ATP: Difference between revisions

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'''Adenosine triphosphate''' ('''ATP''') is a [[nucleotide]] that serves as the primary energy carrier in all living organisms. It is often referred to as the "molecular unit of currency" of intracellular energy transfer. ATP transports chemical energy within cells for [[metabolism]].
{{Infobox biochemical compound
| Name = Adenosine Triphosphate (ATP)
| Image =
| Caption =
| Abbreviations = ATP
| Chemical_formula = C10H16N5O13P3
}}
 
'''Adenosine Triphosphate''' ('''ATP''') is a complex organic [[chemical]] that participates in many processes within [[cell]]ular organisms. ATP is often referred to as the "molecular unit of currency" of intracellular energy transfer. ATP transports chemical energy within [[cells]] for [[metabolism]]. It is one of the end products of [[photosynthesis]] and [[cellular respiration]] and is used by enzymes and structural proteins in many cellular processes, including [[biosynthetic reactions]], [[muscle contraction]], and [[active transport]] across [[cell membrane]]s.


== Structure ==
== Structure ==
ATP consists of three main components:
ATP consists of [[adenine]], [[ribose]] (a [[sugar]]), and three [[phosphate]] groups. The bond between the second and third phosphate groups, known as the "high-energy" bond, is the source of energy released during hydrolysis.
* A [[adenine]] base
* A [[ribose]] sugar
* Three [[phosphate]] groups
 
The bonds between the phosphate groups are high-energy bonds, and their hydrolysis releases energy that can be used for various cellular processes.


== Function ==
== Function ==
ATP is used in various cellular processes, including:
ATP performs multiple functions in the cell, but its primary role is to drive energy-consuming processes. Energy is released by hydrolyzing ATP into [[adenosine diphosphate]] (ADP) and a free phosphate group. This energy is then used to perform work within the cell, such as [[muscular contraction]], [[protein synthesis]], and [[nerve impulse]] propagation.
* [[Muscle contraction]]
* [[Protein synthesis]]
* [[Cell division]]
* [[Active transport]] across cell membranes


== Synthesis ==
== Synthesis ==
ATP is synthesized through several pathways:
ATP is synthesized from ADP and inorganic phosphate via two principal pathways:
* [[Cellular respiration]] in the [[mitochondria]]
* [[Oxidative phosphorylation]] in the [[mitochondria]], part of cellular respiration, which is the primary method used by eukaryotic cells.
* [[Photosynthesis]] in [[chloroplasts]]
* [[Photophosphorylation]] in the [[chloroplasts]] of plant cells, occurring during photosynthesis.
* [[Fermentation]] in the absence of oxygen


== Hydrolysis ==
== Role in the Cell ==
The hydrolysis of ATP to [[adenosine diphosphate]] (ADP) and an inorganic phosphate (Pi) releases energy. This reaction is catalyzed by enzymes known as [[ATPases]].
ATP is crucial in the transport of [[macromolecules]] across cell membranes, e.g., exocytosis and endocytosis. It also plays a critical role in the synthesis of [[nucleic acids]].
 
== Role in Metabolism ==
ATP plays a crucial role in [[metabolism]], acting as a coenzyme in many enzymatic reactions. It is involved in:
* [[Glycolysis]]
* [[Krebs cycle]]
* [[Electron transport chain]]


== ATP Cycle ==
== ATP Cycle ==
The ATP cycle is a continuous process of ATP synthesis and hydrolysis. Cells constantly regenerate ATP from ADP and Pi through cellular respiration and other metabolic pathways.
The ATP cycle is the process by which ATP is broken down into ADP and phosphate to release energy, and then re-synthesized using the energy derived from food or sunlight. This cycle is a critical component of the [[cell's metabolism]].


== Importance in Medicine ==
== Health Implications ==
ATP is essential for the proper functioning of cells and is a focus of research in various medical fields, including [[cardiology]], [[neurology]], and [[oncology]].
Abnormalities in ATP synthesis are linked to various diseases, including [[mitochondrial diseases]], [[cardiomyopathies]], and certain types of [[muscular dystrophies]].


== See Also ==
== See Also ==
* [[ADP]]
* [[Adenosine diphosphate]] (ADP)
* [[AMP]]
* [[Energy]]
* [[NADH]]
* [[Metabolism]]
* [[FADH2]]
* [[Cell biology]]
* [[Energy metabolism]]
 
== References ==
{{Reflist}}
 
== External Links ==
{{Commons category|Adenosine triphosphate}}


[[Category:Biochemistry]]
[[Category:Biochemistry]]
[[Category:Cell biology]]
[[Category:Cell biology]]
[[Category:Metabolism]]
[[Category:Metabolism]]
[[Category:Nucleotides]]
[[Category:Energy]]


{{medicine-stub}}
{{Biochemistry-stub}}

Latest revision as of 16:22, 13 August 2024

Template:Infobox biochemical compound

Adenosine Triphosphate (ATP) is a complex organic chemical that participates in many processes within cellular organisms. ATP is often referred to as the "molecular unit of currency" of intracellular energy transfer. ATP transports chemical energy within cells for metabolism. It is one of the end products of photosynthesis and cellular respiration and is used by enzymes and structural proteins in many cellular processes, including biosynthetic reactions, muscle contraction, and active transport across cell membranes.

Structure[edit]

ATP consists of adenine, ribose (a sugar), and three phosphate groups. The bond between the second and third phosphate groups, known as the "high-energy" bond, is the source of energy released during hydrolysis.

Function[edit]

ATP performs multiple functions in the cell, but its primary role is to drive energy-consuming processes. Energy is released by hydrolyzing ATP into adenosine diphosphate (ADP) and a free phosphate group. This energy is then used to perform work within the cell, such as muscular contraction, protein synthesis, and nerve impulse propagation.

Synthesis[edit]

ATP is synthesized from ADP and inorganic phosphate via two principal pathways:

Role in the Cell[edit]

ATP is crucial in the transport of macromolecules across cell membranes, e.g., exocytosis and endocytosis. It also plays a critical role in the synthesis of nucleic acids.

ATP Cycle[edit]

The ATP cycle is the process by which ATP is broken down into ADP and phosphate to release energy, and then re-synthesized using the energy derived from food or sunlight. This cycle is a critical component of the cell's metabolism.

Health Implications[edit]

Abnormalities in ATP synthesis are linked to various diseases, including mitochondrial diseases, cardiomyopathies, and certain types of muscular dystrophies.

See Also[edit]


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