3F-PHP: Difference between revisions

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{{Short description|Synthetic stimulant drug}}
== 3F-PHP ==
{{Drugbox
| verifiedfields = changed
| verifiedrevid = 477002123
| image = 3F-PHP_structure.png
| image_size = 200px
| IUPAC_name = 1-(3-fluorophenyl)-2-(pyrrolidin-1-yl)hexan-1-one
}}


'''3F-PHP''' is a synthetic stimulant drug of the [[cathinone]] class. It is chemically related to [[3-FPM]] and other substituted cathinones. 3F-PHP is known for its stimulant effects and has been used recreationally.
[[File:3F-PHP_structure.png|thumb|right|Chemical structure of 3F-PHP]]


==Chemical structure==
'''3F-PHP''' is a synthetic stimulant of the [[cathinone]] class that has been used as a [[designer drug]]. It is chemically related to [[alpha-PHP]] and is known for its psychoactive effects. The compound is part of a broader category of substances known as [[substituted cathinones]], which are derivatives of the naturally occurring compound [[cathinone]] found in the [[khat]] plant.
3F-PHP is a fluorinated derivative of [[_-PHP]], with the chemical name 1-(3-fluorophenyl)-2-(pyrrolidin-1-yl)hexan-1-one. The presence of a fluorine atom on the phenyl ring distinguishes it from its non-fluorinated analogs.


==Pharmacology==
== Chemical Structure and Properties ==
3F-PHP acts as a [[central nervous system]] stimulant. It is believed to exert its effects by inhibiting the reuptake of [[dopamine]] and [[norepinephrine]], similar to other cathinones. This leads to increased concentrations of these neurotransmitters in the synaptic cleft, resulting in enhanced stimulation and euphoria.


==Effects==
3F-PHP, or 3-fluoro-alpha-pyrrolidinohexiophenone, is characterized by the presence of a fluorine atom at the third position of the phenyl ring. This modification is believed to influence the compound's pharmacological properties, including its potency and duration of action. The chemical structure of 3F-PHP is similar to other synthetic cathinones, featuring a pyrrolidine ring attached to the alpha carbon of the ketone moiety.
The effects of 3F-PHP are similar to those of other stimulant drugs. Users report increased energy, alertness, and euphoria. However, it can also cause adverse effects such as anxiety, paranoia, and increased heart rate.


==Legal status==
== Pharmacology ==
The legal status of 3F-PHP varies by country. In some jurisdictions, it is classified as a controlled substance, while in others it may be legal or unregulated. Users should be aware of the legal implications of possessing or using 3F-PHP in their region.


==Safety and risks==
As a stimulant, 3F-PHP is thought to act primarily as a [[dopamine]] and [[norepinephrine]] reuptake inhibitor, leading to increased concentrations of these neurotransmitters in the [[synaptic cleft]]. This action is responsible for the stimulating and euphoric effects reported by users. The compound's effects are similar to those of other synthetic cathinones, which are often compared to [[amphetamine]]s in terms of their stimulant properties.
As with other synthetic stimulants, the use of 3F-PHP carries potential risks. These include the possibility of addiction, cardiovascular issues, and neurotoxicity. The lack of research on its long-term effects further complicates the assessment of its safety profile.
 
== Usage and Effects ==
 
3F-PHP is typically encountered in the form of a white crystalline powder and is often consumed orally, nasally, or via vaporization. Users report effects such as increased energy, alertness, and euphoria, as well as potential adverse effects like anxiety, paranoia, and cardiovascular issues. The onset of effects is rapid, and the duration can vary depending on the route of administration and individual metabolism.
 
== Legal Status ==
 
The legal status of 3F-PHP varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. The compound is often included in legislation targeting [[new psychoactive substances]] (NPS), which are designed to circumvent existing drug laws.
 
== Health Risks and Concerns ==
 
The use of 3F-PHP, like other synthetic cathinones, is associated with a range of health risks. Acute effects can include [[tachycardia]], [[hypertension]], and [[hyperthermia]], while chronic use may lead to psychological dependence and cognitive impairments. The lack of clinical research on 3F-PHP means that its long-term effects are not well understood, posing additional risks to users.
 
== Related Pages ==


==Related pages==
* [[Cathinone]]
* [[Cathinone]]
* [[3-FPM]]
* [[Synthetic cathinones]]
* [[_-PHP]]
* [[Designer drugs]]
* [[Stimulant]]
* [[Dopamine reuptake inhibitor]]
 
* [[Norepinephrine reuptake inhibitor]]
==Gallery==
<gallery>
3F-PHP_structure.png|Chemical structure of 3F-PHP
</gallery>


[[Category:Cathinones]]
[[Category:Synthetic cathinones]]
[[Category:Stimulants]]
[[Category:Designer drugs]]
[[Category:Designer drugs]]

Latest revision as of 03:49, 13 February 2025

3F-PHP[edit]

Chemical structure of 3F-PHP

3F-PHP is a synthetic stimulant of the cathinone class that has been used as a designer drug. It is chemically related to alpha-PHP and is known for its psychoactive effects. The compound is part of a broader category of substances known as substituted cathinones, which are derivatives of the naturally occurring compound cathinone found in the khat plant.

Chemical Structure and Properties[edit]

3F-PHP, or 3-fluoro-alpha-pyrrolidinohexiophenone, is characterized by the presence of a fluorine atom at the third position of the phenyl ring. This modification is believed to influence the compound's pharmacological properties, including its potency and duration of action. The chemical structure of 3F-PHP is similar to other synthetic cathinones, featuring a pyrrolidine ring attached to the alpha carbon of the ketone moiety.

Pharmacology[edit]

As a stimulant, 3F-PHP is thought to act primarily as a dopamine and norepinephrine reuptake inhibitor, leading to increased concentrations of these neurotransmitters in the synaptic cleft. This action is responsible for the stimulating and euphoric effects reported by users. The compound's effects are similar to those of other synthetic cathinones, which are often compared to amphetamines in terms of their stimulant properties.

Usage and Effects[edit]

3F-PHP is typically encountered in the form of a white crystalline powder and is often consumed orally, nasally, or via vaporization. Users report effects such as increased energy, alertness, and euphoria, as well as potential adverse effects like anxiety, paranoia, and cardiovascular issues. The onset of effects is rapid, and the duration can vary depending on the route of administration and individual metabolism.

Legal Status[edit]

The legal status of 3F-PHP varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. The compound is often included in legislation targeting new psychoactive substances (NPS), which are designed to circumvent existing drug laws.

Health Risks and Concerns[edit]

The use of 3F-PHP, like other synthetic cathinones, is associated with a range of health risks. Acute effects can include tachycardia, hypertension, and hyperthermia, while chronic use may lead to psychological dependence and cognitive impairments. The lack of clinical research on 3F-PHP means that its long-term effects are not well understood, posing additional risks to users.

Related Pages[edit]