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{{Short description|A benign odontogenic tumor}}
{{SI}}  
 
{{Infobox medical condition
'''Ameloblastic fibroma''' is a rare, benign [[odontogenic tumor]] that typically occurs in the [[jaw]]s. It is characterized by the proliferation of both epithelial and mesenchymal components, resembling the developing [[tooth germ]]. This tumor is most commonly found in children and young adults, with a slight predilection for males.
| name                    = Ameloblastic fibroma
 
| image                  = [[File:Enamelmineralization11-17-05.jpg|250px]]
==Pathophysiology==
| caption                = Histological image of ameloblastic fibroma
Ameloblastic fibroma arises from the [[odontogenic epithelium]] and the [[ectomesenchyme]], which are tissues involved in the formation of teeth. The tumor consists of strands and islands of odontogenic epithelium embedded in a cellular ectomesenchymal tissue that resembles the dental papilla. Unlike other odontogenic tumors, ameloblastic fibroma does not produce [[dentin]] or [[enamel]].
| field                  = [[Oral and maxillofacial pathology]]
 
| synonyms                =
==Clinical Presentation==
| pronunciation          =
Patients with ameloblastic fibroma often present with a painless swelling in the jaw, most commonly in the posterior region of the [[mandible]]. The tumor can cause expansion of the cortical bone and may lead to facial asymmetry. In some cases, it may be associated with an unerupted tooth.
| specialty              = [[Dentistry]], [[Oral and maxillofacial surgery]]
 
| symptoms                = Swelling, pain, delayed tooth eruption
==Diagnosis==
| onset                  = Usually in the first two decades of life
The diagnosis of ameloblastic fibroma is primarily based on [[radiographic]] and [[histopathological]] examination. Radiographically, the tumor appears as a well-defined radiolucent lesion, often associated with an impacted tooth. Histologically, it is characterized by the presence of odontogenic epithelium in a mesenchymal stroma.
| duration                =
 
| types                  =
==Treatment==
| causes                  = Unknown
The treatment of choice for ameloblastic fibroma is surgical excision. The extent of surgery depends on the size and location of the tumor. Conservative surgical approaches are preferred to preserve the surrounding structures, but complete removal is necessary to prevent recurrence.
| risks                  =
 
| diagnosis              = [[Histopathology]], [[Radiography]]
==Prognosis==
| differential            = [[Ameloblastoma]], [[Odontogenic myxoma]], [[Odontoma]]
The prognosis for patients with ameloblastic fibroma is generally good, with a low recurrence rate following complete surgical excision. However, there is a potential for the tumor to transform into an [[ameloblastic fibrosarcoma]], a malignant counterpart, which necessitates careful long-term follow-up.
| prevention              =
 
| treatment              = Surgical excision
==Related pages==
| medication              =
| prognosis              = Good with complete excision
| frequency              = Rare
| deaths                  =
}}
{{Short description|A rare benign odontogenic tumor}}
== Ameloblastic Fibroma ==
[[File:Enamelmineralization11-17-05.jpg|Enamel mineralization process|thumb|left]]
'''Ameloblastic fibroma''' is a rare, benign [[odontogenic tumor]] that arises from the [[odontogenic epithelium]] and the [[mesenchymal]] tissue of the [[tooth germ]]. It is characterized by the proliferation of both epithelial and mesenchymal components, which distinguishes it from other odontogenic tumors.
== Clinical Presentation ==
Ameloblastic fibromas typically present as a painless swelling in the jaw, often discovered incidentally on radiographs. They are most commonly found in the posterior region of the [[mandible]], although they can also occur in the [[maxilla]]. The condition is more prevalent in children and young adults, with a slight male predominance.
== Radiographic Features ==
On radiographic examination, ameloblastic fibromas appear as well-defined radiolucent lesions. They may be unilocular or multilocular, and the borders are often corticated. The lesion can cause displacement of adjacent teeth and may be associated with an unerupted tooth.
== Histopathology ==
Histologically, ameloblastic fibromas consist of strands and islands of odontogenic epithelium resembling the [[ameloblastoma]], set within a cellular mesenchymal stroma that resembles the dental papilla. The epithelial component may form structures similar to the enamel organ, but without enamel formation.
== Treatment ==
The treatment of choice for ameloblastic fibroma is surgical excision. Due to the potential for recurrence, complete removal with a margin of healthy tissue is recommended. In some cases, more aggressive surgical approaches may be necessary to prevent recurrence.
== Prognosis ==
The prognosis for ameloblastic fibroma is generally good, with a low rate of malignant transformation. However, there is a risk of recurrence if the lesion is not completely excised. Long-term follow-up is advised to monitor for any signs of recurrence or malignant transformation into an [[ameloblastic fibrosarcoma]].
== See Also ==
* [[Odontogenic tumor]]
* [[Odontogenic tumor]]
* [[Ameloblastoma]]
* [[Ameloblastoma]]
* [[Odontogenic myxoma]]
* [[Odontogenic myxoma]]
 
* [[Dental anatomy]]
[[File:Enamelmineralization11-17-05.jpg|Enamel mineralization process|thumb|right]]
 
[[Category:Odontogenic tumors]]
[[Category:Odontogenic tumors]]
[[Category:Benign neoplasms]]
[[Category:Oral pathology]]

Latest revision as of 22:33, 5 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Ameloblastic fibroma
Synonyms
Pronounce N/A
Specialty Dentistry, Oral and maxillofacial surgery
Symptoms Swelling, pain, delayed tooth eruption
Complications N/A
Onset Usually in the first two decades of life
Duration
Types
Causes Unknown
Risks
Diagnosis Histopathology, Radiography
Differential diagnosis Ameloblastoma, Odontogenic myxoma, Odontoma
Prevention
Treatment Surgical excision
Medication
Prognosis Good with complete excision
Frequency Rare
Deaths


A rare benign odontogenic tumor


Ameloblastic Fibroma[edit]

Enamel mineralization process

Ameloblastic fibroma is a rare, benign odontogenic tumor that arises from the odontogenic epithelium and the mesenchymal tissue of the tooth germ. It is characterized by the proliferation of both epithelial and mesenchymal components, which distinguishes it from other odontogenic tumors.

Clinical Presentation[edit]

Ameloblastic fibromas typically present as a painless swelling in the jaw, often discovered incidentally on radiographs. They are most commonly found in the posterior region of the mandible, although they can also occur in the maxilla. The condition is more prevalent in children and young adults, with a slight male predominance.

Radiographic Features[edit]

On radiographic examination, ameloblastic fibromas appear as well-defined radiolucent lesions. They may be unilocular or multilocular, and the borders are often corticated. The lesion can cause displacement of adjacent teeth and may be associated with an unerupted tooth.

Histopathology[edit]

Histologically, ameloblastic fibromas consist of strands and islands of odontogenic epithelium resembling the ameloblastoma, set within a cellular mesenchymal stroma that resembles the dental papilla. The epithelial component may form structures similar to the enamel organ, but without enamel formation.

Treatment[edit]

The treatment of choice for ameloblastic fibroma is surgical excision. Due to the potential for recurrence, complete removal with a margin of healthy tissue is recommended. In some cases, more aggressive surgical approaches may be necessary to prevent recurrence.

Prognosis[edit]

The prognosis for ameloblastic fibroma is generally good, with a low rate of malignant transformation. However, there is a risk of recurrence if the lesion is not completely excised. Long-term follow-up is advised to monitor for any signs of recurrence or malignant transformation into an ameloblastic fibrosarcoma.

See Also[edit]