Lipoblastoma: Difference between revisions
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{{Infobox medical condition | |||
[[File:Lipoblastoma.jpg|Lipoblastoma| | | name = Lipoblastoma | ||
| image = [[File:Lipoblastoma.jpg]] | |||
| caption = Gross pathology of a lipoblastoma | |||
| field = [[Oncology]], [[Pediatrics]] | |||
| synonyms = | |||
| symptoms = Soft, painless mass | |||
| complications = Rarely, compression of adjacent structures | |||
| onset = Typically in children under 3 years old | |||
| duration = | |||
| types = Lipoblastoma, Lipoblastomatosis | |||
| causes = Unknown | |||
| risks = | |||
| diagnosis = [[Histopathology]], [[Imaging studies]] | |||
| differential = [[Lipoma]], [[Myxoid liposarcoma]], [[Hibernoma]] | |||
| prevention = | |||
| treatment = [[Surgical excision]] | |||
| medication = | |||
| prognosis = Excellent with complete excision | |||
| frequency = Rare | |||
}} | |||
'''Lipoblastoma''' is a rare benign tumor of embryonal white fat that typically occurs in infants and young children. It is characterized by the proliferation of [[lipoblasts]], which are immature fat cells. Lipoblastoma is distinct from other types of [[adipose tissue]] tumors due to its unique histological features and clinical presentation. | '''Lipoblastoma''' is a rare benign tumor of embryonal white fat that typically occurs in infants and young children. It is characterized by the proliferation of [[lipoblasts]], which are immature fat cells. Lipoblastoma is distinct from other types of [[adipose tissue]] tumors due to its unique histological features and clinical presentation. | ||
== Clinical Presentation == | == Clinical Presentation == | ||
Lipoblastomas usually present as a soft, painless mass that can occur in various parts of the body, although they are most commonly found in the extremities and trunk. The tumor is typically well-circumscribed and can vary in size. Due to its benign nature, lipoblastoma does not metastasize, but it can grow rapidly, which may cause discomfort or functional impairment depending on its location. | Lipoblastomas usually present as a soft, painless mass that can occur in various parts of the body, although they are most commonly found in the extremities and trunk. The tumor is typically well-circumscribed and can vary in size. Due to its benign nature, lipoblastoma does not metastasize, but it can grow rapidly, which may cause discomfort or functional impairment depending on its location. | ||
== Pathology == | == Pathology == | ||
[[File:Lipoblast_features,_annotated.png|Lipoblast features, annotated|left|thumb]] | |||
[[File:Lipoblast_features,_annotated.png|Lipoblast features, annotated|thumb | |||
Histologically, lipoblastoma is composed of immature adipocytes, known as lipoblasts, which are embedded in a myxoid stroma. The tumor may also contain mature adipocytes and a network of capillaries. The presence of lipoblasts is a key diagnostic feature, distinguishing lipoblastoma from other adipose tissue tumors such as [[lipoma]] or [[myxoid liposarcoma]]. | Histologically, lipoblastoma is composed of immature adipocytes, known as lipoblasts, which are embedded in a myxoid stroma. The tumor may also contain mature adipocytes and a network of capillaries. The presence of lipoblasts is a key diagnostic feature, distinguishing lipoblastoma from other adipose tissue tumors such as [[lipoma]] or [[myxoid liposarcoma]]. | ||
== Diagnosis == | == Diagnosis == | ||
The diagnosis of lipoblastoma is primarily based on histological examination of the tumor tissue. Imaging studies such as [[ultrasound]], [[MRI]], or [[CT scan]] may be used to assess the extent of the tumor and its relationship to surrounding structures. However, definitive diagnosis requires a biopsy and microscopic evaluation. | The diagnosis of lipoblastoma is primarily based on histological examination of the tumor tissue. Imaging studies such as [[ultrasound]], [[MRI]], or [[CT scan]] may be used to assess the extent of the tumor and its relationship to surrounding structures. However, definitive diagnosis requires a biopsy and microscopic evaluation. | ||
== Treatment == | == Treatment == | ||
The standard treatment for lipoblastoma is surgical excision. Complete removal of the tumor is usually curative, and recurrence is rare if the tumor is entirely excised. In cases where the tumor is not completely removed, there is a risk of recurrence, necessitating further surgical intervention. | The standard treatment for lipoblastoma is surgical excision. Complete removal of the tumor is usually curative, and recurrence is rare if the tumor is entirely excised. In cases where the tumor is not completely removed, there is a risk of recurrence, necessitating further surgical intervention. | ||
== Prognosis == | == Prognosis == | ||
The prognosis for patients with lipoblastoma is excellent, given its benign nature. With appropriate surgical management, most patients experience complete resolution of the condition without long-term complications. | The prognosis for patients with lipoblastoma is excellent, given its benign nature. With appropriate surgical management, most patients experience complete resolution of the condition without long-term complications. | ||
== See also == | |||
== | |||
* [[Lipoma]] | * [[Lipoma]] | ||
* [[Liposarcoma]] | * [[Liposarcoma]] | ||
* [[Adipose tissue]] | * [[Adipose tissue]] | ||
* [[Benign tumor]] | * [[Benign tumor]] | ||
[[Category:Benign neoplasms]] | [[Category:Benign neoplasms]] | ||
[[Category:Pediatric cancers]] | [[Category:Pediatric cancers]] | ||
[[Category:Soft tissue tumors]] | [[Category:Soft tissue tumors]] | ||
Latest revision as of 04:14, 8 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Lipoblastoma | |
|---|---|
| |
| Synonyms | |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Soft, painless mass |
| Complications | Rarely, compression of adjacent structures |
| Onset | Typically in children under 3 years old |
| Duration | |
| Types | Lipoblastoma, Lipoblastomatosis |
| Causes | Unknown |
| Risks | |
| Diagnosis | Histopathology, Imaging studies |
| Differential diagnosis | Lipoma, Myxoid liposarcoma, Hibernoma |
| Prevention | |
| Treatment | Surgical excision |
| Medication | |
| Prognosis | Excellent with complete excision |
| Frequency | Rare |
| Deaths | N/A |
Lipoblastoma is a rare benign tumor of embryonal white fat that typically occurs in infants and young children. It is characterized by the proliferation of lipoblasts, which are immature fat cells. Lipoblastoma is distinct from other types of adipose tissue tumors due to its unique histological features and clinical presentation.
Clinical Presentation[edit]
Lipoblastomas usually present as a soft, painless mass that can occur in various parts of the body, although they are most commonly found in the extremities and trunk. The tumor is typically well-circumscribed and can vary in size. Due to its benign nature, lipoblastoma does not metastasize, but it can grow rapidly, which may cause discomfort or functional impairment depending on its location.
Pathology[edit]
Histologically, lipoblastoma is composed of immature adipocytes, known as lipoblasts, which are embedded in a myxoid stroma. The tumor may also contain mature adipocytes and a network of capillaries. The presence of lipoblasts is a key diagnostic feature, distinguishing lipoblastoma from other adipose tissue tumors such as lipoma or myxoid liposarcoma.
Diagnosis[edit]
The diagnosis of lipoblastoma is primarily based on histological examination of the tumor tissue. Imaging studies such as ultrasound, MRI, or CT scan may be used to assess the extent of the tumor and its relationship to surrounding structures. However, definitive diagnosis requires a biopsy and microscopic evaluation.
Treatment[edit]
The standard treatment for lipoblastoma is surgical excision. Complete removal of the tumor is usually curative, and recurrence is rare if the tumor is entirely excised. In cases where the tumor is not completely removed, there is a risk of recurrence, necessitating further surgical intervention.
Prognosis[edit]
The prognosis for patients with lipoblastoma is excellent, given its benign nature. With appropriate surgical management, most patients experience complete resolution of the condition without long-term complications.
