Pseudoallergy: Difference between revisions
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{{Infobox medical condition | |||
| name = Pseudoallergy | |||
| synonyms = Non-allergic hypersensitivity | |||
| field = [[Allergy and Immunology]] | |||
| symptoms = [[Urticaria]], [[angioedema]], [[anaphylactoid reactions]] | |||
| onset = Varies depending on exposure | |||
| duration = Variable, often short-term | |||
| causes = Non-immunological activation of [[mast cells]] | |||
| risks = [[Aspirin]], [[NSAIDs]], [[food additives]] | |||
| diagnosis = Clinical evaluation, exclusion of [[IgE-mediated allergy]] | |||
| differential = [[True allergy]], [[intolerance]] | |||
| treatment = Avoidance of triggers, [[antihistamines]] | |||
| frequency = Common, varies by population | |||
}} | |||
'''Pseudoallergy''' is a type of [[hypersensitivity]] reaction that mimics an [[allergy]], but is not caused by the immune system's response to an allergen. Instead, it is often caused by non-specific activation of certain immune system cells. | '''Pseudoallergy''' is a type of [[hypersensitivity]] reaction that mimics an [[allergy]], but is not caused by the immune system's response to an allergen. Instead, it is often caused by non-specific activation of certain immune system cells. | ||
== Causes == | == Causes == | ||
Pseudoallergies can be triggered by a variety of substances, including certain [[food additives]], [[medications]], and [[chemicals]]. Unlike true allergies, pseudoallergies do not involve the immune system's production of [[IgE]] antibodies, and they do not require prior exposure to the triggering substance. | Pseudoallergies can be triggered by a variety of substances, including certain [[food additives]], [[medications]], and [[chemicals]]. Unlike true allergies, pseudoallergies do not involve the immune system's production of [[IgE]] antibodies, and they do not require prior exposure to the triggering substance. | ||
== Symptoms == | == Symptoms == | ||
The symptoms of a pseudoallergy can closely resemble those of a true allergy, and can include [[hives]], [[itching]], [[nasal congestion]], and [[anaphylaxis]]. However, the onset of symptoms is typically more rapid in a pseudoallergy, often occurring within minutes of exposure to the triggering substance. | The symptoms of a pseudoallergy can closely resemble those of a true allergy, and can include [[hives]], [[itching]], [[nasal congestion]], and [[anaphylaxis]]. However, the onset of symptoms is typically more rapid in a pseudoallergy, often occurring within minutes of exposure to the triggering substance. | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosing a pseudoallergy can be challenging, as the symptoms closely resemble those of a true allergy. However, a key difference is that pseudoallergies do not show up on [[allergy tests]], as they do not involve the production of IgE antibodies. Instead, diagnosis is typically based on a detailed medical history and the exclusion of other potential causes. | Diagnosing a pseudoallergy can be challenging, as the symptoms closely resemble those of a true allergy. However, a key difference is that pseudoallergies do not show up on [[allergy tests]], as they do not involve the production of IgE antibodies. Instead, diagnosis is typically based on a detailed medical history and the exclusion of other potential causes. | ||
== Treatment == | == Treatment == | ||
Treatment for pseudoallergies typically involves avoiding the triggering substance. In some cases, medications such as [[antihistamines]] or [[corticosteroids]] may be used to manage symptoms. However, these treatments do not cure the pseudoallergy, and symptoms may recur if the individual is exposed to the triggering substance again. | Treatment for pseudoallergies typically involves avoiding the triggering substance. In some cases, medications such as [[antihistamines]] or [[corticosteroids]] may be used to manage symptoms. However, these treatments do not cure the pseudoallergy, and symptoms may recur if the individual is exposed to the triggering substance again. | ||
== See also == | == See also == | ||
* [[Allergy]] | * [[Allergy]] | ||
* [[Hypersensitivity]] | * [[Hypersensitivity]] | ||
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* [[Food additive]] | * [[Food additive]] | ||
* [[Medication]] | * [[Medication]] | ||
[[Category:Medical conditions]] | [[Category:Medical conditions]] | ||
[[Category:Allergies]] | [[Category:Allergies]] | ||
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{{stub}} | {{stub}} | ||
{{No image}} | {{No image}} | ||
Latest revision as of 06:15, 4 April 2025
| Pseudoallergy | |
|---|---|
| Synonyms | Non-allergic hypersensitivity |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Urticaria, angioedema, anaphylactoid reactions |
| Complications | N/A |
| Onset | Varies depending on exposure |
| Duration | Variable, often short-term |
| Types | N/A |
| Causes | Non-immunological activation of mast cells |
| Risks | Aspirin, NSAIDs, food additives |
| Diagnosis | Clinical evaluation, exclusion of IgE-mediated allergy |
| Differential diagnosis | True allergy, intolerance |
| Prevention | N/A |
| Treatment | Avoidance of triggers, antihistamines |
| Medication | N/A |
| Prognosis | N/A |
| Frequency | Common, varies by population |
| Deaths | N/A |
Pseudoallergy is a type of hypersensitivity reaction that mimics an allergy, but is not caused by the immune system's response to an allergen. Instead, it is often caused by non-specific activation of certain immune system cells.
Causes[edit]
Pseudoallergies can be triggered by a variety of substances, including certain food additives, medications, and chemicals. Unlike true allergies, pseudoallergies do not involve the immune system's production of IgE antibodies, and they do not require prior exposure to the triggering substance.
Symptoms[edit]
The symptoms of a pseudoallergy can closely resemble those of a true allergy, and can include hives, itching, nasal congestion, and anaphylaxis. However, the onset of symptoms is typically more rapid in a pseudoallergy, often occurring within minutes of exposure to the triggering substance.
Diagnosis[edit]
Diagnosing a pseudoallergy can be challenging, as the symptoms closely resemble those of a true allergy. However, a key difference is that pseudoallergies do not show up on allergy tests, as they do not involve the production of IgE antibodies. Instead, diagnosis is typically based on a detailed medical history and the exclusion of other potential causes.
Treatment[edit]
Treatment for pseudoallergies typically involves avoiding the triggering substance. In some cases, medications such as antihistamines or corticosteroids may be used to manage symptoms. However, these treatments do not cure the pseudoallergy, and symptoms may recur if the individual is exposed to the triggering substance again.
