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== EC-Hippocampus System ==


The '''EC-Hippocampus System''' is a complex neural network that plays a crucial role in memory formation and spatial navigation. It consists of two primary components: the [[Entorhinal Cortex]] (EC) and the [[Hippocampus]].
{{Infobox brain
| Name = EC-hippocampus system
| Image =
| Caption =
| Latin =
| Width =
| IsPartOf = [[Limbic system]]
| Components = [[Entorhinal cortex]], [[Hippocampus]]
| Artery =
| Vein =
| System = [[Nervous system]]
}}


[[File:Gray727 entorhinal cortex.png|thumb|right|250px|The Entorhinal Cortex (EC) is a crucial component of the EC-Hippocampus System.]]
The '''EC-hippocampus system''' is a critical component of the [[brain]] involved in [[memory]] and [[navigation]]. It primarily consists of the [[entorhinal cortex]] (EC) and the [[hippocampus]].


=== Entorhinal Cortex ===
==Structure==
The EC-hippocampus system is part of the [[limbic system]], which is involved in [[emotion]] and [[memory]]. The [[entorhinal cortex]] serves as a major input and output structure for the [[hippocampus]], facilitating the flow of information between the [[neocortex]] and the [[hippocampus]].


The [[Entorhinal Cortex]] (EC) is located in the medial temporal lobe and serves as the main interface between the hippocampus and neocortex. It is involved in a variety of cognitive processes, including memory and navigation. The EC is divided into two main regions: the medial entorhinal cortex (MEC) and the lateral entorhinal cortex (LEC), each of which has distinct functions and connectivity patterns.
===Entorhinal Cortex===
The [[entorhinal cortex]] is located in the [[medial temporal lobe]] and is a crucial hub in the [[brain]]'s [[memory]] network. It is involved in the processing of [[spatial memory]] and [[navigation]].


=== Hippocampus ===
===Hippocampus===
The [[hippocampus]] is a small, curved formation in the [[brain]] that plays an essential role in the formation of new [[memories]] and is also associated with [[learning]] and [[emotions]].


The [[Hippocampus]] is a small organ located within the brain's medial temporal lobe. It forms an important part of the limbic system, the region that regulates emotions. The hippocampus is associated mainly with memory, in particular long-term memory. It also plays an important role in spatial navigation.
==Function==
The EC-hippocampus system is primarily responsible for the consolidation of [[information]] from [[short-term memory]] to [[long-term memory]], and in [[spatial memory]] that enables [[navigation]].


[[File:Hippocampus.png|thumb|right|250px|The Hippocampus is a crucial component of the EC-Hippocampus System.]]
===Memory===
The [[hippocampus]] is involved in the formation of new [[memories]] and is essential for [[declarative memory]], which includes [[facts]] and [[events]]. The [[entorhinal cortex]] provides the [[hippocampus]] with [[sensory information]] and is involved in the initial processing of [[memory]] traces.


=== Function ===
===Navigation===
The [[entorhinal cortex]] contains specialized [[neurons]] known as [[grid cells]], which are involved in [[spatial navigation]]. These cells help the [[brain]] to create a [[cognitive map]] of the environment.


The EC-Hippocampus System is primarily involved in the formation and retrieval of memories. The EC receives inputs from various cortical areas, processes this information, and then sends it to the hippocampus. The hippocampus, in turn, integrates this information to form a coherent memory. This memory is then stored in the neocortex for long-term storage.
==Clinical Significance==
Damage to the EC-hippocampus system can result in [[memory disorders]] such as [[Alzheimer's disease]] and [[amnesia]]. The [[hippocampus]] is one of the first regions of the [[brain]] to suffer damage in [[Alzheimer's disease]], leading to the characteristic [[memory loss]] and [[disorientation]].


=== Clinical Significance ===
==Research==
Ongoing research is focused on understanding the precise mechanisms of [[memory]] encoding and retrieval in the EC-hippocampus system. Studies using [[neuroimaging]] and [[electrophysiology]] are providing insights into how [[neurons]] in this system interact during [[memory]] tasks.


Damage to the EC-Hippocampus System can result in severe memory impairments, such as those seen in [[Alzheimer's Disease]]. In Alzheimer's, neurofibrillary tangles and amyloid plaques often first appear in the EC before spreading to the hippocampus and other brain regions. This pattern of damage is thought to underlie the memory loss and disorientation that are characteristic of this disease.
==See also==
 
* [[Limbic system]]
== See Also ==
* [[Memory]]
* [[Memory]]
* [[Neuroanatomy]]
* [[Neuroscience]]
* [[Neuroscience]]
* [[Alzheimer's Disease]]
* [[Alzheimer's disease]]


== References ==
==References==
{{Reflist}}


== External Links ==
==External links==
* [https://www.wikimd.com/wiki/EC-hippocampus_system EC-hippocampus system on WikiMD]


[[Category:Neuroanatomy]]
[[Category:Neuroscience]]
[[Category:Neuroscience]]
[[Category:Memory]]
[[Category:Memory]]
[[Category:Alzheimer's Disease]]
[[Category:Brain]]
 
[[Category:Limbic system]]
{{anatomy-stub}}

Latest revision as of 21:36, 27 December 2024


General Information
Latin
Greek
TA98
TA2
FMA
Details
System Nervous system
Artery
Vein
Nerve
Lymphatic drainage
Precursor
Function
Identifiers
Clinical significance
Notes



The EC-hippocampus system is a critical component of the brain involved in memory and navigation. It primarily consists of the entorhinal cortex (EC) and the hippocampus.

Structure[edit]

The EC-hippocampus system is part of the limbic system, which is involved in emotion and memory. The entorhinal cortex serves as a major input and output structure for the hippocampus, facilitating the flow of information between the neocortex and the hippocampus.

Entorhinal Cortex[edit]

The entorhinal cortex is located in the medial temporal lobe and is a crucial hub in the brain's memory network. It is involved in the processing of spatial memory and navigation.

Hippocampus[edit]

The hippocampus is a small, curved formation in the brain that plays an essential role in the formation of new memories and is also associated with learning and emotions.

Function[edit]

The EC-hippocampus system is primarily responsible for the consolidation of information from short-term memory to long-term memory, and in spatial memory that enables navigation.

Memory[edit]

The hippocampus is involved in the formation of new memories and is essential for declarative memory, which includes facts and events. The entorhinal cortex provides the hippocampus with sensory information and is involved in the initial processing of memory traces.

Navigation[edit]

The entorhinal cortex contains specialized neurons known as grid cells, which are involved in spatial navigation. These cells help the brain to create a cognitive map of the environment.

Clinical Significance[edit]

Damage to the EC-hippocampus system can result in memory disorders such as Alzheimer's disease and amnesia. The hippocampus is one of the first regions of the brain to suffer damage in Alzheimer's disease, leading to the characteristic memory loss and disorientation.

Research[edit]

Ongoing research is focused on understanding the precise mechanisms of memory encoding and retrieval in the EC-hippocampus system. Studies using neuroimaging and electrophysiology are providing insights into how neurons in this system interact during memory tasks.

See also[edit]

References[edit]

<references group="" responsive="1"></references>


External links[edit]