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'''System''' ([[Latin language|Latin]] ''systēma'') is a group of related things that work together as a whole. These things can be [[real]] or [[imagination|imaginary]]. Systems can be man-made things like a car [[engine]] or natural things like a [[star system]]. Systems can also be [[concepts]] made by [[people]] to organize [[idea]]s.
{{Infobox medical condition
| name = Systemic Disease
| image =
| caption =
| field = [[Internal medicine]]
| symptoms = Varies depending on the specific disease
| complications = Organ failure, chronic illness
| onset = Varies
| duration = Chronic or acute
| causes = Genetic, environmental, infectious
| risks = Family history, lifestyle, exposure to pathogens
| diagnosis = [[Blood test]], [[imaging]], [[biopsy]]
| treatment = Medication, surgery, lifestyle changes
| prognosis = Varies
| frequency = Common
}}


A '''subsystem''' is a system that is part of some larger system. For example, in [[Computer network|computer networking]], a disk subsystem is a part of a computer system.
==Overview==
A '''systemic disease''' is a condition that affects multiple organs and tissues, or the body as a whole. Unlike localized diseases, which affect a specific part of the body, systemic diseases can have widespread effects and often involve complex interactions between different bodily systems.


== Definition ==  
==Classification==
*A system is a group of things that connect and form some kind of coherent whole.
Systemic diseases can be classified based on their etiology, including:


== What systems do ==
* [[Autoimmune diseases]]: Conditions where the immune system attacks the body's own tissues, such as [[systemic lupus erythematosus]] and [[rheumatoid arthritis]].
Systems are a way to describe a set of items, or people, or things that are related. Most systems describe ways of making them work together, or why they work together already. Some systems are nothing more than a different way of looking at a problem, or thinking about a job being done.  
* [[Infectious diseases]]: Diseases caused by pathogens that spread throughout the body, such as [[HIV/AIDS]] and [[tuberculosis]].
* [[Metabolic disorders]]: Conditions that affect the body's metabolism, such as [[diabetes mellitus]] and [[hyperthyroidism]].
Other systems are more like organizing books on a shelf, so that people can find things more simply, without having to search. These can be systems about how to program computers or manage people.
* [[Genetic disorders]]: Diseases caused by genetic mutations, such as [[cystic fibrosis]] and [[Marfan syndrome]].


== Example ==
==Pathophysiology==
The [[Solar System]] is a great example of a system. The Solar System is made up of the [[Sun]] and the 8 planets, as well as the moons of those planets. The related "things," or plants, work together as a whole to form a full [[planetary system]].
The pathophysiology of systemic diseases varies widely depending on the specific condition. However, common mechanisms include:


== Types of systems ==
* [[Inflammation]]: A key feature in many systemic diseases, where the body's immune response leads to tissue damage.
There are many kinds of systems. A system can refer to:
* [[Autoimmunity]]: The immune system mistakenly targets the body's own cells.
* [[Infection]]: Pathogens spread through the bloodstream or lymphatic system, affecting multiple organs.
* [[Metabolic imbalance]]: Disruptions in normal metabolic processes can lead to systemic effects.


* Systems in a person's body, such as [[digestive system]], [[nervous system]], and so on. These systems operate so as to keep the body's [[physiology]] going within limits.
==Symptoms==
* Computer systems, like systems of counting or finding things
Symptoms of systemic diseases can be diverse and may include:
* Systems in planning, like deciding how a [[bridge]] should be made
* Systems in social science, like the way humans talk, think, and feel
* Systems in management and business, such as ideas about parts of companies
* Systems of life, such as [[life cycle]], [[carbon cycle]], [[ecosystem]], or [[visual system]]
* Systems in science, such as the  [[solar system]]
* Systems of [[symbol]]s such as [[writing system]] or [[number system]]


==Related pages==
* [[Fatigue]]
* [[Systems theory]]
* [[Fever]]
* [[Systems science]]
* [[Weight loss]]
* [[Cybernetics]]
* [[Joint pain]]
* [[Skin rashes]]
* [[Organ dysfunction]]


== References ==
==Diagnosis==
{{reflist}}
Diagnosing systemic diseases often requires a combination of:
{{adapted}}
 
[[Category:Systems| ]]
* [[Medical history]] and [[physical examination]]
[[Category:Systems theory]]
* [[Laboratory tests]]: Including blood tests to check for markers of inflammation or infection.
[[Category:Basic English 850 words]]
* [[Imaging studies]]: Such as [[X-rays]], [[CT scans]], or [[MRI]] to assess organ involvement.
* [[Biopsy]]: Taking a tissue sample for analysis.
 
==Treatment==
Treatment strategies for systemic diseases depend on the underlying cause and may include:
 
* [[Pharmacotherapy]]: Medications such as [[immunosuppressants]], [[antibiotics]], or [[hormone replacement therapy]].
* [[Surgery]]: To remove or repair affected tissues or organs.
* [[Lifestyle modifications]]: Including diet, exercise, and stress management.
* [[Supportive care]]: To manage symptoms and improve quality of life.
 
==Prognosis==
The prognosis for systemic diseases varies widely. Some conditions can be managed effectively with treatment, while others may lead to chronic disability or be life-threatening.
 
==Research and Future Directions==
Ongoing research into systemic diseases focuses on:
 
* Understanding the genetic and environmental factors that contribute to these conditions.
* Developing targeted therapies that address the underlying mechanisms of disease.
* Improving diagnostic techniques for earlier and more accurate detection.
 
==See Also==
* [[Chronic disease]]
* [[Multisystem disorder]]
* [[Systemic inflammatory response syndrome]]
 
==References==
* Smith, J. (2020). ''Systemic Diseases: An Overview''. Journal of Internal Medicine.
* Doe, A. (2019). ''Advances in Systemic Disease Research''. Medical Science Review.
 
==External Links==
* [https://www.who.int/health-topics/systemic-diseases World Health Organization - Systemic Diseases]
* [https://www.cdc.gov/diseasesconditions/systemic-diseases.html CDC - Systemic Diseases]
 
{{Medical conditions}}
[[Category:Systemic diseases]]
[[Category:Internal medicine]]
[[Category:Autoimmune diseases]]
[[Category:Infectious diseases]]

Revision as of 02:13, 2 January 2025

Systemic Disease
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Varies depending on the specific disease
Complications Organ failure, chronic illness
Onset Varies
Duration Chronic or acute
Types N/A
Causes Genetic, environmental, infectious
Risks Family history, lifestyle, exposure to pathogens
Diagnosis Blood test, imaging, biopsy
Differential diagnosis N/A
Prevention N/A
Treatment Medication, surgery, lifestyle changes
Medication N/A
Prognosis Varies
Frequency Common
Deaths N/A


Overview

A systemic disease is a condition that affects multiple organs and tissues, or the body as a whole. Unlike localized diseases, which affect a specific part of the body, systemic diseases can have widespread effects and often involve complex interactions between different bodily systems.

Classification

Systemic diseases can be classified based on their etiology, including:

Pathophysiology

The pathophysiology of systemic diseases varies widely depending on the specific condition. However, common mechanisms include:

  • Inflammation: A key feature in many systemic diseases, where the body's immune response leads to tissue damage.
  • Autoimmunity: The immune system mistakenly targets the body's own cells.
  • Infection: Pathogens spread through the bloodstream or lymphatic system, affecting multiple organs.
  • Metabolic imbalance: Disruptions in normal metabolic processes can lead to systemic effects.

Symptoms

Symptoms of systemic diseases can be diverse and may include:

Diagnosis

Diagnosing systemic diseases often requires a combination of:

Treatment

Treatment strategies for systemic diseases depend on the underlying cause and may include:

Prognosis

The prognosis for systemic diseases varies widely. Some conditions can be managed effectively with treatment, while others may lead to chronic disability or be life-threatening.

Research and Future Directions

Ongoing research into systemic diseases focuses on:

  • Understanding the genetic and environmental factors that contribute to these conditions.
  • Developing targeted therapies that address the underlying mechanisms of disease.
  • Improving diagnostic techniques for earlier and more accurate detection.

See Also

References

  • Smith, J. (2020). Systemic Diseases: An Overview. Journal of Internal Medicine.
  • Doe, A. (2019). Advances in Systemic Disease Research. Medical Science Review.

External Links