Manganism: Difference between revisions
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{{Infobox medical condition | |||
[[File:Mn-TableImage.svg| | | name = Manganism | ||
| image = [[File:Mn-TableImage.svg|150px]] | |||
| caption = Manganese on the periodic table | |||
| synonyms = Manganese poisoning | |||
| specialty = [[Neurology]], [[Toxicology]] | |||
| symptoms = [[Tremor]], [[dystonia]], [[bradykinesia]], [[cognitive impairment]] | |||
| onset = Gradual | |||
| duration = Long-term | |||
| causes = [[Manganese]] exposure | |||
| risks = Occupational exposure (e.g., [[welding]], [[mining]]) | |||
| diagnosis = Clinical evaluation, [[MRI]] | |||
| differential = [[Parkinson's disease]], [[Wilson's disease]] | |||
| prevention = Reducing manganese exposure | |||
| treatment = [[Chelation therapy]], [[levodopa]] | |||
| prognosis = Variable, may be progressive | |||
| frequency = Rare | |||
}} | |||
'''Manganism''' is a neurological disorder caused by chronic exposure to [[manganese]] (Mn), a chemical element that is essential in small amounts but can be toxic in higher concentrations. This condition is characterized by symptoms similar to those of [[Parkinson's disease]], including tremors, difficulty walking, and facial muscle spasms. | '''Manganism''' is a neurological disorder caused by chronic exposure to [[manganese]] (Mn), a chemical element that is essential in small amounts but can be toxic in higher concentrations. This condition is characterized by symptoms similar to those of [[Parkinson's disease]], including tremors, difficulty walking, and facial muscle spasms. | ||
== Causes == | == Causes == | ||
Manganism is primarily caused by prolonged exposure to manganese dust or fumes. This exposure is common in certain occupational settings, such as [[welding]], [[mining]], and [[steel manufacturing]]. Manganese is used in the production of [[alloys]], [[batteries]], and [[fertilizers]], which can lead to increased risk of exposure for workers in these industries. | Manganism is primarily caused by prolonged exposure to manganese dust or fumes. This exposure is common in certain occupational settings, such as [[welding]], [[mining]], and [[steel manufacturing]]. Manganese is used in the production of [[alloys]], [[batteries]], and [[fertilizers]], which can lead to increased risk of exposure for workers in these industries. | ||
== Symptoms == | == Symptoms == | ||
The symptoms of manganism can be divided into early and late stages: | The symptoms of manganism can be divided into early and late stages: | ||
* '''Early symptoms''': | * '''Early symptoms''': | ||
* Fatigue | * Fatigue | ||
| Line 18: | Line 28: | ||
* Muscle cramps | * Muscle cramps | ||
* Emotional instability | * Emotional instability | ||
* '''Late symptoms''': | * '''Late symptoms''': | ||
* Tremors | * Tremors | ||
| Line 25: | Line 34: | ||
* Speech disturbances | * Speech disturbances | ||
* Facial muscle spasms | * Facial muscle spasms | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of manganism involves a combination of clinical evaluation and exposure history. Neurological examinations are conducted to assess motor function and cognitive abilities. Imaging techniques such as [[MRI]] may be used to detect changes in the brain associated with manganese exposure. | Diagnosis of manganism involves a combination of clinical evaluation and exposure history. Neurological examinations are conducted to assess motor function and cognitive abilities. Imaging techniques such as [[MRI]] may be used to detect changes in the brain associated with manganese exposure. | ||
== Treatment == | == Treatment == | ||
Treatment for manganism focuses on reducing manganese exposure and managing symptoms. Chelation therapy with agents such as [[EDTA]] may be used to remove excess manganese from the body. Supportive therapies, including physical therapy and medications to manage symptoms, are also important components of treatment. | Treatment for manganism focuses on reducing manganese exposure and managing symptoms. Chelation therapy with agents such as [[EDTA]] may be used to remove excess manganese from the body. Supportive therapies, including physical therapy and medications to manage symptoms, are also important components of treatment. | ||
== Prevention == | == Prevention == | ||
Preventing manganism involves minimizing exposure to manganese in occupational settings. This can be achieved through the use of protective equipment, proper ventilation, and adherence to safety regulations. Regular monitoring of manganese levels in the workplace and health surveillance of workers can also help prevent the onset of manganism. | Preventing manganism involves minimizing exposure to manganese in occupational settings. This can be achieved through the use of protective equipment, proper ventilation, and adherence to safety regulations. Regular monitoring of manganese levels in the workplace and health surveillance of workers can also help prevent the onset of manganism. | ||
== See also == | |||
== | |||
* [[Manganese]] | * [[Manganese]] | ||
* [[Parkinson's disease]] | * [[Parkinson's disease]] | ||
* [[Occupational safety and health]] | * [[Occupational safety and health]] | ||
[[Category:Neurological disorders]] | [[Category:Neurological disorders]] | ||
[[Category:Occupational diseases]] | [[Category:Occupational diseases]] | ||
Latest revision as of 03:44, 8 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Manganism | |
|---|---|
| |
| Synonyms | Manganese poisoning |
| Pronounce | N/A |
| Specialty | Neurology, Toxicology |
| Symptoms | Tremor, dystonia, bradykinesia, cognitive impairment |
| Complications | N/A |
| Onset | Gradual |
| Duration | Long-term |
| Types | N/A |
| Causes | Manganese exposure |
| Risks | Occupational exposure (e.g., welding, mining) |
| Diagnosis | Clinical evaluation, MRI |
| Differential diagnosis | Parkinson's disease, Wilson's disease |
| Prevention | Reducing manganese exposure |
| Treatment | Chelation therapy, levodopa |
| Medication | N/A |
| Prognosis | Variable, may be progressive |
| Frequency | Rare |
| Deaths | N/A |
Manganism is a neurological disorder caused by chronic exposure to manganese (Mn), a chemical element that is essential in small amounts but can be toxic in higher concentrations. This condition is characterized by symptoms similar to those of Parkinson's disease, including tremors, difficulty walking, and facial muscle spasms.
Causes[edit]
Manganism is primarily caused by prolonged exposure to manganese dust or fumes. This exposure is common in certain occupational settings, such as welding, mining, and steel manufacturing. Manganese is used in the production of alloys, batteries, and fertilizers, which can lead to increased risk of exposure for workers in these industries.
Symptoms[edit]
The symptoms of manganism can be divided into early and late stages:
- Early symptoms:
* Fatigue * Headache * Muscle cramps * Emotional instability
- Late symptoms:
* Tremors * Difficulty walking * Muscle rigidity * Speech disturbances * Facial muscle spasms
Diagnosis[edit]
Diagnosis of manganism involves a combination of clinical evaluation and exposure history. Neurological examinations are conducted to assess motor function and cognitive abilities. Imaging techniques such as MRI may be used to detect changes in the brain associated with manganese exposure.
Treatment[edit]
Treatment for manganism focuses on reducing manganese exposure and managing symptoms. Chelation therapy with agents such as EDTA may be used to remove excess manganese from the body. Supportive therapies, including physical therapy and medications to manage symptoms, are also important components of treatment.
Prevention[edit]
Preventing manganism involves minimizing exposure to manganese in occupational settings. This can be achieved through the use of protective equipment, proper ventilation, and adherence to safety regulations. Regular monitoring of manganese levels in the workplace and health surveillance of workers can also help prevent the onset of manganism.
