Beclamide: Difference between revisions
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{{Short description|A drug used in the treatment of epilepsy}} | |||
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| verifiedrevid = 477002282 | |||
| IUPAC_name = 3-chloro-N-ethyl-N-phenylpropanamide | |||
| image = Beclamide.svg | |||
| image_size = 200px | |||
| image_alt = Structural formula of Beclamide | |||
}} | |||
'''Beclamide''' is a [[medication]] primarily used in the treatment of [[epilepsy]]. It is classified as an [[anticonvulsant]] and works by stabilizing the electrical activity in the brain. Beclamide is particularly effective in managing [[generalized tonic-clonic seizures]] and [[partial seizures]]. | |||
Beclamide | |||
== | ==Pharmacology== | ||
The exact mechanism of action | Beclamide functions by modulating the activity of [[neurotransmitters]] in the brain, which helps to prevent the abnormal electrical discharges that lead to seizures. The exact mechanism of action is not fully understood, but it is believed to involve the enhancement of [[GABAergic]] inhibition and the reduction of [[glutamatergic]] excitation. | ||
== | ==Chemical Properties== | ||
[[File:Beclamide.svg|thumb|right|Structural formula of Beclamide]] | |||
Beclamide is chemically known as 3-chloro-N-ethyl-N-phenylpropanamide. It is a white crystalline powder that is soluble in water and alcohol. The molecular formula is C<sub>11</sub>H<sub>14</sub>ClNO, and it has a molecular weight of 211.69 g/mol. | |||
== | ==Clinical Use== | ||
Beclamide | Beclamide is used in the management of epilepsy, particularly in patients who experience generalized tonic-clonic and partial seizures. It is often prescribed when other anticonvulsants are not effective or cause undesirable side effects. The dosage of beclamide is tailored to the individual needs of the patient, and it is usually administered orally. | ||
== | ==Side Effects== | ||
Common side effects of beclamide include [[drowsiness]], [[dizziness]], and [[gastrointestinal disturbances]] such as [[nausea]] and [[vomiting]]. In some cases, patients may experience [[allergic reactions]], [[skin rashes]], or [[blood dyscrasias]]. It is important for patients to be monitored regularly by their healthcare provider while taking beclamide. | |||
== | ==History== | ||
Beclamide | Beclamide was first introduced in the mid-20th century as an anticonvulsant. It has been used in various countries for the treatment of epilepsy, although its use has declined with the development of newer anticonvulsants that have more favorable side effect profiles. | ||
== | ==Related pages== | ||
* [[Epilepsy]] | |||
* [[Anticonvulsant]] | |||
* [[Generalized tonic-clonic seizure]] | |||
* [[Partial seizure]] | |||
[[Category:Anticonvulsants]] | [[Category:Anticonvulsants]] | ||
[[Category: | [[Category:Chloroacetamides]] | ||
[[Category: | [[Category:Epilepsy treatment]] | ||
Latest revision as of 10:52, 23 March 2025
A drug used in the treatment of epilepsy
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Beclamide is a medication primarily used in the treatment of epilepsy. It is classified as an anticonvulsant and works by stabilizing the electrical activity in the brain. Beclamide is particularly effective in managing generalized tonic-clonic seizures and partial seizures.
Pharmacology[edit]
Beclamide functions by modulating the activity of neurotransmitters in the brain, which helps to prevent the abnormal electrical discharges that lead to seizures. The exact mechanism of action is not fully understood, but it is believed to involve the enhancement of GABAergic inhibition and the reduction of glutamatergic excitation.
Chemical Properties[edit]
Beclamide is chemically known as 3-chloro-N-ethyl-N-phenylpropanamide. It is a white crystalline powder that is soluble in water and alcohol. The molecular formula is C11H14ClNO, and it has a molecular weight of 211.69 g/mol.
Clinical Use[edit]
Beclamide is used in the management of epilepsy, particularly in patients who experience generalized tonic-clonic and partial seizures. It is often prescribed when other anticonvulsants are not effective or cause undesirable side effects. The dosage of beclamide is tailored to the individual needs of the patient, and it is usually administered orally.
Side Effects[edit]
Common side effects of beclamide include drowsiness, dizziness, and gastrointestinal disturbances such as nausea and vomiting. In some cases, patients may experience allergic reactions, skin rashes, or blood dyscrasias. It is important for patients to be monitored regularly by their healthcare provider while taking beclamide.
History[edit]
Beclamide was first introduced in the mid-20th century as an anticonvulsant. It has been used in various countries for the treatment of epilepsy, although its use has declined with the development of newer anticonvulsants that have more favorable side effect profiles.
