Orbital lymphoma: Difference between revisions
From WikiMD's Wellness Encyclopedia
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{{Infobox medical condition | |||
[[File:Orbital_lymphoma.png| | | name = Orbital lymphoma | ||
| image = [[File:Orbital_lymphoma.png|250px]] | |||
| caption = CT scan showing orbital lymphoma | |||
| field = [[Ophthalmology]], [[Oncology]] | |||
| symptoms = [[Proptosis]], [[diplopia]], [[vision loss]], [[eyelid swelling]] | |||
| complications = [[Vision impairment]], [[orbital cellulitis]] | |||
| onset = Typically in [[adulthood]] | |||
| duration = Variable, depending on treatment | |||
| types = [[MALT lymphoma]], [[Diffuse large B-cell lymphoma]], [[Follicular lymphoma]] | |||
| causes = [[Genetic mutations]], [[environmental factors]] | |||
| risks = [[Age]], [[immunosuppression]], [[autoimmune diseases]] | |||
| diagnosis = [[Biopsy]], [[imaging studies]] | |||
| differential = [[Orbital pseudotumor]], [[thyroid eye disease]], [[orbital cellulitis]] | |||
| treatment = [[Radiation therapy]], [[chemotherapy]], [[surgery]] | |||
| prognosis = Generally good with treatment, varies by type | |||
| frequency = Rare | |||
}} | |||
'''Orbital lymphoma''' is a type of [[non-Hodgkin lymphoma]] that occurs in the [[orbit (anatomy)|orbit]], the bony cavity in the skull where the [[eye]] and its appendages are situated. It is a rare condition that can affect the [[eye socket]], leading to various ocular and systemic symptoms. | '''Orbital lymphoma''' is a type of [[non-Hodgkin lymphoma]] that occurs in the [[orbit (anatomy)|orbit]], the bony cavity in the skull where the [[eye]] and its appendages are situated. It is a rare condition that can affect the [[eye socket]], leading to various ocular and systemic symptoms. | ||
== Pathophysiology == | == Pathophysiology == | ||
Orbital lymphoma is characterized by the proliferation of malignant [[lymphocytes]] within the orbital tissues. The most common type of orbital lymphoma is [[mucosa-associated lymphoid tissue (MALT) lymphoma]], but other types such as [[diffuse large B-cell lymphoma]] and [[follicular lymphoma]] can also occur. | Orbital lymphoma is characterized by the proliferation of malignant [[lymphocytes]] within the orbital tissues. The most common type of orbital lymphoma is [[mucosa-associated lymphoid tissue (MALT) lymphoma]], but other types such as [[diffuse large B-cell lymphoma]] and [[follicular lymphoma]] can also occur. | ||
== Clinical Presentation == | == Clinical Presentation == | ||
Patients with orbital lymphoma may present with a variety of symptoms, including: | Patients with orbital lymphoma may present with a variety of symptoms, including: | ||
* [[Proptosis]] (bulging of the eye) | * [[Proptosis]] (bulging of the eye) | ||
* [[Diplopia]] (double vision) | * [[Diplopia]] (double vision) | ||
| Line 18: | Line 28: | ||
* [[Vision impairment]] | * [[Vision impairment]] | ||
* [[Periorbital swelling]] | * [[Periorbital swelling]] | ||
These symptoms result from the mass effect of the lymphoma within the confined space of the orbit. | These symptoms result from the mass effect of the lymphoma within the confined space of the orbit. | ||
== Diagnosis == | == Diagnosis == | ||
The diagnosis of orbital lymphoma typically involves: | The diagnosis of orbital lymphoma typically involves: | ||
* [[Clinical examination]] | * [[Clinical examination]] | ||
* [[Imaging studies]] such as [[CT scan]] or [[MRI]] of the orbit | * [[Imaging studies]] such as [[CT scan]] or [[MRI]] of the orbit | ||
* [[Biopsy]] of the orbital mass for histopathological examination | * [[Biopsy]] of the orbital mass for histopathological examination | ||
== Treatment == | == Treatment == | ||
Treatment options for orbital lymphoma depend on the type and stage of the lymphoma and may include: | Treatment options for orbital lymphoma depend on the type and stage of the lymphoma and may include: | ||
* [[Radiation therapy]] | * [[Radiation therapy]] | ||
* [[Chemotherapy]] | * [[Chemotherapy]] | ||
* [[Immunotherapy]] | * [[Immunotherapy]] | ||
In some cases, a combination of these treatments may be used to achieve the best outcome. | In some cases, a combination of these treatments may be used to achieve the best outcome. | ||
== Prognosis == | == Prognosis == | ||
The prognosis for patients with orbital lymphoma varies depending on the type and stage of the disease. MALT lymphoma generally has a good prognosis with appropriate treatment, while more aggressive types like diffuse large B-cell lymphoma may have a more guarded prognosis. | The prognosis for patients with orbital lymphoma varies depending on the type and stage of the disease. MALT lymphoma generally has a good prognosis with appropriate treatment, while more aggressive types like diffuse large B-cell lymphoma may have a more guarded prognosis. | ||
== See also == | |||
== | |||
* [[Lymphoma]] | * [[Lymphoma]] | ||
* [[Non-Hodgkin lymphoma]] | * [[Non-Hodgkin lymphoma]] | ||
* [[Eye diseases]] | * [[Eye diseases]] | ||
* [[Ophthalmology]] | * [[Ophthalmology]] | ||
[[Category:Ophthalmology]] | [[Category:Ophthalmology]] | ||
[[Category:Lymphoma]] | [[Category:Lymphoma]] | ||
Latest revision as of 06:16, 8 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Orbital lymphoma | |
|---|---|
| |
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Proptosis, diplopia, vision loss, eyelid swelling |
| Complications | Vision impairment, orbital cellulitis |
| Onset | Typically in adulthood |
| Duration | Variable, depending on treatment |
| Types | MALT lymphoma, Diffuse large B-cell lymphoma, Follicular lymphoma |
| Causes | Genetic mutations, environmental factors |
| Risks | Age, immunosuppression, autoimmune diseases |
| Diagnosis | Biopsy, imaging studies |
| Differential diagnosis | Orbital pseudotumor, thyroid eye disease, orbital cellulitis |
| Prevention | N/A |
| Treatment | Radiation therapy, chemotherapy, surgery |
| Medication | N/A |
| Prognosis | Generally good with treatment, varies by type |
| Frequency | Rare |
| Deaths | N/A |
Orbital lymphoma is a type of non-Hodgkin lymphoma that occurs in the orbit, the bony cavity in the skull where the eye and its appendages are situated. It is a rare condition that can affect the eye socket, leading to various ocular and systemic symptoms.
Pathophysiology[edit]
Orbital lymphoma is characterized by the proliferation of malignant lymphocytes within the orbital tissues. The most common type of orbital lymphoma is mucosa-associated lymphoid tissue (MALT) lymphoma, but other types such as diffuse large B-cell lymphoma and follicular lymphoma can also occur.
Clinical Presentation[edit]
Patients with orbital lymphoma may present with a variety of symptoms, including:
- Proptosis (bulging of the eye)
- Diplopia (double vision)
- Ptosis (drooping of the eyelid)
- Vision impairment
- Periorbital swelling
These symptoms result from the mass effect of the lymphoma within the confined space of the orbit.
Diagnosis[edit]
The diagnosis of orbital lymphoma typically involves:
- Clinical examination
- Imaging studies such as CT scan or MRI of the orbit
- Biopsy of the orbital mass for histopathological examination
Treatment[edit]
Treatment options for orbital lymphoma depend on the type and stage of the lymphoma and may include:
In some cases, a combination of these treatments may be used to achieve the best outcome.
Prognosis[edit]
The prognosis for patients with orbital lymphoma varies depending on the type and stage of the disease. MALT lymphoma generally has a good prognosis with appropriate treatment, while more aggressive types like diffuse large B-cell lymphoma may have a more guarded prognosis.
