5F-CUMYL-P7AICA: Difference between revisions

From WikiMD's Wellness Encyclopedia

CSV import
 
CSV import
 
Line 3: Line 3:
| verifiedfields = changed
| verifiedfields = changed
| verifiedrevid = 477002547
| verifiedrevid = 477002547
| IUPAC_name = 1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indole-3-carboxamide
| image = 5F-CUMYL-P7AICA_Structure.svg
| image = 5F-CUMYL-P7AICA_Structure.svg
| image_size = 200px
| image_alt = Chemical structure of 5F-CUMYL-P7AICA
| IUPAC_name = 1-(5-Fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indole-3-carboxamide
| CAS_number = 1400742-14-7
| ChemSpiderID = 58191434
| UNII = 7F5F9N0R6H
| PubChem = 119025345
| C=23
| H=27
| F=1
| N=2
| O=1
}}
}}


'''5F-CUMYL-P7AICA''' is a synthetic cannabinoid that has been used in scientific research and is known for its potent agonistic activity at the [[cannabinoid receptor]]s. It is part of a class of compounds that are often used in the development of new [[pharmacological]] agents.
'''5F-CUMYL-P7AICA''' is a synthetic [[cannabinoid]] that has been used in [[designer drug]]s. It is a potent agonist of the [[cannabinoid receptor]]s, which are part of the [[endocannabinoid system]].


==Chemical Structure==
==Chemical structure and properties==
5F-CUMYL-P7AICA is characterized by its indole core structure, which is substituted at the 1-position with a 5-fluoropentyl chain and at the 3-position with a carboxamide group. The carboxamide is further substituted with a cumyl group, which is a 2-phenylpropan-2-yl moiety. This structure is similar to other synthetic cannabinoids, which often feature a core indole or indazole structure with various substituents.
[[File:5F-CUMYL-P7AICA_Structure.svg|thumb|right|Chemical structure of 5F-CUMYL-P7AICA]]
5F-CUMYL-P7AICA is chemically classified as an indole-based synthetic cannabinoid. Its IUPAC name is 1-(5-Fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indole-3-carboxamide. The compound features a fluorinated pentyl chain, which is a common modification in synthetic cannabinoids to enhance potency and metabolic stability.


==Pharmacology==
==Pharmacology==
5F-CUMYL-P7AICA acts as a potent agonist at the [[CB1 receptor|CB1]] and [[CB2 receptor|CB2]] cannabinoid receptors. These receptors are part of the [[endocannabinoid system]], which plays a role in regulating various physiological processes including pain sensation, mood, and appetite. The compound's high affinity for these receptors makes it a subject of interest in the study of cannabinoid receptor pharmacology.
5F-CUMYL-P7AICA acts as a full agonist at the [[CB1 receptor]] and [[CB2 receptor]], which are the primary receptors of the endocannabinoid system. These receptors are involved in a variety of physiological processes including pain sensation, mood, and memory. The activation of these receptors by synthetic cannabinoids can lead to effects similar to those of [[tetrahydrocannabinol]] (THC), the active component of [[cannabis]].


==Legal Status==
==Effects and toxicity==
The legal status of 5F-CUMYL-P7AICA varies by country. In some jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. Researchers must be aware of the legal restrictions in their country when working with this compound.
The effects of 5F-CUMYL-P7AICA are similar to those of other synthetic cannabinoids, which can include euphoria, altered perception, and relaxation. However, synthetic cannabinoids can also cause severe adverse effects such as [[tachycardia]], [[hypertension]], [[nausea]], [[vomiting]], [[anxiety]], and [[psychosis]]. The toxicity of 5F-CUMYL-P7AICA is not well-documented, but it is likely to be similar to other synthetic cannabinoids, which have been associated with serious health risks and fatalities.


==Safety and Toxicology==
==Legal status==
As with many synthetic cannabinoids, the safety profile of 5F-CUMYL-P7AICA is not well-established. There is limited data on its toxicity, but synthetic cannabinoids have been associated with adverse effects such as [[tachycardia]], [[hypertension]], and [[hallucinations]]. Caution is advised when handling this compound in a research setting.
The legal status of 5F-CUMYL-P7AICA varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. It is often included in legislation targeting synthetic cannabinoids and other [[novel psychoactive substances]].


==Related Compounds==
==Synthesis==
5F-CUMYL-P7AICA is related to other synthetic cannabinoids such as [[5F-ADB]], [[AB-FUBINACA]], and [[JWH-018]]. These compounds share similar structural features and pharmacological properties, making them useful for comparative studies in cannabinoid research.
The synthesis of 5F-CUMYL-P7AICA involves the reaction of an indole-3-carboxylic acid derivative with a fluorinated alkyl halide, followed by amide formation with an appropriate amine. The synthetic routes for these compounds are often designed to be straightforward to facilitate clandestine production.


==Related pages==
==Related pages==
* [[Synthetic cannabinoids]]
* [[Synthetic cannabinoids]]
* [[Cannabinoid receptor]]
* [[Cannabinoid receptor]]
* [[Designer drug]]
* [[Endocannabinoid system]]
* [[Endocannabinoid system]]
==Gallery==
<gallery>
File:5F-CUMYL-P7AICA_Structure.svg|Chemical structure of 5F-CUMYL-P7AICA
</gallery>


[[Category:Synthetic cannabinoids]]
[[Category:Synthetic cannabinoids]]
[[Category:Indoles]]
[[Category:Designer drugs]]
[[Category:Fluoroarenes]]

Latest revision as of 06:12, 16 February 2025

Synthetic cannabinoid


5F-CUMYL-P7AICA
File:5F-CUMYL-P7AICA Structure.svg
INN
Drug class
Routes of administration
Pregnancy category
Bioavailability
Metabolism
Elimination half-life
Excretion
Legal status
CAS Number 1400742-14-7
PubChem 119025345
DrugBank
ChemSpider 58191434
KEGG


5F-CUMYL-P7AICA is a synthetic cannabinoid that has been used in designer drugs. It is a potent agonist of the cannabinoid receptors, which are part of the endocannabinoid system.

Chemical structure and properties[edit]

File:5F-CUMYL-P7AICA Structure.svg
Chemical structure of 5F-CUMYL-P7AICA

5F-CUMYL-P7AICA is chemically classified as an indole-based synthetic cannabinoid. Its IUPAC name is 1-(5-Fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indole-3-carboxamide. The compound features a fluorinated pentyl chain, which is a common modification in synthetic cannabinoids to enhance potency and metabolic stability.

Pharmacology[edit]

5F-CUMYL-P7AICA acts as a full agonist at the CB1 receptor and CB2 receptor, which are the primary receptors of the endocannabinoid system. These receptors are involved in a variety of physiological processes including pain sensation, mood, and memory. The activation of these receptors by synthetic cannabinoids can lead to effects similar to those of tetrahydrocannabinol (THC), the active component of cannabis.

Effects and toxicity[edit]

The effects of 5F-CUMYL-P7AICA are similar to those of other synthetic cannabinoids, which can include euphoria, altered perception, and relaxation. However, synthetic cannabinoids can also cause severe adverse effects such as tachycardia, hypertension, nausea, vomiting, anxiety, and psychosis. The toxicity of 5F-CUMYL-P7AICA is not well-documented, but it is likely to be similar to other synthetic cannabinoids, which have been associated with serious health risks and fatalities.

Legal status[edit]

The legal status of 5F-CUMYL-P7AICA varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. It is often included in legislation targeting synthetic cannabinoids and other novel psychoactive substances.

Synthesis[edit]

The synthesis of 5F-CUMYL-P7AICA involves the reaction of an indole-3-carboxylic acid derivative with a fluorinated alkyl halide, followed by amide formation with an appropriate amine. The synthetic routes for these compounds are often designed to be straightforward to facilitate clandestine production.

Related pages[edit]