Tibrovirus: Difference between revisions

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{{Infobox virus
{{DISPLAYTITLE:Tibrovirus}}
| name = Tibrovirus
| virus_group = v
| ordo = [[Mononegavirales]]
| familia = [[Rhabdoviridae]]
| genus = Tibrovirus
}}


'''Tibrovirus''' is a genus of viruses in the family [[Rhabdoviridae]], order [[Mononegavirales]]. Members of this genus are known to infect vertebrates, including humans and animals. The genus is named after the town of [[Tibooburra]] in Australia, where the first virus of this genus was isolated.
== Overview ==
[[File:Sweetwater_branch_virus.jpg|thumb|right|Electron micrograph of a Tibrovirus particle]]
'''Tibrovirus''' is a genus of viruses in the family [[Rhabdoviridae]]. These viruses are known to infect mammals and are primarily transmitted through [[arthropod]] vectors. The genus is named after the town of Tibro in Sweden, where the first virus of this genus was isolated.


==Virology==
== Structure ==
Tibroviruses are enveloped viruses with a single-stranded, negative-sense RNA genome. The genome is approximately 11-12 kilobases in length and encodes five proteins: the nucleoprotein (N), phosphoprotein (P), matrix protein (M), glycoprotein (G), and the large polymerase protein (L). These proteins are typical of the [[Rhabdoviridae]] family.
Tibroviruses are characterized by their [[enveloped virus|enveloped]] structure and a [[helical symmetry|helical]] [[nucleocapsid]]. The virions are typically bullet-shaped, a common feature among members of the Rhabdoviridae family. The genome is composed of a single-stranded, negative-sense [[RNA]] molecule.


===Structure===
== Genome ==
The virions are bullet-shaped, a characteristic feature of rhabdoviruses. The envelope is derived from the host cell membrane and contains the viral glycoprotein spikes, which are responsible for attachment to host cells.
The genome of Tibroviruses is approximately 11-12 kilobases in length and encodes five proteins. These include the [[nucleoprotein]] (N), the [[phosphoprotein]] (P), the [[matrix protein]] (M), the [[glycoprotein]] (G), and the [[RNA-dependent RNA polymerase]] (L). The organization of these genes is similar to other rhabdoviruses.


===Genome===
== Transmission ==
The genome organization of tibroviruses follows the typical rhabdovirus pattern: 3'-N-P-M-G-L-5'. The negative-sense RNA genome is encapsidated by the nucleoprotein, forming a ribonucleoprotein complex that is essential for replication and transcription.
Tibroviruses are primarily transmitted through the bites of infected arthropods, such as [[mosquitoes]] and [[ticks]]. The specific vectors and hosts can vary depending on the virus species within the genus.


==Pathogenesis==
== Pathogenesis ==
Tibroviruses are primarily transmitted through arthropod vectors, such as mosquitoes and ticks. They can cause febrile illnesses in humans and animals, although the full spectrum of diseases associated with tibrovirus infections is not completely understood.
The pathogenesis of Tibrovirus infections in humans and animals is not well understood. Some Tibroviruses have been associated with mild febrile illnesses in humans, but more research is needed to fully elucidate their clinical significance.


==Epidemiology==
== Species ==
Tibroviruses have been isolated in various regions, including Australia and Africa. The distribution of these viruses is closely linked to the presence of their arthropod vectors.
The genus Tibrovirus includes several species, with the most well-known being the [[Sweetwater branch virus]]. Other species have been identified, but their roles in disease and ecology are still under investigation.


==Species==
== Research ==
The genus Tibrovirus includes several species, such as:
Research on Tibroviruses is ongoing, with studies focusing on their molecular biology, ecology, and potential impact on human and animal health. Understanding the transmission dynamics and host interactions is crucial for developing strategies to prevent and control infections.
* '''Tibrogargan virus'''
* '''Coastal Plains virus'''


==Research and Public Health==
== Related pages ==
Research on tibroviruses is ongoing to better understand their biology, transmission, and potential impact on public health. Surveillance and vector control are important measures to prevent outbreaks of tibrovirus-associated diseases.
 
==Also see==
* [[Rhabdoviridae]]
* [[Rhabdoviridae]]
* [[Mononegavirales]]
* [[Arthropod-borne virus]]
* [[Arthropod-borne virus]]
* [[Viral pathogenesis]]
* [[Viral pathogenesis]]


{{Virus-stub}}
[[Category:Viruses]]
 
[[Category:Rhabdoviridae]]
[[Category:Rhabdoviridae]]
[[Category:Mononegavirales]]
[[Category:Arthropod-borne viruses]]

Latest revision as of 11:39, 15 February 2025


Overview[edit]

Electron micrograph of a Tibrovirus particle

Tibrovirus is a genus of viruses in the family Rhabdoviridae. These viruses are known to infect mammals and are primarily transmitted through arthropod vectors. The genus is named after the town of Tibro in Sweden, where the first virus of this genus was isolated.

Structure[edit]

Tibroviruses are characterized by their enveloped structure and a helical nucleocapsid. The virions are typically bullet-shaped, a common feature among members of the Rhabdoviridae family. The genome is composed of a single-stranded, negative-sense RNA molecule.

Genome[edit]

The genome of Tibroviruses is approximately 11-12 kilobases in length and encodes five proteins. These include the nucleoprotein (N), the phosphoprotein (P), the matrix protein (M), the glycoprotein (G), and the RNA-dependent RNA polymerase (L). The organization of these genes is similar to other rhabdoviruses.

Transmission[edit]

Tibroviruses are primarily transmitted through the bites of infected arthropods, such as mosquitoes and ticks. The specific vectors and hosts can vary depending on the virus species within the genus.

Pathogenesis[edit]

The pathogenesis of Tibrovirus infections in humans and animals is not well understood. Some Tibroviruses have been associated with mild febrile illnesses in humans, but more research is needed to fully elucidate their clinical significance.

Species[edit]

The genus Tibrovirus includes several species, with the most well-known being the Sweetwater branch virus. Other species have been identified, but their roles in disease and ecology are still under investigation.

Research[edit]

Research on Tibroviruses is ongoing, with studies focusing on their molecular biology, ecology, and potential impact on human and animal health. Understanding the transmission dynamics and host interactions is crucial for developing strategies to prevent and control infections.

Related pages[edit]