Meckel's diverticulum: Difference between revisions
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{{Infobox medical condition | |||
| name = Meckel's diverticulum | |||
| image = [[File:Diverticule_de_Meckel.jpg]] | |||
| caption = Meckel's diverticulum as seen in a surgical specimen | |||
| field = [[Gastroenterology]] | |||
| symptoms = [[Abdominal pain]], [[gastrointestinal bleeding]], [[intestinal obstruction]] | |||
| complications = [[Perforation (medical)|Perforation]], [[peritonitis]], [[intussusception]] | |||
| onset = Congenital | |||
| duration = Lifelong | |||
| causes = [[Congenital]] | |||
| risks = [[Male]] gender, [[family history]] | |||
| diagnosis = [[Technetium-99m scan]], [[CT scan]], [[MRI]] | |||
| differential = [[Appendicitis]], [[Crohn's disease]], [[peptic ulcer disease]] | |||
| treatment = [[Surgical resection]] | |||
| medication = [[Antibiotics]] for infection | |||
| prognosis = Generally good with treatment | |||
| frequency = 2% of the population | |||
| deaths = Rare | |||
}} | |||
{{Short description|Congenital anomaly of the gastrointestinal tract}} | {{Short description|Congenital anomaly of the gastrointestinal tract}} | ||
'''Meckel's diverticulum''' is a congenital anomaly of the [[gastrointestinal tract]] that results from an incomplete obliteration of the [[vitelline duct]] (also known as the omphalomesenteric duct) during embryonic development. It is the most common congenital defect of the gastrointestinal tract, occurring in approximately 2% of the population. | '''Meckel's diverticulum''' is a congenital anomaly of the [[gastrointestinal tract]] that results from an incomplete obliteration of the [[vitelline duct]] (also known as the omphalomesenteric duct) during embryonic development. It is the most common congenital defect of the gastrointestinal tract, occurring in approximately 2% of the population. | ||
==Anatomy and Pathophysiology== | ==Anatomy and Pathophysiology== | ||
Meckel's diverticulum is a true diverticulum, meaning it contains all layers of the intestinal wall, including the mucosa, submucosa, and muscularis propria. It is typically located in the [[ileum]], about 40 to 100 cm proximal to the [[ileocecal valve]]. The diverticulum is usually 3 to 5 cm in length, but it can vary significantly. | Meckel's diverticulum is a true diverticulum, meaning it contains all layers of the intestinal wall, including the mucosa, submucosa, and muscularis propria. It is typically located in the [[ileum]], about 40 to 100 cm proximal to the [[ileocecal valve]]. The diverticulum is usually 3 to 5 cm in length, but it can vary significantly. | ||
The presence of ectopic tissue, such as [[gastric mucosa]] or [[pancreatic tissue]], within the diverticulum can lead to complications. Gastric mucosa can secrete acid, leading to [[ulceration]] and [[bleeding]]. | The presence of ectopic tissue, such as [[gastric mucosa]] or [[pancreatic tissue]], within the diverticulum can lead to complications. Gastric mucosa can secrete acid, leading to [[ulceration]] and [[bleeding]]. | ||
==Clinical Presentation== | ==Clinical Presentation== | ||
[[File:Meckel's_Diverticulum_AFIP.jpg|thumb | [[File:Meckel's_Diverticulum_AFIP.jpg|left|thumb|Pathological specimen of Meckel's diverticulum]] | ||
Most individuals with Meckel's diverticulum are asymptomatic. However, when symptoms do occur, they often present in childhood. The classic presentation includes painless rectal bleeding, which may be due to ulceration of the ectopic gastric mucosa. | Most individuals with Meckel's diverticulum are asymptomatic. However, when symptoms do occur, they often present in childhood. The classic presentation includes painless rectal bleeding, which may be due to ulceration of the ectopic gastric mucosa. | ||
Other potential complications include [[intestinal obstruction]], [[volvulus]], and [[intussusception]]. Inflammation of the diverticulum, known as Meckel's diverticulitis, can mimic [[appendicitis]]. | Other potential complications include [[intestinal obstruction]], [[volvulus]], and [[intussusception]]. Inflammation of the diverticulum, known as Meckel's diverticulitis, can mimic [[appendicitis]]. | ||
==Diagnosis== | ==Diagnosis== | ||
[[File:Meckel's_Diverticulum_by_Technetium-99m_Pertechnetate_Scan.jpg|thumb | [[File:Meckel's_Diverticulum_by_Technetium-99m_Pertechnetate_Scan.jpg|left|thumb|Meckel's diverticulum as seen on a technetium-99m pertechnetate scan]] | ||
The diagnosis of Meckel's diverticulum can be challenging, especially in asymptomatic individuals. When symptomatic, a [[technetium-99m pertechnetate scan]] (Meckel's scan) is often used to detect ectopic gastric mucosa. This scan is particularly useful in children presenting with unexplained gastrointestinal bleeding. | The diagnosis of Meckel's diverticulum can be challenging, especially in asymptomatic individuals. When symptomatic, a [[technetium-99m pertechnetate scan]] (Meckel's scan) is often used to detect ectopic gastric mucosa. This scan is particularly useful in children presenting with unexplained gastrointestinal bleeding. | ||
Other diagnostic modalities include [[CT scan]], [[MRI]], and [[endoscopy]], although these are less specific. | Other diagnostic modalities include [[CT scan]], [[MRI]], and [[endoscopy]], although these are less specific. | ||
==Treatment== | ==Treatment== | ||
The treatment of Meckel's diverticulum depends on the presence and type of symptoms. Asymptomatic diverticula are often left untreated. However, symptomatic diverticula, especially those causing bleeding or obstruction, typically require surgical intervention. | The treatment of Meckel's diverticulum depends on the presence and type of symptoms. Asymptomatic diverticula are often left untreated. However, symptomatic diverticula, especially those causing bleeding or obstruction, typically require surgical intervention. | ||
Surgical options include diverticulectomy, where only the diverticulum is removed, or segmental resection, where a portion of the ileum is removed along with the diverticulum. | Surgical options include diverticulectomy, where only the diverticulum is removed, or segmental resection, where a portion of the ileum is removed along with the diverticulum. | ||
==Prognosis== | ==Prognosis== | ||
The prognosis for individuals with Meckel's diverticulum is generally excellent, especially when complications are promptly addressed. Surgical treatment of symptomatic diverticula usually results in complete resolution of symptoms. | The prognosis for individuals with Meckel's diverticulum is generally excellent, especially when complications are promptly addressed. Surgical treatment of symptomatic diverticula usually results in complete resolution of symptoms. | ||
==See also== | |||
== | |||
* [[Appendicitis]] | * [[Appendicitis]] | ||
* [[Intestinal obstruction]] | * [[Intestinal obstruction]] | ||
* [[Gastrointestinal bleeding]] | * [[Gastrointestinal bleeding]] | ||
[[Category:Congenital disorders of digestive system]] | [[Category:Congenital disorders of digestive system]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
Latest revision as of 04:24, 8 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's medical weight loss NYC, sleep center NYC
Philadelphia medical weight loss and Philadelphia sleep clinics
| Meckel's diverticulum | |
|---|---|
| File:Diverticule de Meckel.jpg | |
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Abdominal pain, gastrointestinal bleeding, intestinal obstruction |
| Complications | Perforation, peritonitis, intussusception |
| Onset | Congenital |
| Duration | Lifelong |
| Types | N/A |
| Causes | Congenital |
| Risks | Male gender, family history |
| Diagnosis | Technetium-99m scan, CT scan, MRI |
| Differential diagnosis | Appendicitis, Crohn's disease, peptic ulcer disease |
| Prevention | N/A |
| Treatment | Surgical resection |
| Medication | Antibiotics for infection |
| Prognosis | Generally good with treatment |
| Frequency | 2% of the population |
| Deaths | Rare |
Congenital anomaly of the gastrointestinal tract
Meckel's diverticulum is a congenital anomaly of the gastrointestinal tract that results from an incomplete obliteration of the vitelline duct (also known as the omphalomesenteric duct) during embryonic development. It is the most common congenital defect of the gastrointestinal tract, occurring in approximately 2% of the population.
Anatomy and Pathophysiology[edit]
Meckel's diverticulum is a true diverticulum, meaning it contains all layers of the intestinal wall, including the mucosa, submucosa, and muscularis propria. It is typically located in the ileum, about 40 to 100 cm proximal to the ileocecal valve. The diverticulum is usually 3 to 5 cm in length, but it can vary significantly. The presence of ectopic tissue, such as gastric mucosa or pancreatic tissue, within the diverticulum can lead to complications. Gastric mucosa can secrete acid, leading to ulceration and bleeding.
Clinical Presentation[edit]
Most individuals with Meckel's diverticulum are asymptomatic. However, when symptoms do occur, they often present in childhood. The classic presentation includes painless rectal bleeding, which may be due to ulceration of the ectopic gastric mucosa. Other potential complications include intestinal obstruction, volvulus, and intussusception. Inflammation of the diverticulum, known as Meckel's diverticulitis, can mimic appendicitis.
Diagnosis[edit]
The diagnosis of Meckel's diverticulum can be challenging, especially in asymptomatic individuals. When symptomatic, a technetium-99m pertechnetate scan (Meckel's scan) is often used to detect ectopic gastric mucosa. This scan is particularly useful in children presenting with unexplained gastrointestinal bleeding. Other diagnostic modalities include CT scan, MRI, and endoscopy, although these are less specific.
Treatment[edit]
The treatment of Meckel's diverticulum depends on the presence and type of symptoms. Asymptomatic diverticula are often left untreated. However, symptomatic diverticula, especially those causing bleeding or obstruction, typically require surgical intervention. Surgical options include diverticulectomy, where only the diverticulum is removed, or segmental resection, where a portion of the ileum is removed along with the diverticulum.
Prognosis[edit]
The prognosis for individuals with Meckel's diverticulum is generally excellent, especially when complications are promptly addressed. Surgical treatment of symptomatic diverticula usually results in complete resolution of symptoms.
