Atrophoderma: Difference between revisions

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{{SI}}
{{Infobox medical condition
| name                    = Atrophoderma
| image                  = [[File:Steroid_Atrophy_Hands.png|250px]]
| caption                = Example of skin atrophy on the hands
| synonyms                = Atrophoderma of Pasini and Pierini
| specialty              = [[Dermatology]]
| symptoms                = Thinning of the skin, loss of skin elasticity
| complications          = [[Scleroderma]], [[Morphea]]
| onset                  = Typically in adolescence or early adulthood
| duration                = Chronic
| causes                  = Unknown, possibly autoimmune
| risks                  = Family history, [[autoimmune disease]]
| diagnosis              = Clinical examination, [[skin biopsy]]
| differential            = [[Morphea]], [[Lichen sclerosus]], [[Anetoderma]]
| treatment              = [[Topical corticosteroids]], [[Phototherapy]], [[Immunosuppressive drugs]]
| prognosis              = Variable, may stabilize or progress
| frequency              = Rare
}}
{{DISPLAYTITLE:Atrophoderma}}
{{DISPLAYTITLE:Atrophoderma}}
== Overview ==
[[File:Steroid_Atrophy_Hands.png|thumb|right|Atrophoderma on the hands]]
'''Atrophoderma''' is a term used to describe a group of skin conditions characterized by localized or diffuse thinning of the skin. This condition can result from a variety of causes, including genetic factors, inflammatory processes, or the use of certain medications such as corticosteroids.
'''Atrophoderma''' is a term used to describe a group of skin conditions characterized by localized or diffuse thinning of the skin. This condition can result from a variety of causes, including genetic factors, inflammatory processes, or the use of certain medications such as corticosteroids.
== Etiology ==
== Etiology ==
Atrophoderma can be classified based on its underlying cause:
Atrophoderma can be classified based on its underlying cause:
* '''[[Atrophoderma of Pasini and Pierini]]''': A form of atrophoderma that presents as hyperpigmented, depressed patches on the skin, often on the trunk.
* '''[[Atrophoderma of Pasini and Pierini]]''': A form of atrophoderma that presents as hyperpigmented, depressed patches on the skin, often on the trunk.
* '''[[Steroid-induced atrophy]]''': Prolonged use of topical or systemic corticosteroids can lead to thinning of the skin, known as steroid atrophy.
* '''[[Steroid-induced atrophy]]''': Prolonged use of topical or systemic corticosteroids can lead to thinning of the skin, known as steroid atrophy.
* '''[[Anetoderma]]''': Characterized by localized areas of slack skin due to loss of elastic tissue.
* '''[[Anetoderma]]''': Characterized by localized areas of slack skin due to loss of elastic tissue.
== Clinical Presentation ==
== Clinical Presentation ==
The clinical features of atrophoderma vary depending on the specific type and cause. Common features include:
The clinical features of atrophoderma vary depending on the specific type and cause. Common features include:
* Thinning of the skin
* Thinning of the skin
* Depressed or indented patches
* Depressed or indented patches
* Changes in skin pigmentation
* Changes in skin pigmentation
== Diagnosis ==
== Diagnosis ==
Diagnosis of atrophoderma is primarily clinical, based on the appearance of the skin. A [[skin biopsy]] may be performed to confirm the diagnosis and rule out other conditions.
Diagnosis of atrophoderma is primarily clinical, based on the appearance of the skin. A [[skin biopsy]] may be performed to confirm the diagnosis and rule out other conditions.
== Management ==
== Management ==
Management of atrophoderma depends on the underlying cause. For steroid-induced atrophy, discontinuation or reduction of corticosteroid use is recommended. Other treatments may include:
Management of atrophoderma depends on the underlying cause. For steroid-induced atrophy, discontinuation or reduction of corticosteroid use is recommended. Other treatments may include:
* [[Topical retinoids]]
* [[Topical retinoids]]
* [[Laser therapy]]
* [[Laser therapy]]
* [[Phototherapy]]
* [[Phototherapy]]
== Prognosis ==
== Prognosis ==
The prognosis for atrophoderma varies. Some forms, such as steroid-induced atrophy, may improve with treatment, while others may persist or progress.
The prognosis for atrophoderma varies. Some forms, such as steroid-induced atrophy, may improve with treatment, while others may persist or progress.
 
== See Also ==
== Related pages ==
* [[Dermatology]]
* [[Dermatology]]
* [[Skin atrophy]]
* [[Skin atrophy]]
* [[Corticosteroids]]
* [[Corticosteroids]]
[[Category:Dermatology]]
[[Category:Dermatology]]
[[Category:Skin conditions]]
[[Category:Skin conditions]]

Latest revision as of 21:58, 5 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's medical weight loss NYC, sleep center NYC
Philadelphia medical weight loss and Philadelphia sleep clinics

Atrophoderma
Synonyms Atrophoderma of Pasini and Pierini
Pronounce N/A
Specialty Dermatology
Symptoms Thinning of the skin, loss of skin elasticity
Complications Scleroderma, Morphea
Onset Typically in adolescence or early adulthood
Duration Chronic
Types N/A
Causes Unknown, possibly autoimmune
Risks Family history, autoimmune disease
Diagnosis Clinical examination, skin biopsy
Differential diagnosis Morphea, Lichen sclerosus, Anetoderma
Prevention N/A
Treatment Topical corticosteroids, Phototherapy, Immunosuppressive drugs
Medication N/A
Prognosis Variable, may stabilize or progress
Frequency Rare
Deaths N/A


Atrophoderma is a term used to describe a group of skin conditions characterized by localized or diffuse thinning of the skin. This condition can result from a variety of causes, including genetic factors, inflammatory processes, or the use of certain medications such as corticosteroids.

Etiology[edit]

Atrophoderma can be classified based on its underlying cause:

  • Atrophoderma of Pasini and Pierini: A form of atrophoderma that presents as hyperpigmented, depressed patches on the skin, often on the trunk.
  • Steroid-induced atrophy: Prolonged use of topical or systemic corticosteroids can lead to thinning of the skin, known as steroid atrophy.
  • Anetoderma: Characterized by localized areas of slack skin due to loss of elastic tissue.

Clinical Presentation[edit]

The clinical features of atrophoderma vary depending on the specific type and cause. Common features include:

  • Thinning of the skin
  • Depressed or indented patches
  • Changes in skin pigmentation

Diagnosis[edit]

Diagnosis of atrophoderma is primarily clinical, based on the appearance of the skin. A skin biopsy may be performed to confirm the diagnosis and rule out other conditions.

Management[edit]

Management of atrophoderma depends on the underlying cause. For steroid-induced atrophy, discontinuation or reduction of corticosteroid use is recommended. Other treatments may include:

Prognosis[edit]

The prognosis for atrophoderma varies. Some forms, such as steroid-induced atrophy, may improve with treatment, while others may persist or progress.

See Also[edit]