Tangeretin: Difference between revisions

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'''Tangeretin''' is a polymethoxylated flavone, a type of flavonoid, that is found in citrus peels and in some herbs. It is most notably found in tangerines, from which it derives its name. Tangeretin has been studied for its potential health benefits, including its anti-inflammatory, anti-cancer, and neuroprotective properties.
{{short description|A flavonoid found in citrus peels}}
{{DISPLAYTITLE:Tangeretin}}
 
[[File:Tangeritin.svg|thumb|right|Chemical structure of Tangeretin]]
 
'''Tangeretin''' is a [[flavonoid]] compound found predominantly in the [[peel]]s of [[citrus]] fruits, such as [[tangerines]] and [[oranges]]. It is a type of [[polymethoxylated flavone]], which is characterized by the presence of multiple methoxy groups attached to its flavone backbone. Tangeretin is known for its potential [[health benefits]] and is a subject of interest in [[nutritional science]] and [[pharmacology]].


==Chemical Structure==
==Chemical Structure==
Tangeretin is a polymethoxylated flavone, meaning it contains multiple methoxy groups attached to its flavone backbone. Its chemical formula is C20H20O7, and its systematic name is 4',5,6,7,8-Pentamethoxyflavone.
Tangeretin is a [[polymethoxylated flavone]], which means it has several methoxy groups attached to its flavone structure. The chemical formula of tangeretin is C<sub>20</sub>H<sub>20</sub>O<sub>7</sub>. Its structure consists of a flavone backbone with five methoxy groups, which contribute to its [[hydrophobic]] nature and influence its [[biological activity]].


==Sources==
==Sources==
Tangeretin is found in the peels of citrus fruits, particularly tangerines, but also in oranges and grapefruits. It is also found in some herbs, such as [[Artemisia]] and [[Oregano]].
Tangeretin is primarily found in the [[peel]]s of [[citrus]] fruits, particularly in [[tangerines]], [[oranges]], and other related species. The concentration of tangeretin is higher in the peel compared to the [[pulp]] or [[juice]] of the fruit. This compound is part of the natural defense mechanism of the fruit, protecting it from [[pathogens]] and [[pests]].
 
==Biological Activity==
Tangeretin has been studied for its potential [[antioxidant]], [[anti-inflammatory]], and [[anticancer]] properties. It is believed to modulate various [[cellular pathways]] and may have a role in [[preventing]] or [[treating]] certain [[diseases]].
 
===Antioxidant Properties===
As an [[antioxidant]], tangeretin helps in neutralizing [[free radicals]] and reducing [[oxidative stress]] in the body. This property is important in protecting [[cells]] from damage and may contribute to the prevention of [[chronic diseases]] such as [[cardiovascular disease]] and [[cancer]].


==Health Benefits==
===Anti-inflammatory Effects===
===Anti-inflammatory Properties===
Tangeretin has been shown to exhibit [[anti-inflammatory]] effects by inhibiting the production of [[pro-inflammatory cytokines]] and mediators. This can be beneficial in managing [[inflammatory conditions]] and [[autoimmune diseases]].
Tangeretin has been shown to have anti-inflammatory properties. It inhibits the production of pro-inflammatory cytokines, which are proteins that promote inflammation.


===Anti-cancer Properties===
===Anticancer Potential===
Tangeretin has been studied for its potential anti-cancer properties. It has been shown to inhibit the growth of various types of cancer cells, including breast, lung, and colon cancer cells.
Research suggests that tangeretin may have [[anticancer]] properties, as it can induce [[apoptosis]] in [[cancer cells]] and inhibit their [[proliferation]]. It may also enhance the effectiveness of certain [[chemotherapeutic agents]].


===Neuroprotective Properties===
==Applications==
Tangeretin has also been studied for its potential neuroprotective properties. It has been shown to protect neurons from damage caused by oxidative stress, which is thought to play a role in neurodegenerative diseases like [[Alzheimer's disease]] and [[Parkinson's disease]].
Tangeretin is used in various [[dietary supplements]] and [[functional foods]] due to its potential health benefits. It is also being explored for its use in [[cosmetics]] and [[pharmaceuticals]].


==Safety and Side Effects==
==Safety and Toxicity==
While tangeretin is generally considered safe, it can interact with certain medications, particularly those metabolized by the liver. It can also cause allergic reactions in some individuals.
While tangeretin is generally considered safe when consumed as part of a [[balanced diet]], high doses or concentrated extracts may have [[adverse effects]]. It is important to consider potential [[interactions]] with [[medications]] and consult with a [[healthcare professional]] before using tangeretin supplements.


==See Also==
==Related Pages==
* [[Flavonoids]]
* [[Flavonoid]]
* [[Citrus]]
* [[Citrus]]
* [[Antioxidant]]
* [[Anti-inflammatory]]
* [[Anti-inflammatory]]
* [[Anti-cancer]]
* [[Cancer prevention]]
* [[Neuroprotection]]
 
==References==
<references />


[[Category:Flavonoids]]
[[Category:Flavonoids]]
[[Category:Phytochemicals]]
[[Category:Citrus]]
[[Category:Pharmacology]]
[[Category:Antioxidants]]
 
{{pharmacology-stub}}

Latest revision as of 04:05, 13 February 2025

A flavonoid found in citrus peels



Chemical structure of Tangeretin

Tangeretin is a flavonoid compound found predominantly in the peels of citrus fruits, such as tangerines and oranges. It is a type of polymethoxylated flavone, which is characterized by the presence of multiple methoxy groups attached to its flavone backbone. Tangeretin is known for its potential health benefits and is a subject of interest in nutritional science and pharmacology.

Chemical Structure[edit]

Tangeretin is a polymethoxylated flavone, which means it has several methoxy groups attached to its flavone structure. The chemical formula of tangeretin is C20H20O7. Its structure consists of a flavone backbone with five methoxy groups, which contribute to its hydrophobic nature and influence its biological activity.

Sources[edit]

Tangeretin is primarily found in the peels of citrus fruits, particularly in tangerines, oranges, and other related species. The concentration of tangeretin is higher in the peel compared to the pulp or juice of the fruit. This compound is part of the natural defense mechanism of the fruit, protecting it from pathogens and pests.

Biological Activity[edit]

Tangeretin has been studied for its potential antioxidant, anti-inflammatory, and anticancer properties. It is believed to modulate various cellular pathways and may have a role in preventing or treating certain diseases.

Antioxidant Properties[edit]

As an antioxidant, tangeretin helps in neutralizing free radicals and reducing oxidative stress in the body. This property is important in protecting cells from damage and may contribute to the prevention of chronic diseases such as cardiovascular disease and cancer.

Anti-inflammatory Effects[edit]

Tangeretin has been shown to exhibit anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines and mediators. This can be beneficial in managing inflammatory conditions and autoimmune diseases.

Anticancer Potential[edit]

Research suggests that tangeretin may have anticancer properties, as it can induce apoptosis in cancer cells and inhibit their proliferation. It may also enhance the effectiveness of certain chemotherapeutic agents.

Applications[edit]

Tangeretin is used in various dietary supplements and functional foods due to its potential health benefits. It is also being explored for its use in cosmetics and pharmaceuticals.

Safety and Toxicity[edit]

While tangeretin is generally considered safe when consumed as part of a balanced diet, high doses or concentrated extracts may have adverse effects. It is important to consider potential interactions with medications and consult with a healthcare professional before using tangeretin supplements.

Related Pages[edit]