]
-[[Category:Pharmacology]]
+[[Category:Corticosteroids]]
-[[Category:Medicine]]
+[[Category:Anti-inflammatory agents]]
-[[Category:Drugs]]
-{{Pharma-stub}}
-{{Medicine-stub}}