Pathologic fracture: Difference between revisions
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{{Infobox medical condition | |||
| name = Pathologic fracture | |||
| image = [[File:Pathologische_Fraktur_bei_Metastase_Nierencell-Ca_im_Humerus.jpg|250px]] | |||
| caption = Pathologic fracture of the humerus due to metastasis from renal cell carcinoma | |||
| field = [[Orthopedics]], [[Oncology]] | |||
| symptoms = [[Bone pain]], [[swelling]], [[deformity]], [[loss of function]] | |||
| complications = [[Nonunion]], [[malunion]], [[infection]] | |||
| onset = Sudden, often with minimal or no trauma | |||
| duration = Varies, depending on underlying cause and treatment | |||
| causes = [[Osteoporosis]], [[bone metastasis]], [[osteomyelitis]], [[Paget's disease of bone]], [[osteogenesis imperfecta]] | |||
| risks = [[Cancer]], [[chronic steroid use]], [[bone diseases]] | |||
| diagnosis = [[X-ray]], [[CT scan]], [[MRI]], [[bone scan]] | |||
| differential = [[Traumatic fracture]], [[bone cyst]], [[benign bone tumor]] | |||
| treatment = [[Surgery]], [[radiation therapy]], [[chemotherapy]], [[bisphosphonates]] | |||
| prognosis = Depends on underlying condition and treatment | |||
| frequency = Common in patients with [[cancer]] or [[osteoporosis]] | |||
}} | |||
[[File:Blausen_0686_Osteoporosis_01.png|Osteoporosis illustration|thumb|left]] | |||
A '''[[pathologic fracture]]''' is a type of [[bone fracture]] that occurs in a bone affected by a disease, making it weaker than normal bone. This can be due to a variety of conditions, including [[osteoporosis]], [[cancer]], [[infection]], or certain inherited bone disorders. | A '''[[pathologic fracture]]''' is a type of [[bone fracture]] that occurs in a bone affected by a disease, making it weaker than normal bone. This can be due to a variety of conditions, including [[osteoporosis]], [[cancer]], [[infection]], or certain inherited bone disorders. | ||
==Causes== | ==Causes== | ||
Pathologic fractures can be caused by a variety of conditions. The most common cause is [[metastatic bone disease]], where cancer cells spread from their original site to the bones. Other causes include [[osteoporosis]], a condition that weakens bones and makes them more likely to break, and [[Paget's disease of bone]], a chronic disorder that can result in enlarged and misshapen bones. Infections, such as [[osteomyelitis]], can also cause pathologic fractures. | Pathologic fractures can be caused by a variety of conditions. The most common cause is [[metastatic bone disease]], where cancer cells spread from their original site to the bones. Other causes include [[osteoporosis]], a condition that weakens bones and makes them more likely to break, and [[Paget's disease of bone]], a chronic disorder that can result in enlarged and misshapen bones. Infections, such as [[osteomyelitis]], can also cause pathologic fractures. | ||
==Symptoms== | ==Symptoms== | ||
The symptoms of a pathologic fracture can vary depending on the location and severity of the fracture. Common symptoms include pain at the site of the fracture, swelling, and difficulty moving the affected area. In some cases, a pathologic fracture may be the first sign of an underlying bone disease. | The symptoms of a pathologic fracture can vary depending on the location and severity of the fracture. Common symptoms include pain at the site of the fracture, swelling, and difficulty moving the affected area. In some cases, a pathologic fracture may be the first sign of an underlying bone disease. | ||
==Diagnosis== | ==Diagnosis== | ||
Diagnosis of a pathologic fracture typically involves a combination of physical examination, medical history, and imaging tests. [[X-ray]]s are often the first test done, but other imaging tests such as [[CT scan]]s, [[MRI]]s, or [[bone scan]]s may be used to provide more detailed information about the fracture and the underlying disease. | Diagnosis of a pathologic fracture typically involves a combination of physical examination, medical history, and imaging tests. [[X-ray]]s are often the first test done, but other imaging tests such as [[CT scan]]s, [[MRI]]s, or [[bone scan]]s may be used to provide more detailed information about the fracture and the underlying disease. | ||
==Treatment== | ==Treatment== | ||
Treatment for a pathologic fracture depends on the cause of the fracture and the patient's overall health. Treatment options may include [[surgery]], [[radiation therapy]], [[chemotherapy]], or [[bisphosphonates]], which are medications that can help strengthen bones. In some cases, a [[bone graft]] may be used to help repair the fracture. | Treatment for a pathologic fracture depends on the cause of the fracture and the patient's overall health. Treatment options may include [[surgery]], [[radiation therapy]], [[chemotherapy]], or [[bisphosphonates]], which are medications that can help strengthen bones. In some cases, a [[bone graft]] may be used to help repair the fracture. | ||
==Prognosis== | ==Prognosis== | ||
The prognosis for a pathologic fracture depends on a variety of factors, including the underlying cause of the fracture, the patient's overall health, and the location and severity of the fracture. In general, pathologic fractures can take longer to heal than normal fractures, and they may require more intensive treatment. | The prognosis for a pathologic fracture depends on a variety of factors, including the underlying cause of the fracture, the patient's overall health, and the location and severity of the fracture. In general, pathologic fractures can take longer to heal than normal fractures, and they may require more intensive treatment. | ||
==See also== | ==See also== | ||
* [[Bone fracture]] | * [[Bone fracture]] | ||
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* [[Metastatic bone disease]] | * [[Metastatic bone disease]] | ||
* [[Paget's disease of bone]] | * [[Paget's disease of bone]] | ||
[[Category:Orthopedic clinical science]] | [[Category:Orthopedic clinical science]] | ||
[[Category:Pathology]] | [[Category:Pathology]] | ||
| Line 34: | Line 39: | ||
{{Orthopedic-stub}} | {{Orthopedic-stub}} | ||
{{Pathology-stub}} | {{Pathology-stub}} | ||
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| Pathologic fracture | |
|---|---|
| File:Pathologische Fraktur bei Metastase Nierencell-Ca im Humerus.jpg | |
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Bone pain, swelling, deformity, loss of function |
| Complications | Nonunion, malunion, infection |
| Onset | Sudden, often with minimal or no trauma |
| Duration | Varies, depending on underlying cause and treatment |
| Types | N/A |
| Causes | Osteoporosis, bone metastasis, osteomyelitis, Paget's disease of bone, osteogenesis imperfecta |
| Risks | Cancer, chronic steroid use, bone diseases |
| Diagnosis | X-ray, CT scan, MRI, bone scan |
| Differential diagnosis | Traumatic fracture, bone cyst, benign bone tumor |
| Prevention | N/A |
| Treatment | Surgery, radiation therapy, chemotherapy, bisphosphonates |
| Medication | N/A |
| Prognosis | Depends on underlying condition and treatment |
| Frequency | Common in patients with cancer or osteoporosis |
| Deaths | N/A |
A pathologic fracture is a type of bone fracture that occurs in a bone affected by a disease, making it weaker than normal bone. This can be due to a variety of conditions, including osteoporosis, cancer, infection, or certain inherited bone disorders.
Causes[edit]
Pathologic fractures can be caused by a variety of conditions. The most common cause is metastatic bone disease, where cancer cells spread from their original site to the bones. Other causes include osteoporosis, a condition that weakens bones and makes them more likely to break, and Paget's disease of bone, a chronic disorder that can result in enlarged and misshapen bones. Infections, such as osteomyelitis, can also cause pathologic fractures.
Symptoms[edit]
The symptoms of a pathologic fracture can vary depending on the location and severity of the fracture. Common symptoms include pain at the site of the fracture, swelling, and difficulty moving the affected area. In some cases, a pathologic fracture may be the first sign of an underlying bone disease.
Diagnosis[edit]
Diagnosis of a pathologic fracture typically involves a combination of physical examination, medical history, and imaging tests. X-rays are often the first test done, but other imaging tests such as CT scans, MRIs, or bone scans may be used to provide more detailed information about the fracture and the underlying disease.
Treatment[edit]
Treatment for a pathologic fracture depends on the cause of the fracture and the patient's overall health. Treatment options may include surgery, radiation therapy, chemotherapy, or bisphosphonates, which are medications that can help strengthen bones. In some cases, a bone graft may be used to help repair the fracture.
Prognosis[edit]
The prognosis for a pathologic fracture depends on a variety of factors, including the underlying cause of the fracture, the patient's overall health, and the location and severity of the fracture. In general, pathologic fractures can take longer to heal than normal fractures, and they may require more intensive treatment.
See also[edit]
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