25I-NBOH: Difference between revisions
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== 25I-NBOH == | |||
[[File:2C-I-NBOH-skeletal.svg|thumb|right|Chemical structure of 25I-NBOH]] | |||
25I-NBOH, also known as 2C-I-NBOH, is a potent [[psychedelic]] compound that belongs to the [[N-benzylphenethylamine]] class. It is a derivative of the phenethylamine 2C-I and is closely related to the [[NBOMe]] series of compounds. 25I-NBOH is known for its strong binding affinity to the [[serotonin receptor|5-HT2A receptor]], which is believed to be responsible for its psychedelic effects. | |||
==Chemical | == Chemical Structure == | ||
25I-NBOH is chemically | 25I-NBOH is chemically similar to 2C-I, with the addition of a 2-hydroxybenzyl group attached to the nitrogen atom of the phenethylamine backbone. This modification increases its potency and alters its pharmacological profile compared to its parent compound, 2C-I. | ||
==Pharmacology== | == Pharmacology == | ||
25I-NBOH | The primary mechanism of action for 25I-NBOH is its agonistic activity at the 5-HT2A receptor, a subtype of the [[serotonin receptor]] that is implicated in the modulation of mood, perception, and cognition. The compound's high affinity for this receptor is thought to underlie its psychedelic effects, which can include altered visual and auditory perceptions, changes in thought patterns, and emotional experiences. | ||
==Effects== | == Effects == | ||
The effects of 25I-NBOH are similar to those of other psychedelics, such as [[LSD]] and [[psilocybin]]. Users | The effects of 25I-NBOH are similar to those of other psychedelics, such as [[LSD]] and [[psilocybin]]. Users may experience visual hallucinations, synesthesia, and a distorted sense of time. The intensity and duration of these effects can vary depending on the dose and individual sensitivity. | ||
== | == Safety and Toxicity == | ||
As with many research chemicals, the safety profile of 25I-NBOH is not well-established. There have been reports of adverse effects, including [[vasoconstriction]], [[tachycardia]], and [[hypertension]], particularly at higher doses. Due to its potency and the potential for overdose, caution is advised when handling this compound. | |||
== | == Legal Status == | ||
The legal status of 25I-NBOH varies by country. In some jurisdictions, it is classified as a controlled substance, while in others, it may be legal or unregulated. It is important to be aware of the local laws regarding the possession and use of this compound. | |||
==Related | == Related Compounds == | ||
* [[2C-I]] | * [[2C-I]] | ||
* [[ | * [[25I-NBOMe]] | ||
* [[ | * [[2C-B]] | ||
* [[25B-NBOH]] | |||
== See Also == | |||
* [[Psychedelic drug]] | * [[Psychedelic drug]] | ||
* [[Serotonin receptor]] | |||
* [[Phenethylamine]] | |||
== Related Pages == | |||
* [[NBOMe series]] | |||
* [[Psychedelic research chemicals]] | |||
[[Category:Psychedelic phenethylamines]] | [[Category:Psychedelic phenethylamines]] | ||
[[Category:Serotonin receptor agonists]] | [[Category:Serotonin receptor agonists]] | ||
Latest revision as of 10:51, 15 February 2025
25I-NBOH[edit]
25I-NBOH, also known as 2C-I-NBOH, is a potent psychedelic compound that belongs to the N-benzylphenethylamine class. It is a derivative of the phenethylamine 2C-I and is closely related to the NBOMe series of compounds. 25I-NBOH is known for its strong binding affinity to the 5-HT2A receptor, which is believed to be responsible for its psychedelic effects.
Chemical Structure[edit]
25I-NBOH is chemically similar to 2C-I, with the addition of a 2-hydroxybenzyl group attached to the nitrogen atom of the phenethylamine backbone. This modification increases its potency and alters its pharmacological profile compared to its parent compound, 2C-I.
Pharmacology[edit]
The primary mechanism of action for 25I-NBOH is its agonistic activity at the 5-HT2A receptor, a subtype of the serotonin receptor that is implicated in the modulation of mood, perception, and cognition. The compound's high affinity for this receptor is thought to underlie its psychedelic effects, which can include altered visual and auditory perceptions, changes in thought patterns, and emotional experiences.
Effects[edit]
The effects of 25I-NBOH are similar to those of other psychedelics, such as LSD and psilocybin. Users may experience visual hallucinations, synesthesia, and a distorted sense of time. The intensity and duration of these effects can vary depending on the dose and individual sensitivity.
Safety and Toxicity[edit]
As with many research chemicals, the safety profile of 25I-NBOH is not well-established. There have been reports of adverse effects, including vasoconstriction, tachycardia, and hypertension, particularly at higher doses. Due to its potency and the potential for overdose, caution is advised when handling this compound.
Legal Status[edit]
The legal status of 25I-NBOH varies by country. In some jurisdictions, it is classified as a controlled substance, while in others, it may be legal or unregulated. It is important to be aware of the local laws regarding the possession and use of this compound.
