Pleomorphic T-cell lymphoma: Difference between revisions
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{{Infobox medical condition | |||
| name = Pleomorphic T-cell lymphoma | |||
| synonyms = | |||
| specialty = [[Hematology]], [[Oncology]] | |||
| symptoms = [[Lymphadenopathy]], [[fever]], [[weight loss]], [[night sweats]] | |||
| onset = | |||
| duration = | |||
| types = | |||
| causes = Unknown | |||
| risks = | |||
| diagnosis = [[Biopsy]], [[immunophenotyping]], [[genetic testing]] | |||
| differential = [[Other types of T-cell lymphoma]], [[B-cell lymphoma]] | |||
| prevention = | |||
| treatment = [[Chemotherapy]], [[radiation therapy]], [[stem cell transplant]] | |||
| medication = | |||
| prognosis = Variable, depends on stage and response to treatment | |||
| frequency = Rare | |||
}} | |||
'''Pleomorphic T-cell lymphoma''' is a type of [[non-Hodgkin lymphoma]] that affects the [[T cells]] in the [[immune system]]. It is characterized by a diverse range of cell shapes and sizes, hence the term "pleomorphic". This lymphoma is considered a subtype of [[peripheral T-cell lymphoma]], which is a group of rare and aggressive [[lymphomas]] that develop from mature T cells. | '''Pleomorphic T-cell lymphoma''' is a type of [[non-Hodgkin lymphoma]] that affects the [[T cells]] in the [[immune system]]. It is characterized by a diverse range of cell shapes and sizes, hence the term "pleomorphic". This lymphoma is considered a subtype of [[peripheral T-cell lymphoma]], which is a group of rare and aggressive [[lymphomas]] that develop from mature T cells. | ||
== Symptoms == | == Symptoms == | ||
The symptoms of pleomorphic T-cell lymphoma can vary widely, but may include [[fever]], [[night sweats]], [[weight loss]], and [[fatigue]]. Swollen [[lymph nodes]] are also a common symptom. | The symptoms of pleomorphic T-cell lymphoma can vary widely, but may include [[fever]], [[night sweats]], [[weight loss]], and [[fatigue]]. Swollen [[lymph nodes]] are also a common symptom. | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of pleomorphic T-cell lymphoma typically involves a [[biopsy]] of an affected lymph node or other tissue. The biopsy sample is then examined under a microscope to identify the presence of abnormal T cells. Other tests, such as [[blood tests]], [[imaging tests]], and a [[bone marrow biopsy]], may also be used to help confirm the diagnosis and determine the extent of the disease. | Diagnosis of pleomorphic T-cell lymphoma typically involves a [[biopsy]] of an affected lymph node or other tissue. The biopsy sample is then examined under a microscope to identify the presence of abnormal T cells. Other tests, such as [[blood tests]], [[imaging tests]], and a [[bone marrow biopsy]], may also be used to help confirm the diagnosis and determine the extent of the disease. | ||
== Treatment == | == Treatment == | ||
Treatment for pleomorphic T-cell lymphoma often involves [[chemotherapy]], with or without [[radiation therapy]]. In some cases, a [[stem cell transplant]] may be considered. The choice of treatment depends on a number of factors, including the patient's overall health, the stage of the disease, and the patient's personal preferences. | Treatment for pleomorphic T-cell lymphoma often involves [[chemotherapy]], with or without [[radiation therapy]]. In some cases, a [[stem cell transplant]] may be considered. The choice of treatment depends on a number of factors, including the patient's overall health, the stage of the disease, and the patient's personal preferences. | ||
== Prognosis == | == Prognosis == | ||
The prognosis for pleomorphic T-cell lymphoma can vary widely, depending on factors such as the patient's age, overall health, and the stage of the disease at diagnosis. In general, however, this type of lymphoma is considered to be aggressive and difficult to treat. | The prognosis for pleomorphic T-cell lymphoma can vary widely, depending on factors such as the patient's age, overall health, and the stage of the disease at diagnosis. In general, however, this type of lymphoma is considered to be aggressive and difficult to treat. | ||
== See also == | == See also == | ||
* [[Non-Hodgkin lymphoma]] | * [[Non-Hodgkin lymphoma]] | ||
| Line 18: | Line 32: | ||
* [[T cells]] | * [[T cells]] | ||
* [[Immune system]] | * [[Immune system]] | ||
[[Category:Non-Hodgkin lymphoma]] | [[Category:Non-Hodgkin lymphoma]] | ||
[[Category:Peripheral T-cell lymphoma]] | [[Category:Peripheral T-cell lymphoma]] | ||
[[Category:T cells]] | [[Category:T cells]] | ||
[[Category:Immune system]] | [[Category:Immune system]] | ||
{{stub}} | {{stub}} | ||
{{No image}} | {{No image}} | ||
Latest revision as of 04:42, 4 April 2025
| Pleomorphic T-cell lymphoma | |
|---|---|
| Synonyms | |
| Pronounce | N/A |
| Specialty | Hematology, Oncology |
| Symptoms | Lymphadenopathy, fever, weight loss, night sweats |
| Complications | N/A |
| Onset | |
| Duration | |
| Types | |
| Causes | Unknown |
| Risks | |
| Diagnosis | Biopsy, immunophenotyping, genetic testing |
| Differential diagnosis | Other types of T-cell lymphoma, B-cell lymphoma |
| Prevention | |
| Treatment | Chemotherapy, radiation therapy, stem cell transplant |
| Medication | |
| Prognosis | Variable, depends on stage and response to treatment |
| Frequency | Rare |
| Deaths | N/A |
Pleomorphic T-cell lymphoma is a type of non-Hodgkin lymphoma that affects the T cells in the immune system. It is characterized by a diverse range of cell shapes and sizes, hence the term "pleomorphic". This lymphoma is considered a subtype of peripheral T-cell lymphoma, which is a group of rare and aggressive lymphomas that develop from mature T cells.
Symptoms[edit]
The symptoms of pleomorphic T-cell lymphoma can vary widely, but may include fever, night sweats, weight loss, and fatigue. Swollen lymph nodes are also a common symptom.
Diagnosis[edit]
Diagnosis of pleomorphic T-cell lymphoma typically involves a biopsy of an affected lymph node or other tissue. The biopsy sample is then examined under a microscope to identify the presence of abnormal T cells. Other tests, such as blood tests, imaging tests, and a bone marrow biopsy, may also be used to help confirm the diagnosis and determine the extent of the disease.
Treatment[edit]
Treatment for pleomorphic T-cell lymphoma often involves chemotherapy, with or without radiation therapy. In some cases, a stem cell transplant may be considered. The choice of treatment depends on a number of factors, including the patient's overall health, the stage of the disease, and the patient's personal preferences.
Prognosis[edit]
The prognosis for pleomorphic T-cell lymphoma can vary widely, depending on factors such as the patient's age, overall health, and the stage of the disease at diagnosis. In general, however, this type of lymphoma is considered to be aggressive and difficult to treat.
