System: Difference between revisions
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A '''systemic disease''' is a condition that affects multiple organs and tissues, or the body as a whole. Unlike localized diseases, which affect a specific part of the body, systemic diseases can have widespread effects and often involve complex interactions between different bodily systems. | A '''systemic disease''' is a condition that affects multiple organs and tissues, or the body as a whole. Unlike localized diseases, which affect a specific part of the body, systemic diseases can have widespread effects and often involve complex interactions between different bodily systems. | ||
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* [[Multisystem disorder]] | * [[Multisystem disorder]] | ||
* [[Systemic inflammatory response syndrome]] | * [[Systemic inflammatory response syndrome]] | ||
==External Links== | ==External Links== | ||
* [https://www.who.int/health-topics/systemic-diseases World Health Organization - Systemic Diseases] | * [https://www.who.int/health-topics/systemic-diseases World Health Organization - Systemic Diseases] | ||
* [https://www.cdc.gov/diseasesconditions/systemic-diseases.html CDC - Systemic Diseases] | * [https://www.cdc.gov/diseasesconditions/systemic-diseases.html CDC - Systemic Diseases] | ||
{{nt}} | |||
{{Medical conditions}} | {{Medical conditions}} | ||
[[Category:Systemic diseases]] | [[Category:Systemic diseases]] | ||
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[[Category:Autoimmune diseases]] | [[Category:Autoimmune diseases]] | ||
[[Category:Infectious diseases]] | [[Category:Infectious diseases]] | ||
<gallery> | |||
File:Diagram_Systems.svg|Diagram Systems | |||
File:OpenSystemRepresentation.svg|Open System Representation | |||
</gallery> | |||
Latest revision as of 21:41, 23 February 2025
A systemic disease is a condition that affects multiple organs and tissues, or the body as a whole. Unlike localized diseases, which affect a specific part of the body, systemic diseases can have widespread effects and often involve complex interactions between different bodily systems.
Classification[edit]
Systemic diseases can be classified based on their etiology, including:
- Autoimmune diseases: Conditions where the immune system attacks the body's own tissues, such as systemic lupus erythematosus and rheumatoid arthritis.
- Infectious diseases: Diseases caused by pathogens that spread throughout the body, such as HIV/AIDS and tuberculosis.
- Metabolic disorders: Conditions that affect the body's metabolism, such as diabetes mellitus and hyperthyroidism.
- Genetic disorders: Diseases caused by genetic mutations, such as cystic fibrosis and Marfan syndrome.
Pathophysiology[edit]
The pathophysiology of systemic diseases varies widely depending on the specific condition. However, common mechanisms include:
- Inflammation: A key feature in many systemic diseases, where the body's immune response leads to tissue damage.
- Autoimmunity: The immune system mistakenly targets the body's own cells.
- Infection: Pathogens spread through the bloodstream or lymphatic system, affecting multiple organs.
- Metabolic imbalance: Disruptions in normal metabolic processes can lead to systemic effects.
Symptoms[edit]
Symptoms of systemic diseases can be diverse and may include:
Diagnosis[edit]
Diagnosing systemic diseases often requires a combination of:
- Medical history and physical examination
- Laboratory tests: Including blood tests to check for markers of inflammation or infection.
- Imaging studies: Such as X-rays, CT scans, or MRI to assess organ involvement.
- Biopsy: Taking a tissue sample for analysis.
Treatment[edit]
Treatment strategies for systemic diseases depend on the underlying cause and may include:
- Pharmacotherapy: Medications such as immunosuppressants, antibiotics, or hormone replacement therapy.
- Surgery: To remove or repair affected tissues or organs.
- Lifestyle modifications: Including diet, exercise, and stress management.
- Supportive care: To manage symptoms and improve quality of life.
Prognosis[edit]
The prognosis for systemic diseases varies widely. Some conditions can be managed effectively with treatment, while others may lead to chronic disability or be life-threatening.
Research and Future Directions[edit]
Ongoing research into systemic diseases focuses on:
- Understanding the genetic and environmental factors that contribute to these conditions.
- Developing targeted therapies that address the underlying mechanisms of disease.
- Improving diagnostic techniques for earlier and more accurate detection.
See Also[edit]
External Links[edit]
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Diagram Systems
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Open System Representation
