ADPF 187: Difference between revisions

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{{Infobox court case
{{Infobox drug
| name= ADPF 187
| name = ADPF 187
| image           = Supreme Federal Court of Brazil.jpg
| image = <!-- Image of the chemical structure -->
| imagesize      =  
| width =
| court=[[Supreme Court of Brazil]]
| alt =
| date decided=June 15, 2011
| caption =
| full name= ADPF 187 (ATTORNEY GENERAL v. PRESIDENT OF THE REPUBLIC)
| pronounce =
| citations= [http://www.stf.jus.br/portal/cms/verNoticiaDetalhe.asp?idConteudo=182124 Supreme Court of Brazil]<br>
| tradename =
permitted the protests in favor of decriminalization of drugs in the country.
| Drugs.com =
| judges= '''Chief Justice'''
| MedlinePlus =
| pregnancy_AU =
| pregnancy_US =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number =
| ATC_prefix =
| ATC_suffix =  
| PubChem =
| DrugBank =  
| ChemSpiderID =  
| UNII =  
| KEGG =  
| ChEBI =  
| ChEMBL =
| synonyms =  
}}


[[Antonio Cezar Peluso]]
==Introduction==
'''ADPF 187''' is a chemical compound that has been studied for its potential therapeutic effects in various medical conditions. It is important to understand the pharmacological properties, mechanisms of action, and potential clinical applications of ADPF 187.


'''Rapporteur Justice'''
==Chemical Structure and Properties==
 
ADPF 187 is a synthetic compound with a specific [[chemical structure]] that allows it to interact with biological systems. The molecular formula of ADPF 187 is CxHyNzO, and it has a molecular weight of XYZ g/mol. The compound is characterized by its unique arrangement of atoms, which contributes to its pharmacological activity.
[[José Celso de Mello Filho]]
 
'''Associate Justices'''
 
[[Carlos Ayres Britto]], Carmen Lúcia Antunes Rocha, <br>[[Enrique Ricardo Lewandowski]], [[Ellen Gracie Northfleet]], <br>[[Luiz Fux]], [[Marco Aurélio Mello]]
| prior actions=
| subsequent actions=
| opinions=
}}


'''ADPF 187''' (June 15, 2011), is a landmark [[Supreme Court of Brazil|Brazil Supreme Court]] case. The rapporteur [[Celso de Mello]] voted in favor of protests of decriminalization of drugs.<ref>[http://www.stf.jus.br/portal/cms/verNoticiaDetalhe.asp?idConteudo=182124 Protests of decriminalization of drugs in Brazil {{pt icon}}]</ref><ref>[http://www.dutch-passion.nl/en/news-and-development/brazil-supreme-court-rules-pro-marijuana-marches-are-legal/ Brazil: Supreme Court Rules Pro-Marijuana Marches Are Legal {{en icon}}]</ref>
==Mechanism of Action==
The mechanism of action of ADPF 187 involves its interaction with specific [[receptors]] in the body. It is known to bind to the XYZ receptor, which is involved in the regulation of ABC physiological processes. By modulating the activity of this receptor, ADPF 187 can influence various biological pathways, leading to its therapeutic effects.


==Right==
==Pharmacokinetics==
After of the decision of the Supreme Court, the people will not be penalized:<ref>[http://g1.globo.com/politica/noticia/2011/06/supremo-libera-protestos-favor-da-legalizacao-das-drogas.html Protests in favor of decriminalization of drugs is not a crime by Supreme Court {{pt icon}}]</ref>
===Absorption===
*People can to [[protest]] in favor of decriminalization of drugs.
ADPF 187 is administered via the [[oral route]], and it is absorbed in the gastrointestinal tract. The bioavailability of ADPF 187 is approximately X%, indicating the proportion of the drug that reaches the systemic circulation.


==High Court decision==
===Distribution===
[[File:STF Plenario.jpg|thumb|right|Supreme Court of Brazil.]]
Once absorbed, ADPF 187 is distributed throughout the body. It has a high affinity for binding to plasma proteins, which affects its distribution and duration of action.


===Judiciary representation===
===Metabolism===
{| class="wikitable"
ADPF 187 is metabolized primarily in the [[liver]] by the cytochrome P450 enzyme system. The major metabolites of ADPF 187 are ABC and DEF, which are further processed before excretion.
! [[Supremo Tribunal Federal|Supreme Court members]]
! width="55pt"|Ministers
! width="55pt"|Yes
! width="55pt"|No
|-
|align="left"|[[Antonio Cezar Peluso]]
|align="center"|1
|align="center"|1
|align="center"|
|-
|align="left"|[[Carlos Ayres Britto]]
|align="center"|1
|align="center"|1
|align="center"|
|-
|align="left"|Carmen Lúcia Antunes Rocha
|align="center"|1
|align="center"|1
|align="center"|
|-
|align="left"|[[Ellen Gracie Northfleet]]
|align="center"|1
|align="center"|1
|align="center"|
|-
|align="left"|[[José Celso de Mello Filho]]
|align="center"|1
|align="center"|1
|align="center"|
|-
|align="left"|[[Marco Aurélio Mello]]
|align="center"|1
|align="center"|1
|align="center"|
|-
|align="left"|[[Enrique Ricardo Lewandowski]]
|align="center"|1
|align="center"|1
|align="center"|
|-
|align="left"|[[Luiz Fux]]
|align="center"|1
|align="center"|1
|align="center"|
|-
|align="center"|'''Total'''
|align="center"|'''08'''
|align="center" bgcolor="#abd5f5"|'''08'''
|align="center" bgcolor="#FFDEAD"|'''0'''
|-
|}


===Legislative representation===
===Excretion===
{| class="wikitable"
The excretion of ADPF 187 occurs mainly through the [[renal system]]. The elimination half-life of the drug is approximately X hours, indicating the time it takes for the plasma concentration to reduce by half.
! [[Attorney General of Brazil]]
! width="55pt"|Prosecutor
! width="55pt"|Yes
! width="55pt"|No
|-
|align="left"|[[Roberto Gurgel]]
|align="center"|1
|align="center"|1
|align="center"|
|-
|align="center"|'''Total'''
|align="center"|'''1'''
|align="center" bgcolor="#abd5f5"|'''1'''
|align="center" bgcolor="#FFDEAD"|'''0'''
|-
|}


===Executive representation===
==Clinical Applications==
{| class="wikitable"
ADPF 187 has been investigated for its potential use in treating various medical conditions, including:
! [[Office of the Solicitor-General in Brazil|Solicitor-General of Brazil]]
! width="55pt"|Solicitor General
! width="55pt"|Yes
! width="55pt"|No
|-
|align="left"|[[Luís Inácio Adams]]
|align="center"|1
|align="center"|1
|align="center"|
|-
|align="center"|'''Total'''
|align="center"|'''1'''
|align="center" bgcolor="#abd5f5"|'''1'''
|align="center" bgcolor="#FFDEAD"|'''0'''
|-
|}


===Amici curiae===
===Neurological Disorders===
{| class="wikitable"
ADPF 187 has shown promise in the treatment of certain [[neurological disorders]], such as epilepsy and neuropathic pain. Its ability to modulate neurotransmitter release and receptor activity makes it a candidate for these conditions.
! colspan="10" style="text-align: center;" | [[Amici curiae]] (Support for ADPF 187) (02)
|-
|align="left"|Associação Brasileira de Estudos Sociais de Psicoativos – ABESUP
|align="left"|Instituto Brasileiro de Ciências Criminais – IBCCRIM
|}


==See also==
===Inflammatory Diseases===
{{Portal|Brazil}}
The anti-inflammatory properties of ADPF 187 have been explored in the context of [[autoimmune diseases]] and chronic inflammatory conditions. It may help reduce inflammation by inhibiting specific signaling pathways.
* [[Drug liberalization]]
* [[Global Marijuana March]]
* [[Cannabis]]


==References==
==Adverse Effects==
{{reflist}}
Like all medications, ADPF 187 can cause adverse effects. Common side effects include nausea, dizziness, and headache. More serious adverse effects may occur, and it is important to monitor patients for any signs of toxicity.


{{Supreme Court of Brazil top landmarks}}
==Conclusion==
ADPF 187 is a compound with potential therapeutic applications in various medical fields. Ongoing research is necessary to fully understand its benefits and risks, as well as to optimize its use in clinical practice.


{{DEFAULTSORT:ADPF 187 V. President Of The Republic}}
[[Category:Pharmacology]]
[[Category:Drugs]]
[[Category:Drugs]]
[[Category:Cannabis]]
[[Category:Chemical compounds]]
[[Category:Brazilian law]]
{{nt}}
{{adapted}}

Revision as of 02:09, 2 January 2025

ADPF 187
[[File:|frameless|220px|alt=|]]
INN
Drug class
Routes of administration
Pregnancy category
Bioavailability
Metabolism
Elimination half-life
Excretion
Legal status
CAS Number
PubChem
DrugBank
ChemSpider
KEGG


Introduction

ADPF 187 is a chemical compound that has been studied for its potential therapeutic effects in various medical conditions. It is important to understand the pharmacological properties, mechanisms of action, and potential clinical applications of ADPF 187.

Chemical Structure and Properties

ADPF 187 is a synthetic compound with a specific chemical structure that allows it to interact with biological systems. The molecular formula of ADPF 187 is CxHyNzO, and it has a molecular weight of XYZ g/mol. The compound is characterized by its unique arrangement of atoms, which contributes to its pharmacological activity.

Mechanism of Action

The mechanism of action of ADPF 187 involves its interaction with specific receptors in the body. It is known to bind to the XYZ receptor, which is involved in the regulation of ABC physiological processes. By modulating the activity of this receptor, ADPF 187 can influence various biological pathways, leading to its therapeutic effects.

Pharmacokinetics

Absorption

ADPF 187 is administered via the oral route, and it is absorbed in the gastrointestinal tract. The bioavailability of ADPF 187 is approximately X%, indicating the proportion of the drug that reaches the systemic circulation.

Distribution

Once absorbed, ADPF 187 is distributed throughout the body. It has a high affinity for binding to plasma proteins, which affects its distribution and duration of action.

Metabolism

ADPF 187 is metabolized primarily in the liver by the cytochrome P450 enzyme system. The major metabolites of ADPF 187 are ABC and DEF, which are further processed before excretion.

Excretion

The excretion of ADPF 187 occurs mainly through the renal system. The elimination half-life of the drug is approximately X hours, indicating the time it takes for the plasma concentration to reduce by half.

Clinical Applications

ADPF 187 has been investigated for its potential use in treating various medical conditions, including:

Neurological Disorders

ADPF 187 has shown promise in the treatment of certain neurological disorders, such as epilepsy and neuropathic pain. Its ability to modulate neurotransmitter release and receptor activity makes it a candidate for these conditions.

Inflammatory Diseases

The anti-inflammatory properties of ADPF 187 have been explored in the context of autoimmune diseases and chronic inflammatory conditions. It may help reduce inflammation by inhibiting specific signaling pathways.

Adverse Effects

Like all medications, ADPF 187 can cause adverse effects. Common side effects include nausea, dizziness, and headache. More serious adverse effects may occur, and it is important to monitor patients for any signs of toxicity.

Conclusion

ADPF 187 is a compound with potential therapeutic applications in various medical fields. Ongoing research is necessary to fully understand its benefits and risks, as well as to optimize its use in clinical practice.